XPD12-013 (IROPAST): Immune Constitution in Oncology Patients Following Autologous Stem Cell Transplant
Type of Protocol/Clinical Study
Associated Stem Cell Transplant Studies : Immune system reconstitution
This study is being done to learn more about how and when the immune system recovers after an autologous stem cell transplant. This study will also help us determine if the stem cell transplant itself helps the immune system to better recognize and fight off cancer cells. We also hope to learn more about effect of the high dose chemotherapy on the immune system.
- Estimate the time to full recovery of the immune system after an autologous stem cell transplant
- Learn if and how factors like gender, age, type of cancer, disease burden and conditioning regimen can affect the recovery of the immune system
- Learn if the autologous stem cell transplant affects certain types of immune cells ( NK cells) positively and can increase their activity against the cancer cells.
- Learn details about recovery of the immune system after chemotherapy.
- Research participants ages > 0 to 21 years inclusive with diagnosis of a solid tumor, brain tumor or lymphoma
- Enrolled on a therapeutic protocol or treatment plan that includes autologous stem cell transplant
- Parent/guardian willing to sign consent
- Patients receiving an autologous transplant for a disease other than solid tumor, brain tumor or lymphoma
Susanne Wendt, MD
The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.