Matthew W. Wilson, MD

Matthew W. Wilson, MD

Ophthalmology Division, Surgery Department
St. Jude Chair in Pediatric Ophthalmology
Full Professor, Department of Ophthalmology, University of Tennessee, Memphis


Education

MD - Emory University, Atlanta, GA (Medicine)
Internship - Emory University, Atlanta, GA(Transitional)
Residency - Emory University, Atlanta, GA (Ophthalmology)
Fellowship - Emory University, Atlanta, GA (Ophthalmic Path.)
Fellowship - Moorfields Eye Hospital, London, United Kingdom (Ocular Oncology)
Fellowship - Casey Eye Institute/Oregon Health Sciences University (Oculoplastics)


Selected Publications

Brinkman TM, Merchant TE, Li Z, Brennan R, Wilson M, Hoehn ME, Qaddoumi I, Phipps S, Srivastava D, Robison LL, Hudson MM, Krull KR. Cognitive function and social attainment in adult survivors of retinoblastoma: A report from the St. Jude Lifetime Cohort Study. Cancer 2014 Nov 24. [Epub ahead of print] PMID: 25421884 

Tse BC, Kaste SC, Brennan R, Orr B, Wilson MW. Enophthalmos and Choroidal Atrophy after Intraophthalmic Artery Chemotherapy for Retinoblastoma. Ophthalmology 2014 Oct 22.pii: S0161-6420(14)00880-X. doi: 10.1016/jophtha.2014.09.021. [Epub ahead of print] 

Pacak K, Chew EY, Pappo AS, Yang C, Lorenzo FR, Wilson MW, Aronow MB, Young JA, Popovic V, Zhuang Z. Ocular Manifestations of Hypoxia-Inducible Factor-2ɑ Paraganglioma-Somatostatinoma-Polycythemia Syndrome. Ophthalmology 2014 Aug 8. pii:S0161-6420(14)00532-6. doi:10.1016/j.ophtha.2014.06.019. PMID: 25109928. 

Willard VW, Qaddoumi I, Chen S, Zhang H, Brennan R. Rodriguez-Galindo C. Wilson MW, Phipps S. Developmental and Adaptive Functioning in Children with Retinoblastoma: A Longitudinal Investigation. J Clin Oncol 2014 Jun 14. Pii: JCO 2013.53. 1996. [Epub ahead of print]. PMID: 25024069. 

Toutounchian JJ, Steinle JJ, Makena PS, Waters CM, Wilson MW, Haik BG, Miller DD, Yates CR. Modulation of Radiation Injury Response in Retinal Endothelial Cells by Quinic Acid Derivative KZ-41 Involves p38 MAPK. PLoS One 2014 Jun23;9(6):e100210. doi:10.1371/journal.pone.0100210.eCollection 2014. PMID:24956278 

Sullivan EM, Wilson MW, Billups CA, Wu J, Merchant TE, Brennan RC, Haik BG, Shulkin B, Free TM, Given V, Rodriguez-Galindo C, Quaddoumi I. Pathologic Risk-based Adjuvant Chemotherapy for Unilateral Retinoblastoma Following Enucleation. J Pediatr Hematol Oncol 2014 Feb 26. PMID:24577551. 

McEvoy J, Nagahawatte P, Finkelstein D, Richards-Yutz J, Valentine M, Ma J, Mullighan C, Song G, Chen X, Wilson M, Brennan R, Pounds S, Becksfort J, Huether R, Lu C, Fulton RS, Fulton LL, Hong X, Dooling DJ, Ochoa K, Mardis ER, Wilson RK, Easton J, Zhang J, Downing JR, Ganguly A, Dyer MA: RB1 gene inactivation by chromothripsis in human retinoblastoma. Oncotarget Jan11;5(2) 438-450, 2014. PMID:24509483. 

Simpson ER, Gallie B, Laperrierre N, Beiki-Ardakani A, Kivelä T, Raivio V, Heikkonen J, Desjardins L, Dendale R, Mazal A, Bornfeld N, Sauerwein W, Flűehs D, Brualla L, Honavar SG, Reddy VAP, Suzuki S, Murakami N, Saakyan S, Valskiy V, Amiryan A, Seregard S, All-Eriksson C, Hjelmqvist L, Lundell G, Sinclair G, Lundell M, Damato B, Errington RD, Mayles P, Mayles H, Bergstrom C, Grossniklaus H, Crocker I, Butker E, Wilson M, Haik B, Geischen H, patra Pradeep, Duker J, Mignano J, Rivard M, Finger PT, (ABS-OOTF Chair), Semenova E, Choi W, Kalach NI: The American Brachytherapy Society consensus guidelines for plaque brachytherapy of uveal melanoma and retinoblastoma. Brachytherapy, An International Multidisciplinary Journal 2013 Dec. PII:S1538-4721(13)00396-6, doi:10.1016/j.brachy.2013.11.008 

