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Goulian Kang, PhD

Guolian Kang, PhD

Assistant Member, St. Jude Faculty

Departments

Biostatistics

Contact Information

Guolian Kang, PhD
Biostatistics
MS 768, Room R6008
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Email: guolian.kang@stjude.org
Phone: (901) 595-2666
FAX: (901) 595-8843

Education

PhD - Institute of Systems Science, Chinese Academy of Sciences, China
MS - Qufu Normal University, China
BS - Qufu Normal University, China


Research Interests


Selected Publications

Srinivasan A, Wang WC, Gaur A, Smith T, Gu Z, Kang G, Leung W, Hayden R. Prospective detection of respiratory pathogens in children with sickle cell disease and acute respiratory illness. Pediatric Blood and Cancer 61(3): 507-511, 2014.

Srinivasan A, Panetta JC, Cross S, Pillai A, Triplett BM, Shook DR, Dallas MH, Hartford C, Sunkara A, Kang G, Jacobsen J, Choi J, and Leung W. Phase I study of the safety and pharmacokinetics of plerixafor in children undergoing a second allogeneic hematopoietic stem cell transplantation for relapsed or refractory leukemia. Biology Blood and Marrow Transplantation 20(8):1224-1228, 2014.

Kang G*#, Bi W*, Zhao Y#, Zhang J, Yang JJ, Xu H, Reilling MV, Loh ML, Hunger SP, Pounds S, Cheng C. A new system identification approach to identify genetic variants in sequencing studies for a binary phenotype. Hum Hered 78:104-116, 2014.

Kang G#, Jiang B, Cui Y. Gene-based genomewide association analysis: a comparison study. Current Genomics 14(4): 250-255, 2013.

Srinivasan A, Gu Z, Smith T, Morgenstern M, Sunkara A, Kang G, Srivastava GK, Gaur AH, Leung W, Hayden RT. Prospective detection of respiratory pathogens in symptomatic children with cancer. The Pediatric Infectious Disease Journal 32(3): e99-e104, 2013.

Bari R, Rujkijyanont P, Sullivan E, Kang G, Turner V, Gan K, Leung W. Effect of donor KIR2DL1 allelic polymorphism on the outcome of pediatric allogeneic hematopoietic stem cell transplantation. Journal of Clinical Oncology 31(30): 3782-3790, 2013. *Reported by ScienceDaily in September, 2013 http://www.sciencedaily.com/releases/2013/09/130916162033.htm

Benavente CA, McEvoy JD, Finkelstein D, Wei L, Kang G, Wang YD, Neale G, Ragsdale S, Valentine V, Bahrami A, Temirov J, Pounds S, Zhang J, Dyer MA. Cross-species genomic and epigenomic landscape of retinoblastoma. Oncotarget 4(6): 844-859, 2013.

Rujkijyanont P, Morris C, Kang G, Gan K, Hartford C, Triplett B, Dallas M, Srinivasan A, Shook D, Pillai A, Pui CH, Leung W. Risk-adapted donor lymphocyte infusion based on chimerism and donor source in pediatric leukemia. Blood Cancer Journal 3:e137, 2013.

Kang G, Lin D, Hakonarson H, Chen J. Two-stage extreme phenotype sequencing design for discovering and testing common and rare genetic variants: efficiency and power. Human Heredity 73:139-147, 2012.

Chen J*, Kang G*, VanderWeele T, Zhang C, Mukherjee B. Efficient designs of gene-environment interaction studies: implications of Hardy-Weinberg equilibrium and gene-environment independence. Statistics in Medicine 31(22):2516-2530, 2012.

Gao G*, Kang G*, Wang J, Qin H, Jiang B, Li Q, Chen W, Liu N, Allison DB. A generalized sequential Bonferroni procedure using smoothed weights for genome-wide association studies incorporating information on Hardy-Weinberg disequilibrium among cases. Human Heredity 73:1-13, 2012.

Yeung EH, Zhang C, Chen J, Bowers K, Hu FB, Kang G, Qi L. Polymorphisms in the Neuropeptide Y gene and the risk of obesity: findings from two prospective cohorts. Journal of Clinical Endocrinology and Metabolism 96:E2055-2062, 2011.

