David Shook, MD

David R. Shook, MD

Assistant Member, St. Jude Faculty


Bone Marrow Transplantation & Cellular Therapy

Contact Information

David Shook, MD
Bone Marrow Transplantation & Cellular Therapy
MS 1130, Room I-3307
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Email: david.shook@stjude.org
Phone: (901) 595-2369
FAX: (901) 595-7944


BS - Purdue University, West Lafayette, Indiana
MD - Johns Hopkins University School of Medicine, Baltimore, Maryland

Research Interests

Selected Publications

Imamura M, Shook D, Kamiya T, Shimasaki N, Chai SM, Coustan-Smith E, Imai C, Campana D. Autonomous growth and increased cytotoxicity of natural killer cells expressing membrane-bound interleukin-15. Blood July 8, 2014.

Srinivasan A, Panetta JC, Cross SJ, Pillai A, Triplett BM, Shook DR, Dallas MH, Hartford C, Sunkara A, Kang G, Jacobsen J, Choi J, Leung W. Phase I study of the safety and pharmacokinetics of plerixafor in children undergoing a second allogeneic hematopoietic stem cell transplantation for relapsed or refractory leukemia. Biol Blood Marrow Transplant 20(8):1224-8, 2014.

Srinivasan A, McLaughlin L, Wang C, Srivastava DK, Shook DR, Leung W, Hayden RT. Early infections after autologous hematopoietic stem cell transplantation in children and adolescents: the St. Jude experience. Transpl Infect Dis 16(1):90-7, 2014.

Rujkijyanont P, Morris C, Kang G, Gan K, Hartford C, Triplett B, Dallas M, Srinivasan A, Shook D, Pillai A, Pui CH, Leung W. Risk-adapted donor lymphocyte infusion based on chimerism and donor source in pediatric leukemia. Blood Cancer J 3:e137, 2013.

Dallas MH, Triplett B, Shook DR, Hartford C, Srinivasan A, Laver J, Ware R, Leung W. Long-term outcome and evaluation of organ function in pediatric patients undergoing haploidentical and matched related hematopoietic cell transplantation for sickle cell disease. Biol Blood Marrow Transplant 19(5):820-30, 2013.

Shook DR, Leung W. Natural killer cell therapy for cancer: delivering on a promise. Transfusion 53(2):245-8, 2013.

Shook DR, Triplett BM, Srinivasan A, Hartford C, Dallas MH, Pillai A, Laver J, Leung W. Successful allogeneic hematopoietic cell engraftment following a minimal conditioning regimen in children with relapsed or refractory solid tumors. Biol Blood Marrow Transplant October 9, 2012.

Inaba H, Yang J, Kaste SC, Hartford CM, Motosue MS, Chemaitilly W, Triplett BM, Shook DR, Pui CH, Leung W. Longitudinal changes in body mass and composition in survivors of childhood hematologic malignancies after allogeneic hematopoietic stem-cell transplantation. J Clin Oncol October 1, 2012.

Triplett BM, Wang C, Yang J, Dallas M, Hartford C, Howard V, Pillai A, Shook D, Srinivasan A, Laver J, Leung W. Effects of conditioning regimens and T-cell depletion in hematopoietic cell transplantation for primary immune deficiency. Biol Blood Marrow Transplant July 26, 2012.

Leung W, Pui CH, Coustan-Smith E, Yang J, Pei D, Gan K, Srinivasan A, Hartford C, Triplett BM, Dallas M, Pillai A, Shook D, Rubnitz JE, Sandlund JT, Jeha S, Inaba H, Ribeiro RC, Handgretinger R, Laver JH, Campana D. Detectable minimal residual disease before hematopoietic cell transplantation is prognostic but does not preclude cure for children with very-high-risk leukemia. Blood April 19, 2012.

Shook DR, Campana D. Natural killer cell engineering for cellular therapy of cancer. Tissue Antigens 78(6):409-415, 2011.

Cho D*, Shook DR*, Shimasaki N, Chang YS, Fujisaki H, Campana D. Natural killer cell activity against pediatric solid tumors. Clin Cancer Res 16(15):3901-3909, 2010.

Shook D, Coustan-Smith E, Ribeiro RC, Rubnitz JE, Campana D. Minimal residual disease quantitation in acute myeloid leukemia. Clinical Lymphoma, Myeloma & Leukemia 9(Suppl 3):S281-285, 2009.

Bristow RE, Gossett DR, Shook DR, Zahurak ML, Tomacruz RS, Armstrong DK, Montz FJ. Recurrent micropapillary serous ovarian carcinoma: The role of secondary cytoreductive surgery. Cancer 95(4):792-800, 2002.

Bristow RE, Gossett DR, Shook DR, Zahurak ML, Tomacruz RS, Armstrong DK, Montz FJ. Micropapillary serous ovarian carcinoma: surgical management and clinical outcome. Gynecol Oncol 86(2):163-170, 2002.

Last update: July 2014