Disease Information

Infectious Diseases: Infections in Immunocompromised Patients

Alternate Names: None


Most patients at St. Jude Children’s Research Hospital have weakened immune systems. St. Jude's goal is developing effective ways of preventing serious infections among children whose immune systems are weakened by cancer chemotherapy or bone marrow transplantation. The following information focuses primarily on patients who become immunocompromised as a result of treatment for their disease.

Immunocompromised patients are susceptible to bacterial, fungal, and viral infections that healthy immune systems usually conquer. They are also susceptible to common infections of childhood. Often, the symptoms tend to be worse.

There are several reasons why powerful treatments such as chemotherapy and radiation weaken the immune system.

Influencing Factors

Clinical Features and Symptoms

Treatment Strategies

Prevention techniques

Current Research


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