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    Gilbertson: News Releases & Feature Stories

    First cancer-promoting oncogenes discovered in rare brain tumor of children and adults

    Researchers have identified three genes that play a pivotal role in the brain tumor choroid plexus carcinoma (CPC), a discovery that lays the groundwork for more effective treatment of this rare, often fatal cancer. (Richard J. Gilbertson, MD, PhD)

    St. Jude Children’s Research Hospital renewed as NCI-designated Comprehensive Cancer Center

    St. Jude Comprehensive Cancer Center receives “exceptional” score from National Cancer Institute—highest rating awarded to cancer centers.

    Gene sequencing project discovers common driver of a childhood brain tumor

    St. Jude Children’s Research Hospital -Washington University Pediatric Cancer Genome Project identifies the most common genetic alteration yet in the brain tumor ependymoma; results offer clues for fighting other cancers. (Richard Gilbertson, MD, PhD, David Ellison, MD, PhD, Jinghui Zhang, PhD)

    Brain tumor culprit caught

    A hunt through billions of pieces of genetic information uncovers new clues on treatments for childhood ependymoma.

    Solving the Puzzle

    Scientists explore subtypes of a deadly brain tumor.

    Gene sequencing project identifies potential drug targets in common childhood brain tumor

    St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project lifts lid on the most aggressive subtype of medulloblastoma and finds genes that cooperate in tumor development. (Dr. Richard Gilbertson)

    Writing the Next Chapter

    For many years, St. Jude researchers have been investigating the connection between genetics and pediatric cancer. Those approaches continue to have dramatic implications for clinical care.

    New strategy likely to speed drug development for rare cancers

    Research led by St. Jude Children’s Research Hospital investigators used a pioneering approach to drug development and identified dozens of potential new treatments of ependymoma, a rare tumor of the brain and spinal cord.

    St. Jude Children's Research Hospital appoints Richard Gilbertson, M.D., Ph.D., to lead its Comprehensive Cancer Center

    Noted researcher will direct the country's only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children.

    Right on

    Sometimes two wrongs do, in fact, make a right

    Different origins discovered for medulloblastoma tumor subtypes

    International effort led by St. Jude Children’s Research Hospital scientists is expected to fuel development of targeted therapies and aid the search for unique combinations of cells and mutations that lead to other cancers

    St. Jude scientists develop new genomics-based approach to understand the origin of cancer subgroups

    Scientists have long recognized that cancers may look the same under the microscope, but carry different mutations, respond differently to treatment and result in vastly different outcomes for patients.

    Molecular marker identifies normal stem cells as intestinal tumor source

    St. Jude scientists have answered a central question in cancer biology: whether normal stem cells can give rise to tumors.

    Coming to the table for discovery

    Whenever family and friends are invited to your home, chances are the evening will end with everyone lingering in the kitchen. Perhaps someone has a warm pot of coffee to share, a story or a hearty laugh. Whatever the attraction, the heart of the home beats strongest when everyone joins together. At St. Jude Children’s Research Hospital, the Chemical Biology and Therapeutics (CBT) department serves a similar role.

    Gilbertson receives support for brain tumor research

    Richard Gilbertson, MD, PhD, has received almost $1 million in support from two foundations that support brain tumor research.

    Brain tumor researchers find their "niche"

    St. Jude researchers have found a vulnerable spot in brain tumors they are trying to exploit to improve the treatment of these cancers and prevent tumors from returning.

    Tumor Wars

    St. Jude researchers launch a counterattack on pediatric cancer using molecular-targeted therapy. As scientists learn more about the human genome and specific genetic mutations, they are finding new strategies to ambush the enemy.

    Powerful new tool for studying brain development

    The mouse Brain Gene Expression Map at St. Jude shows where and when genes influence development of the brain and helps researchers study links between gene mutations and cancers.

    Technique could speed new treatments for medulloblastoma

    The discovery that expression of specific genes can accurately report the presence of mutations in biochemical pathways within medulloblastoma cells could speed development of more effective and less toxic treatments.

    Touchdown: Neurobiology and Brain Tumor Program

    Thanks to the St. Jude Neurobiology and Brain Tumor Program, victory is within reach for kids with medulloblastoma.

    Discovery may mean better ependymoma treatments

    Ependymomas that occur in different parts of the central nervous system appear to arise from different subpopulations of stem cells. The discovery explains why some identical-looking ependymomas are actually distinctly different diseases...

    Improving treatment of medulloblastoma

    Clinical researchers are getting closer to an international clinical trial to improve guidelines for treatment of medulloblastoma.