Cancer Center Members

Doralina Anghelescu, MD

Department of Anesthesiology
Research interests: pain management, anesthesia risks, palliative care

Gregory T. Armstrong, MD, MSCE

Department of Epidemiology & Cancer Control
Research interests: pediatric neuro-oncology and cancer survivorship

Richard A. Ashmun, PhD

Department of Tumor Cell Biology
Research interests: applications of flow cytometry and cell separation

Armita Bahrami, MD

Department of Pathology
Research interests: Pediatric bone and soft tissue tumors

Sharyn D. Baker, PharmD, PhD

Department of Pharmaceutical Sciences
Research interests: clinical pharmacology of tyrosine kinase inhibitors

Suzanne J. Baker, PhD

Department of Developmental Neurobiology
Research interests: PTEN and key signaling pathways in brain tumors

Don Bashford, PhD

Department of Structural Biology
Research interests: Computational molecular biophysics

Hartmut Berns, PhD

Director, Transgenic/Gene Knockout Shared Resource

Deepa Bhojwani, MD

Department of Oncology
Research interests: improving therapy for childhood leukemia/lymphoma

Mark Bix, PhD

Department of Immunology
Research interests: cytokine gene regulation in T-cell differentiation

Frederick A. Boop, MD

Department of Surgery
Research interests: brain tumor clinical trials; functional neuro-imaging in children; advanced surgical techniques in children

James M. Boyett, PhD

Department of Biostatistics
Research interests: statistical design and analysis of clinical trials

Rachel C. Brennan, MD

Department of Oncology
Research interests: retinoblastoma therapy and late effects; translating preclinical research into clinical trials; Phase I clinical trials; complications of chemotherapy

Tara M. Brinkman, PhD

Department of Epidemiology & Cancer Control
Research interests: Psychosocial outcomes of childhood cancer

Alberto Broniscer, MD

Department of Oncology
Research interests: biology and treatment of high-grade gliomas

Wassim Chemaitilly, MD

Department of Pediatric Medicine
Research interests: late effects observed in childhood cancer survivors

Taosheng Chen, PhD, PMP®

Department of Chemical Biology & Therapeutics
Research interests: small-molecule transcription factor drug discovery

Cheng Cheng, PhD

Department of Biostatistics
Research interests: statistical methods in cancer genomics and genetics

P. Joan Chesney, MD

Clinical Education & Training Office

Hongbo Chi, PhD

Department of Immunology
Research interests: cellular signaling in innate and adaptive immunity

John K. Choi, MD, PhD

Department of Pathology
Research interest: To understand the mechanisms by which the transcription factor E2A regulate normal and leukemic precursor B cell proliferations

Robert R. Clark, MS, FACHE

Administration, Government Relations

Wilson K. Clements, PhD

Department of Hematology
Research interests: vascular/hematopoietic development and leukemia

Heather Conklin, PhD

Department of Psychology
Research interests: cognitive outcomes of childhood cancer treatment

Cheryl Cox, PhD

Department of Epidemiology & Cancer Control
Research interests: health promotion, early/late effects of treatment

Alessandra d'Azzo, PhD

Department of Genetics
Research interests: intracellular degradation in development and disease

Mari H. Dallas, MD

Department of Bone Marrow Transplantation & Cellular Therapy
Stem cell and T-cell development; Cord blood transplant; Infections and immune reconstitution after bone marrow transplant

Andrew M. Davidoff, MD

Department of Surgery
Research interests: angiogenesis inhibition for cancer therapy

James R. Downing, MD

St. Jude President and Chief Executive Officer, Department of Pathology
Research interests: the molecular pathology of acute leukemia

Michael A. Dyer, PhD

Department of Developmental Neurobiology
Research interests: retinal development and retinoblastoma

David W. Ellison, MD, PhD

Department of Pathology
Research interests: pathologic/molecular classification of CNS tumors

Eric J. Enemark, PhD

Department of Structural Biology
Research interests: Molecular mechanisms of DNA replication

William E. Evans, PharmD

Department of Pharmaceutical Sciences
Research interests: pharmacogenomics of antileukemic agents in children

Sara M. Federico, MD

Department of Oncology
Research interests: biology and clinical investigation of pediatric soft tissue sarcomas; translational research and novel drug development for pediatric solid malignancies

