Medicine and Science News Releases

View recent medicine and science-related news releases.

 
12/17/2014
Cells identified that enhance tumor growth and suppress anti-cancer immune attack

St. Jude Children’s Research Hospital scientists used a novel strategy to find the white blood cells that tumors rely on to suppress the immune response; results provide foundation for efforts to improve immunotherapy. (Peter Murray, PhD)

 
 
12/11/2014
Youngest bone marrow transplant patients at higher risk of cognitive decline

St. Jude Children’s Research Hospital study identifies small group of patients at risk for intellectual decline after bone marrow transplantation; results set stage for new strategies to preserve IQ and fight cancer. (Sean Phipps, PhD)

 
 
12/05/2014
Promising compound rapidly eliminates malaria parasite

An international research collaborative led by St. Jude Children’s Research Hospital reports that the rapid action of (+)-SJ733 will likely slow malaria drug resistance; human safety trials of the compound are planned. (R. Kiplin Guy, PhD)

 
 
11/24/2014
Survivors of childhood eye cancer experience normal cognitive functioning as adults

St. Jude Children’s Research Hospital study found adults diagnosed with retinoblastoma as infants often performed better on tasks than survivors diagnosed at an older age; suggests brain may compensate for early insult. (Tara Brinkman, PhD)

 
 
11/19/2014
Gene therapy provides safe, long-term relief for patients with severe hemophilia B

Gene therapy pioneered by St. Jude Children’s Research Hospital, University College London and the Royal Free Hospital provides provided men with hemophilia B reliable relief from the bleeding disorder, paving the way for more active lifestyles

 
 
11/12/2014
Gene sequencing projects link two mutations to Ewing sarcoma subtype with poor prognosis

St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project and Institut Curie-Inserm lead collaboration that lays the foundation for precision medicine against bone and soft tissue tumor

 
 
11/03/2014
Telephone counseling leads more adult childhood cancer survivors to get heart screenings

St. Jude Children’s Research Hospital-led national study finds that brief telephone counseling by advanced-practice nurses prompts more childhood cancer survivors to get recommended heart screenings. (Melissa Hudson, MD)

 
 
11/03/2014
St. Jude Children’s Research Hospital appoints scientific director

Richard Gilbertson, M.D., Ph.D., to direct scientific enterprise for the institution

 
 
10/23/2014
Experimental breast cancer drug holds promise in combination therapy for Ewing sarcoma

St. Jude Children’s Research Hospital researchers have identified a promising new triple-drug combination therapy that exploits DNA repair problem in Ewing sarcoma tumors; clinical trials expected to open soon. (Michael Dyer, PhD, Anang Shelat, PhD, Elizabeth Stewart, MD)

 
 
10/02/2014
Diet affects mix of intestinal bacteria and the risk of inflammatory bone disease

St. Jude Children’s Research Hospital study finds diet may influence susceptibility to autoinflammatory disease in at-risk individuals by favoring intestinal bacteria that fuel or dampen inflammation. (Thirumala-Devi Kanneganti, PhD)

 
 
09/24/2014
Good news for young patients with a leukemia subtype associated with a poor prognosis

St. Jude Children’s Research Hospital study shows that adjusting treatment based on early response to chemotherapy boosts survival of young patients with Philadelphia chromosome-like acute lymphoblastic leukemia. (Ching-Hon Pui, MD)

 
 
09/16/2014
Improved risk identification will aid fertility preservation in young male cancer patients

St. Jude Children’s Research Hospital study has identified the cumulative dose of a widely used class of chemotherapy drugs that leaves young male cancer patients at risk for impaired sperm production as adults. (Daniel Green, MD)

 
 
09/10/2014
Genomic analysis reveals that a high-risk leukemia subtype becomes more common with age

Stage set to determine if drugs called tyrosine kinase inhibitors will extend the lives of patients with the high-risk acute lymphoblastic leukemia subtype; pediatric clinical trial scheduled to open by early 2015. (Charles Mullighan, MBBS(Hons), MSc, MD)

 
 
09/04/2014
Avian influenza virus isolated in harbor seals poses a threat to humans

St. Jude Children’s Research Hospital-led study found naturally acquired mutations in the avian H3N8 flu virus allow the infection to spread in mammals via respiratory droplets; human immunity to the virus is lacking. (Stacey Schultz-Cherry, PhD)

 
 
08/11/2014
St. Jude Children’s Research Hospital oncologist elected to Academia Sinica, the highest academic institution in Taiwan

