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    Schulman: News Releases & Feature Stories

     
    06/19/2014
    Attaching an “on” switch for protein regulation

    Just as accessories like boots and gloves help humans adapt to their environment, St. Jude Children’s Research Hospital scientists have discovered a mechanism that serves as an “on” switch for the machinery that helps proteins accessorize.

     
     
    06/19/2014
    Mechanism discovered for attaching an “on” switch that helps cells accessorize proteins

    St. Jude Children’s Research Hospital scientists advance understanding of how cells manage their vast array of proteins and how system failures can lead to cancer and other diseases. (Brenda Schulman, PhD)

     
     
    05/01/2014
    St. Jude Children’s Research Hospital scientist elected to National Academy of Sciences

    Brenda Schulman, Ph.D., of St. Jude Children’s Research Hospital, has been elected to the National Academy of Sciences (NAS). Membership in the academy is a widely accepted mark of excellence in science and is considered one of the highest honors a scientist can receive.

     
     
    08/10/2012
    New regulatory mechanism discovered in cell system for eliminating unneeded proteins

    Work led by St. Jude Children’s Research Hospital scientists offers clues into molecular malfunction at the heart of a rare blood vessel disorder, revealing an important new regulator of cellular proteins. (Brenda Schulman, PhD)

     
     
    04/17/2012
    Brenda Schulman, Ph.D., recognized as 2012 fellow of the American Academy of Arts and Sciences

    Brenda Schulman, Ph.D., of St. Jude Children’s Research Hospital, has been named to the 2012 class of new Fellows and Foreign Honorary Members of the American Academy of Arts and Sciences (AAAS). Schulman was elected for her lab’s work on understanding a major form of cellular regulation, namely how ubiquitin-like proteins are conjugated to their target.

     
     
    11/04/2011
    Molecule serves as a key in some protein interactions

    St. Jude Children’s Research Hospital scientists discover that a post-production addition to most proteins can serve as a key to mediate protein interactions, which are at the foundation of life.

     
     
    05/24/2011
    Structural biologist Brenda Schulman, Ph.D., honored by international scientific group for work in protein science

    St. Jude Children’s Research Hospital scientist recognized with the Dorothy Crowfoot Hodgkin Award from The Protein Society

     
     
    10/05/2009
    Quest to understand APC identifies small protein’s key stabilizing role

    Four years after Brenda Schulman, PhD, Structural Biology and Genetics and Tumor Cell Biology, set out to explore the universe within the APC, her team recently sent back its first dispatch from the frontier.

     
     
    10/06/2008
    Study gives new insights into how cells accessorize their proteins

    St. Jude investigators have gained new insight into how the cell’s vast array of proteins would instantly be reduced to a confusion of lethally malfunctioning molecules without a system for proteins to “accessorize” in order to regulate their function. Just as eyeglasses improve vision, a coat provides warmth or an umbrella wards off rain, cells use a set of proteins called ubiquitin-like proteins (UBLs) as accessories that adapt their function as needed in the cell.

     
     
    02/20/2007
    Chemical switch triggers critical cell activities

    The freeze-frame image of a molecular relay race--in which one enzyme passes off a protein like a baton to another enzyme--illustrates how cells control some vital functions, according to a team of St. Jude investigators.

     
     
    10/24/2005
    Brenda Schulman: On Top of Her Game

    Each cell in the body is a playing field for a game much like "Capture the Flag." One researcher is on her way to a victory.

     
     
    06/16/2005
    Schulman receives elite honor from President Bush

    Brenda Schulman, PhD, has joined an elite group of the country's most promising early-career scientists and engineers.

     
     
    03/25/2005
    Schulman named Howard Hughes Investigator

    Brenda Schulman, PhD, of Structural Biology and Genetics and Tumor Cell Biology, has been selected to be a Howard Hughes Medical Institute (HHMI) investigator...

     
     
    11/05/2004
    Ubc12 protein points to anticancer drug targets

    A unique tail at one end of a protein called Ubc12 stabilizes a molecular workshop that assembles a switch that cells can use to accelerate cell replication.

     
     
    03/26/2003
    St. Jude researchers decipher multi-functional enzyme

    Scientists at St. Jude Children's Research Hospital have discovered how a single enzyme called E1 performs a rapid-fire, three-part chemical makeover of a protein that helps control some of the most fundamental biochemical processes of the human cell.