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(St. Jude Reference #)
|Anaplastic Lymphoma Kinase (ALK) (SJ-93-0002)|
|Description||ALK is a kinase associated with several different types of cancer and can be used as a drug screening target. ALK inhibitors are contemplated to be useful as anti-cancer therapeutics. ALK antibodies are also provided.|
|Related Reagents||ALK antibody|
|Keywords||ALK, kinase, lymphoma, cancer, vaccine|
|Granted Patents or Published Applications||U.S. Patent Nos. 5,529,925; 5,770,421; 6,174,674; 6,451,997; 6,696,548; Australian Patent No. 679,833; European Patent No. 731,806|
|Related Scientific References||Morris, S.W. et al., “Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in Non-Hodgkin’s Lymphoma”, Science 263: 1281-1284 (1994);
Li, R and Morris, SW, "Development of Anaplastic Lymphoma Kinase (ALK) small molecule inhibitors for cancer therapy", Medicinal Research Reviews 28(3):372-412 (2008).
|Licensing Opportunities||We are currently seeking nonexclusive licensing opportunities in all fields for the development of this technology. Certain aspects of this technology are co-owned.|
Contact the Office of Technology Licensing (Phone: 901-595-2342, Fax: 901-595-3148) for more information.
Last update: September 2008