Bone Marrow Transplant

Department of Bone Marrow Transplantation & Cellular Therapy

Chair

Wing H. Leung, MD, PhD


Departmental Focus

The mission of the Department of Bone Marrow Transplantation and Cellular Therapy at St. Jude Children’s Research Hospital is to provide outstanding care for all patients who need a hematopoietic stem cell / bone marrow transplant and to improve patient outcomes through research and staff education.

St. Jude pioneered mismatched transplants and NK cell therapy, thus providing a platform to perform life-saving transplants in patients without a matched donor or in patients with chemotherapy-refractory disease. The Department strives to perform cutting-edge laboratory and clinical research, particularly in the areas of immunogenetics, cellular therapy, transplant tolerance, immune reconstitution, infection control, and survivorship. Formal programs are offered for graduate studies or fellowships in postdoctoral research or clinical transplant.

Under the Bone Marrow Transplantation Program at St. Jude, one of the largest pediatric programs in the world, a total of more than 2,000 transplants have been performed since 1982. Our patients are newborns, infants, children, adolescents and young adults who have a malignant or nonmalignant life-threatening disorder that is treatable with a hematopoietic stem cell / bone marrow transplant with autologous cells or allogeneic cells.

Children with life-threatening illnesses who are undergoing hematopoietic stem cell / bone marrow transplant require highly specialized resources and experienced staff, such as those available at St. Jude, to meet their physical, psychological, social, and developmental needs. At St. Jude, a multidisciplinary team of health care professionals provides advanced treatment, and all of our patients are enrolled on clinical research protocols that are designed to give patients the best possible chances of survival with the fewest possible complications when they undergo the transplantation procedure.

The Transplant Program at St. Jude is approved by the Children's Oncology Group (COG), the National Marrow Donor Program (NMDP), the Pediatric Blood and Marrow Transplant Consortium, and the Center for International Blood and Marrow Transplant Research (CIBMTR). The Program is certified by the Foundation for Accreditation of Cellular Therapy (FACT).


Contact Us

Bone Marrow Transplantation & Cellular Therapy
MS 1130, Room I-3310
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678

Email: wing.leung@stjude.org
Phone: (901) 595-2554
FAX: (901) 595-7944

Preferred contact method: email


Faculty

Lea C. Cunningham, MD  Development of novel immunomodulatory therapies

Mari H. Dallas, MD  Cord blood transplantation and immune reconstitution

Christine M. Hartford, MD  Clinical pharmacology and pharmacogenomics

William E. Janssen, PhD  Therapeutic use of intact cell products

Wing H. Leung, MD, PhD  NK cell & stem cell transplantation, late effects

Asha B. Pillai, MD  Immunobiology of alloregulation, engraftment, & GVHD

David R. Shook, MD   Transplantation for solid tumors; cellular therapy

Ashok Srinivasan, MD  Infections in the immune-compromised host

Brandon Triplett, MD  Hematopoietic cell transplantation