Ching-Hon Pui, M.D., recognized for pioneering research and treatment of childhood leukemia, increasing childhood cancer survival rates around the globe. (Dr. Ching-Hon Pui)

 
 
08/06/2014
Discovery yields master regulator of toxin production in staph infections

St. Jude Children’s Research Hospital discovery lays the groundwork for a new class of antibiotics to fight multi-drug resistant Staphylococcus aureus and related bacteria that cause serious infections. (Charles Rock, PhD)

 
 
07/28/2014
Unhealthy habits more than double risk of metabolic syndrome in childhood cancer survivors

St. Jude Children’s Research Hospital study finds that few adult survivors of childhood cancer follow a heart-healthy lifestyle that protects against heart disease, diabetes and other health problems. (Kirsten Ness, PhD)

 
 
07/28/2014
St. Jude Children’s Research Hospital receives Secretary of Defense Employer Support Freedom Award

St. Jude is one of 15 recipients honored for supporting military personnel.

 
 
07/22/2014
HIV clinic-based audio project emphasizes the power of patient voices

Patients become teachers through an innovative, clinic-based audio project of St. Jude Children’s Research Hospital that gives youth infected with HIV a chance to share their experiences with the diagnosis. (Aditya Gaur, MD)

 
 
07/02/2014
Protein’s structural shift offers clues to tumor suppression and other key cell functions

A St. Jude Children’s Research Hospital study identifies the mechanism underlying a shape-shifting protein that assists in tumor suppression; results could aid cancer drug development. (Dr. Richard Kriwacki, PhD)

 
 
06/25/2014
St. Jude Children's Research Hospital names James R. Downing, MD, CEO to oversee a new era of expansion, growth

Downing, internationally recognized as a genome sequencing pioneer and member of the National Academy of Sciences’ Institute of Medicine, becomes sixth leader to serve at hospital’s helm. (James Downing, MD)

 
 
06/19/2014
Mechanism discovered for attaching an “on” switch that helps cells accessorize proteins

St. Jude Children’s Research Hospital scientists advance understanding of how cells manage their vast array of proteins and how system failures can lead to cancer and other diseases. (Brenda Schulman, PhD)

 
 
06/11/2014
St. Jude Children’s Research Hospital renewed as NCI-designated Comprehensive Cancer Center

St. Jude Comprehensive Cancer Center receives “exceptional” score from National Cancer Institute—highest rating awarded to cancer centers.

 
 
06/10/2014
St. Jude Children’s Research Hospital adding department and faculty to aid mission

Internationally recognized physician-scientists joining fight against devastating childhood diseases as hospital expands clinical and basic science research .

 
 
06/05/2014
Brain circuit problem likely sets stage for the “voices” that are symptom of schizophrenia

St. Jude Children’s Research Hospital scientists report that a disruption in a brain circuit may contribute to the auditory hallucinations of schizophrenia. (Stanislav Zakharenko, MD, PhD)

 
 
05/30/2014
St. Jude researcher honored by the American Society of Clinical Oncology for work in childhood cancer survivorship

Leslie Robison, Ph.D., becomes the fifth researcher from St. Jude Children’s Research Hospital to receive the Pediatric Oncology Award.

 
 
05/22/2014
Bacterial adaptation contributes to pneumococcal threat in sickle cell disease patients

St. Jude Children’s Research Hospital-led study reveals differences in the pneumococcal genome that explain why current vaccines aren’t better at protecting children with sickle cell disease from the bacterial infection. (Jason Rosch, PhD)

 
 
05/20/2014
Molecule acts as umpire to make tough life-or-death calls

St. Jude Children’s Research Hospital solves mystery of enzyme’s role in cell survival, offering clues of how immune system fights infection and possible strategies to treat problems ranging from heart attack to cancer. (Douglas Green, PhD)

 
 
05/15/2014
Detailed studies reveal how key cancer-fighting protein is held in check

St. Jude Children’s Research Hospital analysis reveals how the protein p53, which triggers cancer cells to commit suicide, attaches to its regulatory molecule; findings could lead to drugs to unleash p53 to battle a range of cancers. (Richard Kriwacki, PhD, and Douglas Green, PhD)

 
 
05/09/2014
Discovery links rare, childhood neurodegenerative diseases to common problem in DNA repair

