Macromolecular & Small Molecule X-ray Diffraction


X-ray diffraction laboratory

X-ray Diffraction Equipment

The single-crystal X-ray diffraction laboratory is currently equipped with two FR591 rotating-anode generators, two DIP 2030 image-plate detectors (for the characterization of macromolecular structures) and a MACH3 kappa-axis goniometer (for small-molecule crystallography). The fully automated DIPs and MACH3 are controlled by Silicon Graphics O2 computers. Each diffractometer has dedicated Oxford Cryosystems Cryostream units that are capable of maintaining stable sample temperature as low as 100°K.

Structure solution, refinement, and visualization are performed on a local cluster of Silicon Graphics computers, with as-needed access to a four-processor DEC alpha computer located in the Hartwell Center.