Non-Therapeutic Protocol

CCL1034: CCL1034/Impact of Cleansing with Chlorhexidine Gluconate (CHG) on Reducing Central Line Associated Bloodstream Infection (CLABSI) and Acquisition of Multi-Drug Resistant Organisms (MDRO) In Children with Cancer or Those Receiving Allogeneic Hematopoietic Cell Transplantation (HCT) (ACL1034)

Type of Protocol/Clinical Study

Associated Infectious Diseases Studies : Cancer or allogeneic hematopoietic cell transplantation


In this study, we want to see if using CHG cleansing cloths can help prevent central line associated bloodstream infections (CLA-BSIs). To test this we will give participants a cleansing cloth that either contains CHG or does not contain CHG and observe how well each one prevents CLA-BSI.

Preventing CLA-BSI is important for the following reasons:

CHG cloths have been researched in adult population. These studies have shown that use of CHG, either in cloths or as a liquid wash, helped reduce the chances of getting CLA-BSIs in patients with central lines. These studies also showed that the use of CHG reduced the chance of getting bacteria (germs) resistant to multiple antibiotics. However, the use of CHG cloths is experimental in children and adolescents with cancer.


Eligibility criteria, among others, include:

For the current eligibility status of this clinical study, referring physicians must contact St. Jude Children's Research Hospital at 1-866-2ST-JUDE (1-866-278-5833).

Principal Investigator

Gabriela Marón, MD

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.