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Finding Cures. Saving Children.
Are there different types of sickle cell disease?
Yes, there are many different types of sickle cell disease, but Hemoglobin SS, Hemoglobin SC, and Sickle Beta Thalassemia are the most common types of sickle cell disease.
- Hemoglobin SS is homozygous sickle cell disease. The hemoglobin S gene is inherited from both parents.
- Hemoglobin SC is heterozygous sickle cell disease. Hemoglobin S is inherited from one parent and hemoglobin C is inherited from the other parent.
- Sickle Beta Thalassemia is heterozygous sickle cell disease. Hemoglobin S is inherited from one parent and the beta thalassemia gene is inherited from the other parent.
Related Facts:
- The sickle cell gene is caused by a mutation in the hemoglobin gene.
- Hemoglobin is the part of the red blood cell that carries oxygen.
- Normal hemoglobin is hemoglobin A.
- Sickle hemoglobin is hemoglobin S.
- Hemoglobin S is an abnormal type of hemoglobin.
- Most people with sickle cell disease do not have normal hemoglobin.
