Hematological Disorders Protocols / Clinical Studies

For information on these and other studies, referring physicians may e-mail protocolinfo@stjude.org or call our toll free physician referral line, 1-888-226-4343. If you are not a physician, please e-mail info@stjude.org for information on St. Jude studies.


A Phase I Trial of Bendamustine in Combination with Clofarabine and Etoposide in Pediatric Patients with Relapsed or Refractory Hematologic Malignancies

For: Relapsed or refractory hematologic malignancies


A Pilot Feasibility Study of Gene Transfer for X-linked Severe Combined Immunodeficiency in Newly Diagnosed Infants Using a Self-Inactivating Lentiviral Vector to Transduce Autologous CD34+ Hematopoietic Cells

For: X-linked Severe Combined Immunodeficiency (SCID-X1)


Massive Iron Deposit Assessment Study

For: Iron overload (non-therapeutic)


A Phase II Study of Bortezomib and Vorinostat in Patients with Refractory or Relapsed MLL Rearranged Hematologic Malignancies

For: Relapsed or refractory Acute Lymphoblastic Leukemia (ALL), Biphenotypic/Mixed Lineage Leukemia (MLL), or Acute Myeloid Leukemia (AML)


A Phase I/II Study of the Selective Inhibitor of Nuclear Export Selinexor (KPT-330) in Combination with Fludarabine and Cytarabine in Pediatric Patients with Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

For: Relapsed or refractory leukemia or hematologic malignancies


Non St. Jude Protocols


Hemophilia Inhibitor Research Study Phase III

For: Hemophilia (non-therapeutic)


A Phase 3 Double-Blind, Randomized, Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients with Sickle Cell Disease

For: Sickle cell disease