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Brain Tumor : Intracranial ependymoma
Ependymoma is a type of cancer that occurs in the brain and spinal cord. The current standard of treatment for newly diagnosed ependymoma includes surgery to remove as much of the tumor as possible followed by radiation therapy.
Recent studies of young children have shown that chemotherapy (anti-cancer drug therapy) can help shrink or get rid of ependymoma and may make it easier for surgeons to remove the tumor.
The goal of this study is to find out if alternative treatments for ependymoma are available, including surgery followed by observation, surgery followed by chemotherapy, possible second surgery followed by radiation and chemotherapy. Patients with favorable pathology and tumor location in the upper part of the brain will undergo observation only following surgery. All other patients enrolled will receive 7 weeks of chemotherapy followed by three options depending on the results from the post induction MRI imaging (details below).
In general, this study aims to determine the effects of surgery, radiation therapy and chemotherapy on learning, thinking, hearing and the production of hormones.
Thomas Merchant, DO,PhD
St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105 USA
Phone: 901-595-3604 or 901-595-3596
Tabatha E. Doyle, RN
Coordinator, Brain Tumor Program
For the current eligibility status of this clinical study, patient’s family, relatives and/or referring physicians may contact St. Jude Children’s Research Hospital at (901) 595-4599 or (901) 595-2544.
The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.