Rehg: Pathologic expression of genes in genetically engineered mice

Genetically engineered mice, often known as transgenic or knockout mice, are now a standard means of exploring the complex molecular biologic effects of a gene. A pathologic assessment of genetically engineered mice is often crucial for the characterization of a gene’s function at the whole-animal level.

Pathogenesis of infectious diseases resulting from bacteria, protozoa, and viruses

Animal models of infectious diseases are often crucial for elucidation of the pathogenetic mechanism of virulence and the effect of vaccines as therapeutic modalities.


Last update: April 2003