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    Zambetti: News Releases & Feature Stories

    Genome reveals clues for better diagnosis and treatment of rare adrenal cancer

    St. Jude scientists identify key molecular events in pediatric adrenocortical tumors. The findings could help clinicians identify most malignant subtypes and lead to better treatment.

    The hunt for Puma

    Nine-year-old Matthew Fox doesn’t talk much about the fact that he was found to have cancer when he was 4 years old. His mother, Freda, says most people have a hard time believing that the third-grader battled Burkitt lymphoma, a cancer in which immune cells called B lymphocytes turn malignant and proliferate uncontrollably.

    Protective “suicide protein” found to be thwarted in lymphoma

    St. Jude investigators have found that a protein called Puma, which normally protects the body by triggering cancer cells to commit suicide through a process called apoptosis, is suppressed in Burkitt lymphoma.

    Small change in gene mutation has big effect

    The discovery of an unexpected mutation in a patient supports researchers' belief that different mutations in the same cancer preventing gene--p53--can have vastly different medical consequences.

    Reactivating a cancer-killing protein

    St. Jude researchers are part of a team that has synthesized one of the body's most important defenses against the development of tumors.

    PUMA stalks cancer cells

    Proof that PUMA stalks cancer cells solves a long-standing mystery of the anti-cancer role of p53

    Following the Clues

    Why are children in southern Brazil more susceptible to a rare type of cancer than children in other parts of the world? St. Jude researchers and clinicians spend more than a decade unraveling the mystery.