Sharon Frase

Cell & Tissue Imaging Center

Kevin W. Freeman, PhD

Department of Oncology
Research interest: genetic interactions that give rise to neuroblastoma; preclinical models of neuroblastoma

Victoria Centonze Frohlich, PhD

Cell & Tissue Imaging Center

Naoaki Fujii, PhD

Department of Chemical Biology & Therapeutics
Research interests: medicinal chemistry, chemical biology, PDZ domain

Wayne L. Furman, MD

Department of Oncology
Research interests: new drug development, neuroblastoma, liver tumors

Amar Gajjar, MD

Department of Oncology
Research interests: novel treatments for children with brain tumors

Richard J. Gilbertson, MD, PhD

Department of Developmental Neurobiology
Research interests: the cellular and molecular origins of brain tumors

Daniel M. Green, MD

Department of Epidemiology and Cancer Control
Research interests: Late effects of treatment for childhood cancer, particularly fertility and pregnancy outcome, and late effects of treatment for Wilms tumor.

Douglas R. Green, PhD

Department of Immunology
Research interests: apoptosis, autophage and mitochondria

Suzanne A. Gronemeyer, PhD

Academic Programs

Gerard Grosveld, PhD

Department of Genetics
Research interests: the role of chromosome translocations in cancer

Tanja A. Gruber, MD, PhD

Department of Oncology
Research interests: molecular pathology of infantile leukemia

R. Kiplin Guy, PhD

Department of Chemical Biology & Therapeutics
Research interests: chemical biology and orphan disease drug discovery

Young-Goo Han, PhD

Department of Developmental Neurobiology
Research interests: Primary cilia in brain development and tumorigenesis

Julie H. Harreld, MD

Department of Radiological Sciences
Research interests: Development of novel MR contrast mechanisms and their application to the study of pediatric brain tumors and CNS treatment sequelae

Mark E. Hatley, MD, PhD

Department of Oncology
Research interests: Cellular and molecular origins of rhabdomyosarcoma

Kathleen J. Helton, MD

Department of Radiological Sciences
Research interests: cerebral perfusion and white matter connectivity

Linda M. Hendershot, PhD

Department of Tumor Cell Biology
Research interests: ER quality control in development and disease

Melissa M. Hudson, MD

Department of Oncology
Research interests: health outcomes after childhood cancer

Hiroto Inaba, MD, PhD

Department of Oncology
Research Interests: novel therapies for leukemia/lymphoma, especially acute myeloid leukemia and lymphoblastic lymphoma

Pamela James, BS, MS

Director, CPDMO

Sima Jeha, MD

Department of Oncology
Research interests: childhood leukemias, developmental therapeutics

Jesse J. Jenkins, III, MD

Department of Pathology
Research interests: childhood tumor diagnosis by molecular techniques

Thirumala-Devi Kanneganti, PhD

Department of Immunology
Research interests: mechanisms of host defense and inflammation

Sue C. Kaste, DO

Department of Radiological Sciences
Research interests: skeletal toxicities in childhood cancer survivors

Robert A. Kaufman, MD

Department of Radiological Sciences
Research interests: Dose reduction in CT studies in infants and children with cancer: strategies, risks and benefits

Robert C. Klesges, PhD

Department of Epidemiology and Cancer Control
Research interests: cancer prevention and control in adults & children

Paul Klimo Jr., MD

Department of Oncology
Research interests: vascular disorders and brain tumors

James L. Klosky, PhD

Department of Psychology
Research interests: men's and women's health in cancer survivorship

Matthew J. Krasin, MD

Department of Radiological Sciences
Research interests: developing local therapy strategies for sarcomas

Richard Kriwacki, PhD

Department of Structural Biology
Research interests: structural basis of tumor suppressor function

Kevin R. Krull, PhD

Department of Epidemiology and Cancer Control
Research interests: The neurocognitive outcomes and late effects of childhood cancer, as well as using biologic and psychosocial moderators/mediators of these effects to design interventions for deficits in attention, memory, and executive functions

Larry E. Kun, MD

Department of Radiological Sciences
Research interests: improving diagnosis and therapy of brain tumors

Mondira Kundu, MD, PhD

Department of Pathology
Research Interests: Mechanisms involved in mitochondrial clearance and links to hematopoietic malignancies

Myriam Labelle, PhD

Department of Developmental Neurobiology
Research interests: role of platelets in cancer metastasis

