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Fabio Demontis, PhD

Fabio Demontis, PhD

Assistant Member, St. Jude Faculty


Developmental Neurobiology


Developmental Biology

Contact Information

Fabio Demontis, PhD
Developmental Neurobiology
MS 324, Room D2038C
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Phone: (901) 595-5444
FAX: (901) 595-7641


Laurea (MSc) - Medical School, University of Milano, Italy
PhD - Max Planck Institute for Cell Biology and Genetics, Dresden, Germany
Postdoctoral studies - Harvard Medical School/HHMI, Boston, Massachusetts

Honors & Awards

Research Interests

Selected Publications

Patel VK, Demontis F. GDF11/Myostatin and aging. Aging May;6(5):351-352, 2014.

Demontis F, Patel VK, Swindell WR, Perrimon N. Intertissue control of the nucleolus via a myokine-dependent longevity pathway. Cell Reports June 12;7(5):1481-1494, 2014.

Piccirillo R, Demontis F, Perrimon N, Goldberg AL. Mechanisms of muscle growth and atrophy in mammals and Drosophila. Developmental Dynamics June;7(5):1-14, 2014.

Hunt LC, Demontis F. Whole-mount immunostaining of Drosophila skeletal muscle. Nature Protocols Dec;8(12):2496-501, 2013.

Demontis F, Piccirillo R, Goldberg AL, Perrimon N. The influence of skeletal muscle on systemic aging and lifespan. Aging Cell Dec;12(6):943-9, 2013.

Demontis F, Piccirillo R, Goldberg AL, Perrimon N. Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models. Disease Modelels & Mechanisms Nov;6(6):1339-52, 2013.

Katewa SD, Demontis F, Kolipinski M, Hubbard A, Gill MS, Perrimon N, Melov S, Kapahi P. Intra-myocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Cell Metabolism Jul 3;16(1):97-103, 2012.

Demontis F, Perrimon N. FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell Nov 24;143(5):813-25, 2010.

Demontis F, Perrimon N. Integration of InR/FOXO signaling and dMyc activity during muscle growth regulates body size. Development Mar;136(6):983-93, 2009.

Last updated: June 2014