St. Jude Children's Research Hospital - Latest News

Study tracks long-term challenges facing survivors of childhood CNS tumors

2009-07-01

The most comprehensive study yet of long-term survivors of childhood central nervous system (CNS) tumors details risks some survivors face decades after their diagnosis, prompting a renewed call for improved follow-up care.

Acute lymphoblastic leukemia, the most common childhood cancer, is curable without preventive cranial radiation

2009-06-24

Childhood acute lymphoblastic leukemia (ALL) can be successfully treated using a carefully personalized chemotherapy regimen without cranial radiation, investigators at St. Jude Children's Research Hospital have found. Such radiation of the brain was once a standard ALL treatment to prevent recurrence of the leukemia in the central nervous system (CNS).

Acute lymphoblastic leukemia, the most common childhood cancer, is curable without preventive cranial radiation

2009-06-24

Scientists clear hurdles to tap potential of natural killer cells

2009-06-24

Efforts to harness natural killer (NK) cells for cancer treatment advanced recently thanks to a St. Jude strategy that dramatically boosts production of the powerful, but rare immune component.

St. Jude scientist named Pew Scholar

2009-06-16

Charles Mullighan, MD, PhD, an assistant member in the Pathology Department at St. Jude Children’s Research Hospital, has been named a 2009 Pew Scholar in the Biomedical Sciences. He is the fourth St. Jude scientist honored.

St. Jude researchers find that MRI can replace biopsy for monitoring iron

2009-06-12

Nobody likes needles. So it’s good news that St. Jude researchers have found they can replace one big needle with a magnet. The needle is used to take a liver biopsy sample to measure the body’s iron level; and the magnet is the heart of a magnetic resonance imaging (MRI) machine.

Richard C. Shadyac Jr. named new ALSAC CEO

2009-06-11

Richard C. Shadyac Jr., who served this year as chairman/president of the ALSAC Board of Directors, will take the reins of ALSAC as chief executive officer on September 1. He succeeds interim CEO David L. McKee, who will continue to serve as chief operating officer.

St. Jude Classic brings big names and awareness for lifesaving mission

2009-06-08

The PGA TOUR’s FedExCup visits Memphis, Tennessee for this week’s St. Jude Classic. The tournament is celebrating its 52nd year with one of its strongest fields of golfers. The world’s No. 2 player, Phil Mickelson, will return to Memphis for the first time since 2001 to compete against top players such as Sergio Garcia, Camilo Villegas, Henrik Stenson, Padraig Harrington and defending St. Jude Classic champion Justin Leonard.

Scientists discover new insight into primate eye evolution

2009-06-05

Researchers comparing the fetal development of the eye of the owl monkey with that of the capuchin monkey have found that only a minor difference in the timing of cell proliferation can explain the multiple anatomical differences in the two kinds of eyes.

Win the house of your dreams and support the lifesaving work of St. Jude

2009-06-04

Take a chance on winning the house of your dreams and help support the patients of St. Jude Children's Research Hospital. This weekend, 12 fantastic homes, valued between $300,000 and $700,000, are being given away in select cities during the St. Jude Dream Home^® Giveaway.

Mutant genes identified in high-risk childhood leukemias

2009-06-02

A research team has pinpointed a new class of gene mutations, which identify cases of childhood acute lymphoblastic leukemia (ALL) that have a high risk of relapse and death.

Kappa Alpha Psi honored for Sunday of Hope program

2009-05-27

On May 18, Kappa Alpha Psi’s Sunday of Hope turned in to a Celebration of Hope at St. Jude Children’s Research Hospital as members of Kappa Alpha Psi and top fundraising churches joined St. Jude families for a special ceremony where Kappa Alpha Psi was presented with a commemorative plaque in the Patient Care Center.

Study shows childhood cancer survivors exercise less

2009-05-26

In a new study of adults who survived cancer as children, St. Jude researchers have found that many survivors lead sedentary lifestyles and are more likely to be less physically active than their siblings.