Richard E. Lee, PhD

Department of Oncology
Research interests: Development of new chemotherapeutic agents

Wing H. Leung, MD, PhD

Department of Bone Marrow Transplantation & Cellular Therapy
Research interests: NK cell and stem cell transplantation, late effects

Vasiliki Leventaki, MD

Department of Pathology
Research interests: mechanisms of pathogenesis in pediatric lymphomas

Belinda N. Mandrell, PhD, RN, PNP

Division of Nursing Research
Research interests: Mechanisms of cancer related symptoms

Mary E. (Beth) McCarville, MD

Department of Radiological Sciences
Research interests: solid tumor imaging and contrast-enhanced sonography

Shannon McKinney-Freeman, PhD

Department of Hematology
Research interests: directed differentiation of pluripotent stem cells and hematopoietic stem cell specification

Peter J. McKinnon, PhD

Department of Genetics
Research interests: DNA damage responses in the nervous system

Thomas E. Merchant, DO, PhD

Department of Radiological Sciences
Research interests: radiation-related CNS effects

Monika Metzger, MD

Department of Oncology
Research interests: Hodgkin and non-Hodgkin lymphomas, leukemias, IOP

Tanja Mittag, PhD

Department of Structural Biology
Research interest: structure/function relationship of dynamic and disordered protein complexes in signal transduction

Tudor Moldoveanu, PhD

Department of Chemical Biology & Therapeutics
Research interests: programmed cell death in health and disease

James I. Morgan, PhD

Department of Developmental Neurobiology
Research interests: control of neuronal death and differentiation

Charles G. Mullighan, MBBS(Hons), MSc, MD

Department of Pathology
Research interests: genomic profiling of acute leukemia

Daniel A. Mulrooney, MD, MS

Department of Oncology
Research interests: cardiovascular outcomes of cancer therapy

Peter J. Murray, PhD

Department of Infectious Diseases
Research interests: control of inflammatory responses

Clayton W. Naeve, PhD

Chief Information Officer, Information Sciences
Research interests: bioinformatics, high-throughput biotechnologies

Fariba Navid, MD

Department of Oncology
Research interests: treatment of pediatric sarcomas and melanoma

Geoffrey Neale, PhD

Hartwell Center for Bioinformatics & Biotechnology

Kirsten K. Ness, PT, PhD

Department of Epidemiology & Cancer Control
Research interests: functional limitations among cancer survivors

Arthur W. Nienhuis, MD

Department of Hematology
Research interests: genetic therapy of hematological diseases

Leta K. Nutt, PhD

Department of Pathology
Research interests: metabolic regulation of apoptosis; calcium homeostasis during apoptosis; metabolic regulation of ER stress

Stacey K. Ogden, PhD

Department of Cell & Molecular Biology
Research Interest: mechanisms of Hedgehog signal transduction in development and disease

Robert J. Ogg, PhD

Department of Radiological Sciences
Research interests: brain function of survivors of childhood diseases

Rohit P. Ojha, DrPH

Department of Epidemiology & Cancer Control
Research interests: Prediction of outcomes and late-effects among cancer survivors

Guillermo Oliver, PhD

Department of Genetics
Research interests: development of the CNS and lymphatic vasculature

Arzu Onar-Thomas, PhD

Department of Biostatistics
Research interests: Ph I-II designs, bioinformatics, survival analy

Joseph T. Opferman, PhD

Department of Cell & Molecular Biology
Research interests: regulation of cell death during hematopoiesis

Brent A. Orr, MD, PhD

Department of Pathology
Research interests: molecular classification of tumors of the nervous system

Alberto Pappo, MD

Department of Oncology
Research Interests: Development of novel therapies for pediatric solid tumors with special interest in: pediatric melanoma; soft tissue sarcomas; pediatric gastrointestinal stromal tumors

Janet F. Partridge, PhD

Department of Pathology
Research interests: chromosome segregation, heterochromatin assembly

Zoltán Patay, MD, PhD

Department of Radiological Sciences
Research interests: multimodality tumor tissue characterization by MRI

Junmin Peng, PhD

Department of Structural Biology
Research interests: Proteomics to ubiquitin biology and human disease

Sean Phipps, PhD

Department of Psychology
Research interests: coping and adjustment in children with cancer

