Non-Therapeutic Protocol

XPD12-077 (BMTPE3): Cognitive, Academic and Psychosocial Functioning In Long-Term Survivors of Pediatric Stem Cell Transplantation

Type of Protocol/Clinical Study

Associated Stem Cell Transplant Studies


Advances in pediatric stem cell transplantation (SCT) have resulted in improved survival and prompted increased attention to the potential late side effects of this procedure. Past studies have shown generally stable cognitive (thinking) function in the first 5 years after transplant, with little evidence of significant problems. However, there has been almost no research done to study cognitive function long –term (> 5 years after transplant). In this study, researchers will evaluate large number long-term survivors of SCT using measures of intelligence, academic achievement, and specific cognitive functions such as attention, working memory and processing speed.

Researchers will also evaluate people who did not have SCT or other serious illnesses but are similar to the group of SCT survivors in age, gender and other factors. They will compare what they learned from both groups to see if they can understand more about the possible side effects of SCT on survivor’s thinking, learning abilities, and school performance.



Inclusion Criteria for the participant:

Exclusion Criteria:

Inclusion Criteria for the control (people who did not have SCT or other serious illnesses):

Principal Investigator

Sean Phipps, PhD

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