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St. Jude Children’s Research Hospital scientists have made a surprising connection between a rare disorder that strikes young people and Alzheimer’s disease, a disease that usually affects older people.
St. Jude Children’s Research Hospital scientists identify enzyme that could lead to better diagnosis and treatment of Alzheimer’s disease and related disorders. (Dr. Alessandra d'Azzo)
St. Jude Children’s Research Hospital scientists lead effort that reveals new details linking lipid build-up with catastrophic calcium imbalance in brain cells of patients with rare, inherited disorder.
To find answers for children with "orphan diseases," one St. Jude researcher digs into the mysteries of the human cell.
Physicians might one day be able to treat a disease that destroys brain cells in children using genetically modified cells to transport a "drug" to the site of the dying neural cells (cells that transmit impulses).
Disruption of protein-folding in neuronal cells causes neurodegeneration and mental retardation.
Research conducted by St. Jude investigators led by Alessandra d'Azzo, PhD, may help uncover the genetic cause of certain muscle diseases that occur for unknown reasons in children.