Zhang Q, Jiang Y, Toutounchian J, Wilson MW, Morales-Tirado V, Miller DD, Yates CR, Steinle JJ. Novel Quinic Acid derivative KZ-41 prevents retinal endothelial cell apoptosis without inhibiting retinoblastoma cell death through p38 signaling. Invest Ophthalmol Vis Sci Sep 3;54(9)5937-43, 2013. doi: 10. 1167/iovs. 13-12326. PMID: 23942968 

Sansgiri RK, Wilson M, McCarville MB, Helton KJ. Imaging features of medulloepithelioma: report of four cases and review of the literature. Pediatr Radiol Oct 43(10):1344-56, 2013. doi: 10.1007/s00247-013-2718-x. Epub 2013. PMID: 23989751. 

Tse BC, Steinle JJ, Johnson D, Haik BG, Wilson MW. Superselective intraophthalmic Artery Chemotherapy in a nonhuman primate model: Histopathologic Findings. JAMA 2013 Apr 25:1-8. doi: 10.1001/jamaophthalmol.2013.2065. PMID:23619956 

Huddleston S, McNall-Knapp RY, Siatkowski M, Odom C, Brennan R, Wilson MW. A novel translocation t(11;13) (q21;q14.2) in a child with suprasellar primitive neuroectodermal tumor and retinoblastoma. Ophthalmic Genet 2013 Mar-Jun;34(1-2):97-100. doi: 10.3109/13816810.2012.719058. PMID: 22924820 

Kirzhner M, Shildkrot Y, Haik BG, Qaddoumi I, Rodriguez-Galindo C, Wilson MW. Pediatric anophthalmic sockets and orbital implants: Outcomes with Polymer-Coated-Implants. Ophthalmology 2013 Feb 8. doi:pii:S0161-6420(12)01101-3. 10.1016/j.ophtha.2012.11.022. PMID:23399376 

Hoehn ME, Kelly SR, Wilson MW, Walton RC, Cyclosporine 0.05% ophthalmic emulsion for the treatment of radiation-associated dry eye in children. Pediatr Blood Cancer 2013 Jan 17. doi: 10.1002/pbc.24461. PMID: 23335290 

Ditta LC, Choudhri AF, Tse BC, Landers MM, Haik BG, Steinle JJ, Williams JS, Wilson MW. Validating a non-human primate model of super-selective intraophthalmic artery chemotherapy: Comparing ophthalmic artery diameters. Invest Ophthalmol Vis Sci 2012 Nov 27;53(12):7791-4. doi: 10.1167/iovs.12-10605. PMID: 23111611 

Bhagat S, Bass J. Qaddoumi I, Brennan R, Wilson MW, Wu J, Galindo CR. Paglialonga A, Tognola G. Time-frequency analysis of transient-evoked otoacoustic emissions in children exposed to carboplatin chemotherapy. Audiol Neuro-otol 2012 Nov, 19(2):71-82. doi: 10. 1159/000343909. PMID: 23147804 

Qaddoumi I, Billups CA, Tagen M, Stewart CF, Wu J, Helton K, Merchant TE, Brennan R, Free TM, Given V, Haik BG, Rodriguez-Galindo C, Wilson MW. Topotecan and vincristine combination is effective against advanced bilateral intraocular retinoblastoma and has manageable toxicity. Cancer 2012 Nov 15;118(22):5663-70. doi: 10. 1002/cncr.27563. PMID: 22516936 

Ditta LC, Qayyum S, O’Brien TF, Choudhri AF, Wilson MW. Chondromyxoid Fibroma of the Orbit. Ophthal Plast Reconstr Surg 2012 Sep-Oct;28(5):e105-6. doi: 10.1097/IOP .0b013e31823bd1e0. PMID: 22743695 

Steinle JJ, Zhang Q, Thompson KE, Toutounchian J, Yates CR, Soderland C, Wang F, Stewart C, Haik BG, Williams JS, Mandrell TD, Johnson, DA, Wilson MW. Intra- ophthalmic artery chemotherapy triggers vascular toxicity through endothelial cell inflammation and leukostasis. Invest Ophthalmol Vis Sci 2012 Apr 30;53(4):2439-45. doi: 10. 1167/iovs.12-9466. PMID: 22427570 