Mutant genes in high-risk childhood leukemias identified

2009-05-19

Results of collaborative study could lead to development of new diagnostic tools and a new therapeutic target in high-risk disease.

New insight into primate eye evolution

2009-05-18

St. Jude study of the nocturnal owl monkey suggests that evolution needed only a few genetic changes to profoundly alter eye anatomy

Taming dangerous lung inflammation in influenza

2009-05-14

One of the most threatening complications of influenza stems not from the virus itself, but from the overreaction of the immune system. This overreaction can cause persistent lung inflammation that lasts long after the virus has been quelled.

Thanks for making St. Jude No. 1 in Target's Bullseye Gives campaign

2009-05-10

Thanks to all of the St. Jude Children's Research Hospital supporters who took time to vote in Target's Bullseye campaign on Facebook^®. Your votes helped make St. Jude the No. 1 charity in the campaign.

Adding a new piece to the puzzle of chromosomal segregation

2009-05-08

Every cell in the body arises from the process of cell division—an intricate molecular process in which a cell precisely copies its gene-containing chromosomes and segregates them into identical parcels that migrate into the two new daughter cells. Malfunction of this segregation machinery can have profound consequences.

St. Jude scientists help develop a vaccine for influenza A (H1N1)

2009-05-01

As the world watches the developing story of the influenza A (H1N1) outbreak, St. Jude Children’s Research Hospital is working collaboratively with other research centers to help develop an effective vaccine.

St. Jude scientists help develop a vaccine for influenza A (H1N1)

2009-05-01

Study holds promise for first targeted treatment of common brain tumor

2009-05-01

Scientists have found evidence suggesting that small-molecule drugs could offer the first effective chemotherapy for childhood low-grade astrocytomas, improving the prognosis for hundreds of children with the disease.

New insights found into engineering immune cells to fight cancer, infection

2009-04-24

Immunologists have made great strides in enlisting the body’s own immune cells to fight cancers and infections.

Benihana celebrates Japanese Children's Day by supporting St. Jude

2009-04-21

Benihana restaurants will celebrate Kodomo no Hi, or Children’s Day on May 5 by donating 100 percent of the proceeds of all children’s meals served that day to St. Jude Children’s Research Hospital. The one-day benefit is part of the famed teppanyaki restaurant company’s “Children Helping Children” program.

Mickelson, Garcia and Villegas commit to play in the St. Jude Classic

2009-04-20

Phil Mickelson, Sergio Garcia and Camilo Villegas, three of the world’s top golfers, have committed to play in the 2009 St. Jude Classic.

St. Jude Acute Lymphoblastic Leukemia Team recognized with prestigious science award

2009-04-14

Scientists at St. Jude Children’s Research Hospital who represent the interdisciplinary team studying acute lymphoblastic leukemia (ALL) have been recognized by the American Association for Cancer Research (AACR) with the AACR Team Science Award.

Aaron Curry invites patient to NFL Draft

2009-04-14

Wake Forest University senior linebacker Aaron Curry, a top prospect in the 2009 NFL Draft, visited St. Jude on April 13 and invited patient Bryson to join him in New York for a once-in-a-lifetime experience, including joining the future NFL star in the green room of Radio City Music Hall as he awaits his selection in the draft.

Scholastic and St. Jude team up to fight cancer

2009-04-14

St. Jude is proud to announce that Scholastic Inc. has teamed with the St. Jude Math-A-Thon® to bring the Math-A-Thon program to a new and exciting level for the 2009 -10 school year.

Eye cells believed to be retinal stem cells are misidentified

2009-04-09

Cells isolated from the eye that many scientists believed were retinal stem cells are, in fact, normal adult cells, investigators at St. Jude have found. If retinal stem cells could be obtained, they might provide the basis for treatments to restore sight to millions of people with blindness caused by retinal degeneration.