Jiang B, Zhang X, Zuo Y, Kang G**. A powerful truncated tail strength method for testing multiple hypotheses in a dataset. Journal of Theoretical Biology 277:67-73, 2011.

Kang G, Gao G, Shete S, Redden DT, Chang B-L, Rebbeck TR, Barnholtz-Sloan JS, Patterson N, Pajewski NM, Allison DB. Capitalizing on admixture in genome-wide association studies: A two-stage testing procedure and application to height in African-Americans. Frontiers in Genetics 2:11, 2011. doi: 10.3389/fgene.2011.00011

Zuo Y, Kang G. A mixed two-stage analysis for detecting interacting genes in genomewide association studies. Journal of Theoretical Biology 262:576-583, 2010.

Kang G, Ye K, Allison DB, Liu N, Gao G. Weighted multiple hypothesis testing procedures. Statistical Applications in Genetics and Molecular Biology 8(1),Article 23, 2009.

Kang G, Yue W, Zhang J, Cui Y, Zuo Y, Zhang D. An entropy-based approach for testing genetic epistasis underlying complex diseases. Journal of Theoretical Biology 250:362-374, 2008. (Awarded 2009 best paper in the area of statistical genetics from Science Unbound Foundation http://www.scienceunboundfoundation.org/2009.html)

Cui Y, Kang G, Sun K, Qian M, Romero R, Fu W. Gene-centric genome-wide association study via entropy. Genetics 179:637-650, 2008. (Research highlighted in Nature Review Genetics (2008, Vol. 9 No. 6). http://www.nature.com/nrg/journal/v9/n6/full/nrg2387.html)

Kang G, Yue W, Zhang J, Huebner M, Zhang H, Ruan Y, Lu T, Ling Y, Zuo Y, Zhang D. Two-stage designs to identify the effects of SNP combinations on complex diseases. Journal of Human Genetics 53:739-746, 2008.

Kang G, Li S, Zhang J. Entropy-based models for interpreting life systems in traditional Chinese medicine. Evidence-based Complementary and Alternative Medicine 5(3):273-279, 2008. (Reported by the international media of “International Adaptogens” (Venezuela). http://www.adaptogeno.com/svms/noticias/noticia367.asp in 10/2008. Included in the monograph of “Transg´enicos” (Cuba).)

Kang G, Zuo Y. Entropy-based joint analysis for two-stage genomewide association studies. Journal of Human Genetics 52:747-756, 2007.

Yue W*, Kang G*, Zhang Y, Qu M, Tang F, Han Y, Ruan Y, Lu T, Zhang J, Zhang D. Association of DAOA polymorphisms with schizophrenia and clinical symptoms or therapeutic effects. Neurosci Lett 416:96-100, 2007.

Yue W, Kang G, Zhang H, Tang F, Qu M, Han Y, Yan J, Ruan Y, Lu Y, Zhang D. Association study between schizophrenia and NRG1,G72,RGS4 polymorphisms. Chin J of Behavioral Med Sci 16:418-820, 2007. (In Chinese)

Yue W, Liu Z, Kang G, Yan J, Tang F, Ruan Y, Zhang J, Zhang D. Association of G72/G30 polymorphisms with early-onset and male schizophrenia. NeuroReport 17(18):1899-1902, 2006.

Kang G, Meng F. Oscillation criteria for second-order quasi-linear neutral difference equations. Journal of Engineering Mathematics 23(1):923-926, 2006.

Kang G. Oscillation criteria for second-order half-linear neutral difference equations. Journal of Mathematical Research and Exposition 26(2):247-252, 2006.

Kang G. Oscillation criteria for second-order nonlinear difference equation with “summation small” coefficient. Bull Korean Math Society 42(2):245-256, 2005.

Kang G, Zhang H. Oscillation criteria of solutions of nonlinear difference equations of second order. Annals of Differential Equations 20(1):41-48, 2004.

(*Co-first author, **Corresponding author)

Last update: September 2014