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    Jackowski: News Releases & Feature Stories

    Study shows metabolic strategy of stressed cell

    St. Jude investigators have mapped out many of the dynamic genetic and biochemical changes that make up a cell's response to a shortage of a molecule called Coenzyme A (CoA), a key player in metabolism.

    3-D forms link antibiotic resistance and brain disease

    St. Jude uses computer-generated images of different types of same enzyme to unlock mysteries of antibiotic resistance and a rare form of brain degeneration.

    Gene regulated by need to process proteins linked to enlargement of protein processing factory

    The mechanism that folds proteins into their proper shapes also increases the cell's capacity for folding and shipping proteins. This allows efficient protein folding and packaging, which must occur thousands of times a minute in response to infections.