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    Zhang: News Releases & Feature Stories

     
    05/04/2015
    Scientists dramatically improve method for finding common genetic alterations in tumors

    St. Jude Children’s Research Hospital scientists developed a new computer tool to find DNA duplications and deletions that play pivotal roles in adult and childhood cancers; the tool is free to researchers worldwide. (Jinghui Zhang, PhD)

     
     
    03/19/2015
    Scientists trace genomic evolution of high-risk leukemia

    Whole exome sequencing of 20 pediatric ALL patients yielded important insights into the genetic basis of ALL treatment failure. The findings may lead to early detection of the mutations that drive ALL relapse. (Jinghui Zhang, PhD, and Charles G. Mullighan, MBBS(Hons), MSc, MD)

     
     
    03/06/2015
    Genome reveals clues for better diagnosis and treatment of rare adrenal cancer

    St. Jude scientists identify key molecular events in pediatric adrenocortical tumors. The findings could help clinicians identify most malignant subtypes and lead to better treatment.

     
     
    04/06/2014
    For brain tumor patients, age matters

    Scientists at St. Jude Children’s Research Hospital have more evidence that age matters when it comes to the devastating brain tumors called high-grade gliomas (HGGs).

     
     
    04/06/2014
    Gene sequencing project discovers mutations tied to deadly brain tumors in young children

    St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project offers new leads to improved outcomes for children with high-grade glioma brain tumors; particularly youngest patients. (Suzanne Baker, PhD, and Jinghui Zhang, PhD)

     
     
    04/03/2014
    Tumor suppressor gene TP53 mutated in 90 percent of most common childhood bone tumor

    St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project finds TP53 gene is altered in nearly all osteosarcomas; results help explain how tumors withstand radiation therapy. (Michael Dyer, PhD, and Jinghui Zhang, PhD)

     
     
    02/19/2014
    Gene sequencing project discovers common driver of a childhood brain tumor

    St. Jude Children’s Research Hospital -Washington University Pediatric Cancer Genome Project identifies the most common genetic alteration yet in the brain tumor ependymoma; results offer clues for fighting other cancers. (Richard Gilbertson, MD, PhD, David Ellison, MD, PhD, Jinghui Zhang, PhD)

     
     
    02/19/2014
    Brain tumor culprit caught

    A hunt through billions of pieces of genetic information uncovers new clues on treatments for childhood ependymoma.

     
     
    01/02/2014
    The Treasure Seekers

    Scientists unearth genes driving a childhood brain tumor.

     
     
    04/08/2013
    Next-Generation Discoveries

    The Pediatric Cancer Genome Project uncovers the genetic mutations that give rise to cancer.

     
     
    01/24/2013
    Gene sequencing project mines data once considered 'junk' for clues about cancer

    St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project takes new approach to measuring the repetitive DNA at the end of chromosomes and opens new window on mechanisms fueling cancer. (Jinghui Zhang, PhD)

     
     
    07/09/2012
    Revealing the Secrets of the Genome

    Pediatric Cancer Genome Project scientists begin to uncover treasures.

     
     
    10/03/2011
    The Quest for CREST

    Scientists working on the Pediatric Cancer Genome Project develop a powerful new tool to pinpoint the structural variations that give rise to childhood cancers.

     
     
    06/12/2011
    Researchers improve method for finding genetic mistakes that fuel cancer

    St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project scientists pioneer way to find more chromosomal aberrations in tumors; results likely to advance understanding of cancer