Tiny genetic materials identified as key players in causing medulloblastoma

2009-04-07

Researchers at St. Jude have demonstrated for the first time that tiny molecules called microRNAs participate in the initiation and progression of one form of human medulloblastoma, the most common malignant brain cancer in children.

Cell discovery might lead to therapies to shrink death toll in flu pandemic

2009-04-03

St. Jude researchers have discovered a key factor of fatal influenza virus infection that suggests a possible new way to treat the disease and to greatly reduce the death toll of a potential worldwide pandemic like the 1918 Spanish flu.

Catie’s final wish gives hope to other children

2009-04-03

Near the end of her fight against a rare spinal tumor, Catie made an extraordinary final wish, not for herself, but for the other patients of St. Jude Children's Research Hospital. Catie's wish was to raise enough funds to cover the care for all the children of St. Jude on what would have been her eighth birthday, April 23. Donate today to honor Catie's wish.

Grizzlies auction to support Memphis Grizzlies House

2009-04-01

From April 1 – 10, Grizzlies fans can visit the Grizzlies auction page on NBA.com and bid on a variety of one-of-a-kind items, including a Grizzlies team captain experience, opportunities to sit on press row, work out with the Grizzlies trainer or receive an autographed basketball.

St. Jude Intensive Care Unit honored with prestigious critical care award

2009-03-31

Nurses and staff in the Intensive Care Unit (ICU) at St. Jude Children’s Research Hospital have been recognized by the American Association of Critical-Care Nurses (AACN) with the Beacon Award for Critical Care Excellence. The award recognizes the nation’s top adult critical care, pediatric critical care and progressive care units.

Eye cells believed to be retinal stem cells are misidentified (news release)

2009-03-30

Cells isolated from the eye that many scientists believed were retinal stem cells are, in fact, normal adult cells, investigators at St. Jude Children's Research Hospital have found.

St. Jude researcher named Howard Hughes Early Career Scientist

2009-03-26

Michael Dyer, a faculty member at St. Jude Children's Research Hospital, has been tapped as one of the nation’s leading scientists by the Howard Hughes Medical Institute.

New insights into the cell’s cancer-suppressing machinery

2009-03-25

The p53 protein plays an immensely important role in protecting the body from cancer. Dubbed the cell’s guardian of the genome, p53 is constantly poised to detect potentially tumor-causing DNA damage.

New cancer treatment drug combo shows promise

2009-03-23

Oncologists frequently use combinations of chemotherapy drugs as a knockout punch against tumors. The strategy has proven successful because it aims to jam the machinery of cancer cells in ways that are synergistic—fighting cancers more effectively than the individual drugs could alone.

Jennifer Aniston-narrated book to benefit St. Jude

2009-03-17

Actress Jennifer Aniston and her father, actor John Aniston, narrate the latest adventure of the fluffy, cuddly lamb Loukoumi, the sale of which will benefit St. Jude Children’s Research Hospital.

Key medulloblastoma brain cancer genes pinpointed

2009-03-10

Scientists at St. Jude have generated new models of medulloblastoma tumors by inactivating different DNA repair pathways, specifically in the brain.

Life-and-death protein regulates immune system’s “emergency team”

2009-03-02

White blood cells called neutrophils and macrophages are the first responders of the immune system. They serve as the first line of defense against invading microbes—identifying them, engulfing them and eliminating them.

Study finds more effective treatment for pneumonia following influenza

2009-02-25

Scientists at St. Jude have demonstrated an extremely effective treatment for bacterial pneumonia following influenza.

Pinpointing a high-risk leukemia promises better treatment

2009-02-19

For the first time, St. Jude researchers have identified a subtype of acute T-lymphoblastic leukemia (T-ALL) that is resistant to standard chemotherapy. They are planning to use this new insight to diagnose the disease in children with the subtype and to use bone marrow transplants to more effectively treat the disease.

