Xinwei Cao, PhD

Assistant Member, St. Jude Faculty

Departments

Developmental Neurobiology

Contact Information

Xinwei Cao, PhD
Developmental Neurobiology
MS 323, Room D2025G
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Email: xinwei.cao@stjude.org
Phone: (901) 595-6525
FAX: (901) 595-3143

Education

PhD – University of Texas Southwestern Medical Center at Dallas, Texas
BS – Beijing (Peking) University, Beijing, China

Research Interests

• To define mechanisms that regulate the growth of the vertebrate nervous system
• To understand how growth-control mechanisms are coupled with patterning mechanisms to achieve the proper size, shape, and cytoarchitecture of the nervous system
• To determine the connection between growth-control mechanisms and human neurological tumors and malformations
• To identify the genetic basis of brain size evolution

Selected Publications

Denli AM, Cao X, Gage FH. miR-9 and TLX: chasing tails in neural stem cells. Nat Struct Mol Biol 16:346-347, 2009.

Cao X, Pfaff SL, Gage FH. YAP regulates neural progenitor cell number via the TEA domain transcription factor. Genes & Dev 22:3320-3334, 2008.

Cao X, Pfaff SL, Gage FH. A functional study of miR-124 in the developing neural tube. Genes & Dev 21:531-536, 2007.

Cao X, Yeo G, Muotri AR, Kuwabara T, Gage FH. Noncoding RNAs in the mammalian central nervous system. Annu Rev Neurosci 29:77-103, 2006.

Cao X, Südhof TC. Dissection of amyloid-β precursor protein-dependent transcriptional transactivation. J Biol Chem 279:24601-11, 2004.

Biederer T, Cao X, Südhof TC, Liu X. Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms. J Neurosci 22:7340-51, 2002.

Cao X, Südhof TC. A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293:115-20, 2001.

Last update: March 2012