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Alternate Names: AML, non-lymphoid, myeloblastic, granulocytic, myelocytic leukemia
Acute myeloid leukemia (AML ) affects various white blood cells including granulocytes, monocytes and platelets. Leukemic cells accumulate in the bone marrow, replace normal blood cells and can spread to the liver, spleen, skin, or central nervous system.
There is a greater incidence of leukemia among people exposed to large amounts of radiation and certain chemicals (e.g. benzene).
Although approximately 80 to 90 percent of children with acute myeloid leukemia attain remissions (absence of leukemic cells), some of those patients have later recurrences. About 70 percent of children with AML achieve long-term remissions with chemotherapy or stem cell transplantation.
St. Jude Children's Research Hospital has committed substantial resources to study the fundamental mechanisms of acute myeloid leukemia. In addition, St. Jude investigators are trying innovative forms of treatment to improve the outcome of this deadly disease. Current clinical trials include:
The St. Jude Web site is designed for educational purposes only and is not engaged in rendering medical advice or professional services. The information provided through this site should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. If you have or suspect you may have a health problem, you should consult your health care provider.