Study shows how defective DNA repair triggers two neurological diseases

2009-02-17

St. Jude scientists have teased apart the biological details distinguishing two related neurological diseases—ataxia telangiectasia-like disease (ATLD) and Nijmegen breakage syndrome (NBS).

Tennis stars step to the service line for St. Jude

2009-02-17

Many of the top tennis players in the world are in Memphis, Tennessee, this week for the Regions Morgan Keegan Championships and the Cellular South Cup benefiting St. Jude. Former champions Andy Roddick and Tommy Haas are among a field of top contenders who are competing for the RMK title.

Childhood cancer survivors show inadequate screening for breast cancer

2009-02-12

Even though women treated for childhood cancers with chest radiation suffer a high risk of breast cancer, they are far less likely to begin recommended early mammogram screening than they should, researchers found.

Memphis Grizzlies House celebrates five years of serving St. Jude families

2009-02-09

Memphis Grizzlies players were part of a special celebration February 5 to mark the fifth anniversary of the opening of Memphis Grizzlies House, a short-term residence for the families of St. Jude.

St. Jude finds more than 100 gene variations linked with response to leukemia treatment

2009-02-03

Scan of thousands of inherited genetic changes reveal specific variations linked to treatment failure and the fate of chemotherapy drugs in the body for children with acute lymphoblastic leukemia.

Univision radiothon encourages listeners across the country to support St. Jude

2009-02-02

St. Jude Children’s Research Hospital has once again joined forces with Univision Radio, the leading Spanish-language radio group in the United States, in its annual radiothon to help St. Jude find cures and save children. The event will be broadcast to more than 15 markets around the country, including Los Angeles, California; Miami, Florida; Chicago, Illinois; New York, New York; and Puerto Rico.

St. Jude finds more than 100 gene variations linked with response to leukemia treatment (news release)

2009-01-27

Scan of thousands of inherited genetic changes reveal specific variations linked to treatment failure and the fate of chemotherapy drugs in the body for children with acute lymphoblastic leukemia

Study shows how defective DNA repair triggers two neurological diseases (news release)

2009-01-15

St. Jude scientists’ findings in ataxia telangiectasia-like disease and Nijmegen breakage syndrome offer insight into the links between brain disease and cancer vulnerability in people carrying the diseases.

Scientists uncover secrets of drug metabolizing enzymes

2009-01-15

St. Jude researchers have discovered a chain of biochemical events that compromise the liver’s capacity to adequately clear many prescription drugs from the bodies of fetuses, young children and patients with liver cancer and other hepatic disorders.

Gene abnormality found to predict childhood leukemia relapse

2009-01-09

Scientists have identified genetic mutations that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

Study finds more effective treatment for pneumonia following influenza (news release)

2009-01-08

Results of St. Jude study could shape new treatments for secondary pneumonia

Gene therapy corrects sickle cell disease in laboratory study

2009-01-08

Using a harmless virus to insert a corrective gene into mouse blood cells, scientists at St. Jude have alleviated sickle cell disease pathology. In their studies, the researchers found that the treated mice showed essentially no difference from normal mice.

New insight into the cell’s busy chaperones

2009-01-08

When newly created proteins emerge from the cell’s protein-making machinery, they appear as useless, spaghetti-like strands. Only after these strands fold into their intricate, final globular shapes can proteins begin their work as enzymes and other essential cellular components.

Gene abnormality found to predict childhood leukemia relapse (news release)

2009-01-07

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL). Although the researchers caution that further research is needed to determine how changes in the gene, called IKZF1 or IKAROS, lead to leukemia relapse, the findings are likely to provide the basis for future diagnostic tests to assess the risk of treatment failure.

Support the Lady of America Fitness Centers Ab Crunch Challenge

2008-02-28

Put some heart in your New Year’s fitness resolution by joining the national Ab Crunch Challenge, a fitness challenge that will benefit your waistline and is expected to raise $1 million for St. Jude Children’s Research Hospital.

Medicine & Science News

2007-05-24

Medicine & Science News

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