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The Medical Terminology and Drug Database is provided as a convenience to our users. Definitions are provided by the National Cancer Institute, U.S. National Institutes of Health, for informational purposes only. This list is updated monthly.
K
KGF
Keratinocyte growth factor. A substance that stimulates the growth of epithelial cells that line the surface of the mouth and intestinal tract. There are several forms of KGF. Recombinant human KGF (rHuKGF) is being studied in the prevention of graft-versus-host disease (GVHD) that may occur after tissue transplantation, and in the treatment of mucositis caused by chemotherapy and radiation therapy. rHuKGF is also called palifermin.
KOS-862
A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called mitotic inhibitors and epothilones. Also called epothilone D.
KPS
Karnofsky Performance Status. A standard way of measuring the ability of cancer patients to perform ordinary tasks. The
KRN5500
An anticancer drug that belongs to a family of drugs called antitumor antibiotics. It is an anthracycline.
KRN7000
A drug being studied in the treatment of cancer. It is a biological response modifier that belongs to the family of drugs called glycosphingolipids or agelasphins.
KSHV
Kaposi's sarcoma-associated herpesvirus. A type of herpesvirus that may cause Kaposi's sarcoma (a rare cancer that can cause skin lesions) and a type of lymphoma (cancer that begins in the lymph system), especially in patients who have a weak immune system. Also called human herpesvirus 8 (HHV8).
KW2189
A semisynthetic anticancer drug that belongs to the family of drugs called antitumor antibiotics.
Kahler's disease
A type of cancer that begins in plasma cells (white blood cells that produce antibodies). Also called multiple myeloma, myelomatosis, or plasma cell myeloma.
Kahler�s disease
A type of cancer that begins in plasma cells (white blood cells that produce antibodies). Also called multiple myeloma, myelomatosis, or plasma cell myeloma.
Kaposi's sarcoma
A type of cancer characterized by the abnormal growth of blood vessels that develop into skin lesions or occur internally.
Kaposi�s sarcoma-associated herpesvirus
KSHV. A type of herpesvirus that may cause Kaposi's sarcoma (a rare cancer that can cause skin lesions) and a type of lymphoma (cancer that begins in the lymph system), especially in patients who have a weak immune system. Also called human herpesvirus 8 (HHV8).
Karnofsky Performance Status
KPS. A standard way of measuring the ability of cancer patients to perform ordinary tasks. The
Kinaret®
A substance that is used to treat rheumatoid arthritis, and is being studied in the treatment of cancer. Kinaret blocks the action of interleukin 1 (IL-1). It belongs to the family of drugs called interleukin receptor antagonists. Also called anakinra.
Kinaret®
A substance that is used to treat rheumatoid arthritis, and is being studied in the treatment of cancer. Kinaret® blocks the action of interleukin 1 (IL-1). It belongs to the family of drugs called interleukin receptor antagonists. Also called anakinra.
Klatskin tumor
Cancer that develops in cells that line the bile ducts in the liver, where the right and left ducts meet. It is a type of cholangiocarcinoma.
Klebsiella
A bacteria that frequently causes lung, urinary tract, intestinal, and wound infections.
Klinefelter's syndrome
A genetic disorder in males caused by having an extra X chromosome. Males with this disorder may have larger than normal breasts, a lack of facial and body hair, a rounded body type, and small testicles. They may learn to speak much later than other children and may have difficulty learning to read and write. Klinefelter's syndrome increases the risk of developing testicular cancer.
Krukenberg tumor
A tumor in the ovary caused by the spread of stomach cancer.
karenitecin
A drug being studied in the treatment of cancer. It belongs to a family of drugs called topoisomerase inhibitors. It is related to the anticancer drug camptothecin.
keloid
A thick, irregular scar caused by excessive tissue growth at the site of an incision or wound.
keratan sulfate
A glycosaminoglycan (a type of polysaccharide) found in cartilage and in the cornea of the eye.
keratinocyte growth factor
KGF. A substance that stimulates the growth of epithelial cells that line the surface of the mouth and intestinal tract. There are several forms of KGF. Recombinant human KGF (rHuKGF) is being studied in the prevention of graft-versus-host disease (GVHD) that may occur after tissue transplantation, and in the treatment of mucositis caused by chemotherapy and radiation therapy. rHuKGF is also called palifermin.
keratoacanthoma
A benign (noncancerous), rapidly growing skin tumor that usually occurs on sun-exposed areas of the skin and that can go away without treatment.
ketoconazole
A drug that treats infection caused by a fungus. It is also used as a treatment for prostate cancer because it can block the production of male sex hormones.
ketorolac
A drug that belongs to a family of drugs called nonsteroidal anti-inflammatory agents. It is being studied in cancer prevention.
keyhole limpet hemocyanin
KLH. One of a group of drugs called immune modulators, given as a vaccine to help the body respond to cancer.
kidney
One of a pair of organs in the abdomen. Kidneys remove waste from the blood (as urine), produce erythropoietin (a substance that stimulates red blood cell production), and play a role in blood pressure regulation.
kidney failure
A condition in which the kidneys stop working and are not able to remove waste and extra water from the blood or keep body chemicals in balance. Acute kidney failure happens suddenly (for example, after an injury) and may be treated and cured. Chronic kidney failure develops over years (related to high blood pressure or diabetes, for example) and cannot be cured. Total and permanent kidney failure is called end-stage renal disease (ESRD), and requires dialysis (process of cleaning the blood by passing it through a membrane or filter) or a kidney transplant.
killer cell
A white blood cell that attacks tumor cells and body cells that have been invaded by foreign substances.
kilogram
A measure of weight. A kilogram is equal to 2.2 pounds.
kretek
A cigarette made of a mixture of tobacco and clove.