Brennan RC, Wilson MW, Kaste S, Helton KJ, McCarville MB. US and MRI of pediatric ocular masses with histopathological correlation. Pediatr Radiol 2012 Jun;42(6):738-49. doi: 10.1007/s00247-012-2374-6. PMID: 22466750 

Qaddoumi I, Bass JK, Wu J, Billups CA, Wozniak AW, Merchant TE, Haik BG. Wilson MW, Rodriguez-Galindo C. Carboplatin-associated ototoxicity in children with retinoblastoma. J Clin Oncol 2012 Apr 1;30(10):1034-41. doi: 10.1200/JCO.2011.36.9744. PMID: 22370329 

Zhang J, Benavente CA McEvoy J, Flores-Otero J, Ding L, Chen X, Ulyanov A, Wu G, Wilson M, Wang J, Brennan R, Rusch M, Manning AL, Ma J, Easton J, Shurtleff S, Mullighan C, Pounds S, Mukatira S, Gupta P, Neale G, Zhao D, Lu C, Fulton RS, Fulton LL, Hong X, Dooling DJ, Ochoa K, Naeve C, Dyson NJ, Mardis ER, Bahrami A, Ellison D, Wilson RK, Downing JR, Dyer MA. A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature 2012 Jan 11;481(7381):329-34 doi: 10.1038/nature10733. PMID: 22237022 

Jaradat I, Yousef YA, Mehyar M, Sultan I, Khurma S, Al-Rawashded K, Wilson M, Qaddoumi I, Salem A, Alnawaiseh I. Retinoblastoma in Jordan: an epidemiological study (2006-2010). Hematol Oncol Stem Cell Ther 2011 Third Quarter;4(3);126-31. PMID: 21982886 

Shildkrot Y, Kirzhner M, Haik BG, Qaddoumi I, Rodriguez-Galindo C, Wilson MW. The effect of cancer therapies on pediatric anophthalmic sockets. Ophthalmology 2011 Dec:118(12):2480-6. doi: 10.1016/j.ophtha.2011.05.024. PMID: 21856015 

Wilson MW, Haik BG, Dyer MA. Superselective intraophthalmic artery chemotherapy: What we do not know. Arch Ophthalmol 2011 Nov;129(11):1490-1. doi: 10.1001/archophthalmol.2011.361. PMID: 22084220 

Wilson MW, Jackson JS, Phillips BX, Buchanan J, Frase S, Wang F, Steinle JJ, Stewart CF, Mandrell TD, Haik BG, Williams JS. Real-time ophthalmoscopic findings of superselective intraophthalmic artery chemotherapy in a nonhuman primate model. Arch Ophthalmol 2011 Nov;129(11):1458-65. doi: 10. 1001/archophthalmol.2011.330. PMID: 22084215 

Ditta LC, Shildkrot Y, Wilson MW. Outcomes in 15 patients with conjunctival melanoma treated with adjuvant topical Mitomycin C: Complications and recurrences. Ophthalmol 2011 Sep;118(9):1754-59. doi: 10. 1016/j.ophtha.2011.01.060. PMID: 21652078 

McEvoy J, Flores-Otero J, Zhang J, Nemeth K, Brennan R, Bradley C, Krafcik F, Rodriguez-Galindo C, Wilson M, Xiong S, Lozano G, Sage J, Fu L, Louhibi L, Trimarchi J, Pani A, Smeyne R, Johnson D, Dyer MA. Coexpression of normally incompatible developmental pathways in retinoblastoma genesis. Cancer Cell 2011 Aug 16;20(2):260-75. doi: 10. 1016/j.ccr.2011.07.005. PMID: 21840489 

Shildkrot Y, Thomas F, Al-Hariri A, Fry CL, Haik BG, Wilson MW. Socioeconomic Factors and diagnosis of uveal melanoma in the Mid-Southern United States. Curr Eye Res 2011 Sep;36(9):824-30. doi: 10.3109/02713683.2011.593109. PMID: 21762015 

Brennan R, Federico S, Bradley C, Zhang J, Flores-Otero J, Wilson MW, Stewart C. Zhu F, Guy K, Dyer MA. Targeting the p53 pathway in retinoblastoma with subconjunctival Nutlin-3a. Cancer Res 2011 Jun 15;71(12):4205-13. doi: 10. 1158/0008-5472.CAN-11-0058. PMID: 21515735