The study of two rare childhood neurodegenerative diseases leads St. Jude Children’s Research Hospital scientists to a new source of DNA damage that may play a role in a wide range of health problems, including cancer. (Peter McKinnon, PhD)

 
 
05/08/2014
Experimental antibody shows early promise for treatment of childhood tumor

Tumors shrank or disappeared in some patients with advanced neuroblastoma in a Phase I study of an immune therapy manufactured at St. Jude Children’s Research Hospital. (Fariba Navid, MD)

 
 
05/07/2014
St. Jude Children’s Research Hospital ranked as the No. 1 preferred company to work for by millennials

For the second consecutive year, St. Jude leads the list of places students and young professionals want to work

 
 
05/01/2014
St. Jude Children’s Research Hospital scientist elected to National Academy of Sciences

Brenda Schulman, Ph.D., of St. Jude Children’s Research Hospital, has been elected to the National Academy of Sciences (NAS). Membership in the academy is a widely accepted mark of excellence in science and is considered one of the highest honors a scientist can receive.

 
 
04/30/2014
St. Jude Children’s Research Hospital named finalist for Secretary of Defense Employer Support Freedom Award

St. Jude is one of 30 finalists honored for supporting military personnel.

 
 
04/11/2014
St. Jude Children’s Research Hospital named national center of excellence for flu research

St. Jude again designated Center of Excellence for Influenza Research and Surveillance by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

 
 
04/06/2014
Gene sequencing project discovers mutations tied to deadly brain tumors in young children

St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project offers new leads to improved outcomes for children with high-grade glioma brain tumors; particularly youngest patients. (Suzanne Baker, PhD, and Jinghui Zhang, PhD)

 
 
04/03/2014
Tumor suppressor gene TP53 mutated in 90 percent of most common childhood bone tumor

St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project finds TP53 gene is altered in nearly all osteosarcomas; results help explain how tumors withstand radiation therapy. (Michael Dyer, PhD, and Jinghui Zhang, PhD)

 
 
03/27/2014
Adult cancer drugs show promise against an aggressive childhood brain tumor

A St. Jude Children’s Research Hospital-led study identified two adult cancer drugs with potential to improve treatment of a high-risk childhood brain tumor; the drugs are now part of a pediatric clinical trial. (Martine Roussel, PhD)

 
 
03/17/2014
Health gap between adult survivors of childhood cancer and siblings widens with age

St. Jude Children’s Research Hospital and the Childhood Cancer Survivor Study: Long-term follow-up of adult survivors of childhood cancer reinforces need for lifelong health surveillance for childhood cancer survivors. (Gregory Armstrong, MD)

 
 
02/19/2014
Gene sequencing project discovers common driver of a childhood brain tumor

St. Jude Children’s Research Hospital -Washington University Pediatric Cancer Genome Project identifies the most common genetic alteration yet in the brain tumor ependymoma; results offer clues for fighting other cancers. (Richard Gilbertson, MD, PhD, David Ellison, MD, PhD, Jinghui Zhang, PhD)

 
 
02/10/2014
Researchers discover immune signature that predicts poor outcome in influenza patients

A study led by St. Jude Children’s Research Hospital identifies factors that predict flu severity in patients and sets the stage for more effective therapies to prevent flu complications and deaths (Paul Thomas, PhD)

 
 
02/05/2014
Mechanism discovered for how amyotrophic lateral sclerosis mutations damage nerve function

A study led by St. Jude Children’s Research Hospital offers a new avenue for scientists to pursue in the quest for desperately needed treatments for ALS. (J. Paul Taylor, MD, PhD)

 
 
01/27/2014
Promising class of antibiotics discovered for treatment of drug-resistant tuberculosis

Research led by St. Jude Children’s Research Hospital scientists has produced new versions of an old antibiotic that are active against difficult-to-treat tuberculosis; offers new strategy for overcoming drug resistance. (Richard Lee, PhD)

 
 
01/21/2014
Cancer diagnosis doesn’t increase a child’s risk of post-traumatic stress disorder

St. Jude Children’s Research Hospital study suggests previous research overestimated PTSD in young cancer patients; new findings highlight the ability of children to adjust and even thrive in response to challenges. (Sean Phipps, PhD)

 
 
01/16/2014
St. Jude Children’s Research Hospital makes FORTUNE magazine “100 Best Companies to Work For” list for fourth year

St. Jude Children’s Research Hospital has been recognized for the fourth consecutive year as one of FORTUNE magazine’s “100 Best Companies to Work For.”