Currently we test and support the following browsers:
Please note that this is not intended to be an exhaustive list of browsers that support web standards, nor a test of browser compliance, nor a side-by-side comparison of various manufacturers’ browsers.
(St. Jude Reference #)
|Oligonucleotide Array for Monitoring T Cell Receptor Diversity (SJ-04-0031)|
|Description||An oligonucleotide microarray to monitor T cell reconstitution after hematopoietic stem cell transplantation is provided. T cell receptor (TCR) repertoire CDR3 spectratyping is currently used to distinguish various T cell populations. It involves amplification of each of the V-region families in a separate reaction that is analyzed sequentially on a sequencing gel. However, spectratyping requires numerous PCR reactions and only provides a qualitative analysis. This TCRβ repertoire-based oligonucleotide microarray provides a simple, rapid high-throughput tool to quantitatively and qualitatively analyze many TCR genes for use in clinical and research applications.|
|Keywords||T cell reconstitution, T cell diversity, Stem cell transplant|
|Granted Patents or Published Applications||US Publication No. 2010/0035764A1|
|Related Scientific References||Chen X, et al. A novel approach for the analysis of T-cell reconstitution by using a T-cell receptor beta-based oligonucleotide microarray in hematopoietic stem cell transplantation. Experimental Hematology 35 (2007) 831-841.|
|Licensing Opportunities||We are currently seeking licensing opportunities in all fields for the development of this technology.|
Contact the Office of Technology Licensing (Phone: 901-595-2342, Fax: 901-595-3148) for more information.
Last update: September 2010