Asha B. Pillai, MD

Department of Bone Marrow Transplantation & Cellular Therapy
Research interests: immunoregulatory cell networks; prevention of graft-versus-host disease (GVHD); immune mechanisms of separation of GVT from GVHD

Philip M. Potter, PhD

Department of Chemical Biology & Therapeutics
Research interests: anticancer drug hydrolysis by carboxylesterases

Stan Pounds, PhD

Department of Biostatistics
Research interests: develop statistical methods for genomics studies

Ching-Hon Pui, MD

Department of Oncology
Research interests: biology and treatment of childhood leukemia

Ibrahim Qaddoumi, MD, MS

Department of Oncology
Research interests: low grade gliomas as unique diseases; advancing study of pediatric brain tumors in developing countries through international collaboration, twinning, and telemedicine

Richard Rahija, DVM, PhD

Animal Resource Center

Bhaskar N. Rao, MD

Department of Surgery
Research interests: surgical management of sarcomas and rare tumors

Wilburn E. Reddick, PhD

Department of Radiological Sciences
Research interests: white matter injury and neurocognitive functioning

Mary V. Relling, PharmD

Department of Pharmaceutical Sciences
Research interests: pharmacokinetics and genetics of leukemia therapy

Raul C. Ribeiro, MD

Department of Oncology
Research interests: hematological malignancies

Giles W. Robinson, MD

Department of Oncology
Research interests: Origin and genomics of medulloblastoma, translational studies

Leslie L. Robison, PhD

Department of Epidemiology & Cancer Control
Research interests: pediatric cancer epidemiology and outcomes

Charles O. Rock, PhD

Department of Infectious Diseases
Research interests: membrane phospholipid metabolism

Martine F. Roussel, PhD

Department of Tumor Cell Biology
Research interests: genes and microRNAs in brain tumors

Jeffrey E. Rubnitz, MD, PhD

Department of Oncology
Research interests: treatment of acute myeloid leukemia

Noah D. Sabin, MD, JD

Department of Radiological Sciences
Research interests: the imaging of brain tumors and neuroimaging of  long-term survivors of childhood cancer

John T. Sandlund, MD

Department of Oncology
Research interests: clinical and biologic investigation of NHL and ALL

John A. Sandoval, MD

Department of Surgery
Research interests: Pediatric surgical oncology

Victor M. Santana, MD

Department of Oncology
Research interests: novel therapeutics, neuroblastoma, research ethics

Erin G. Schuetz, PhD

Department of Pharmaceutical Sciences
Research interests: mechanisms of human variation in drug response

John D. Schuetz, PhD

Department of Pharmaceutical Sciences
Research interests: regulation and function of ABC transporters

Brenda Schulman, PhD

Department of Structural Biology
Research interests: cellular regulation by ubiquitin-like proteins

Anang A. Shelat, PhD

Department of Chemical Biology & Therapeutics
Research interests: Multi-scale modeling of biological and chemical data

Charles J. Sherr, MD, PhD

Department of Tumor Cell Biology
Research interests: tumor suppressor-dependent signaling networks

David R. Shook, MD

Department of Bone Marrow Transplantation and Cellular Therapy
Research interests: Transplantation for solid tumors; cellular therapy

Barry L. Shulkin, MD

Department of Radiological Sciences
Research interests: PET CT imaging and evaluation of pediatric tumors

Ronald L. Smith, MHA

Vice President for Scientific Operations

Scott E. Snyder, PhD

Departments of Radiological Sciences and Chemical Biology & Therapeutics
Research interests: design of radioactive drugs for medical imaging

David J. Solecki, PhD

Department of Developmental Neurobiology
Research interests: cell polarity in neuron precursor differentiation

Brian P. Sorrentino, MD

Department of Hematology
Research interests: gene therapy and hematopoietic stem cell biology

Alex Sparreboom, PhD

Department of Pharmaceutical Sciences
Research interests: drug intake carriers in kidney and liver

Ashok Srinivasan, MD

Department of Bone Marrow Transplant & Cellular Therapy
Research interests: infections in the immune-compromised host

Deo Kumar Srivastava, PhD

Department of Biostatistics
Research interests: clinical trials, robust methods, survival analysis

Clinton F. Stewart, PharmD

Department of Pharmaceutical Sciences
Research interests: pharmacology of anticancer drugs in children

J. Paul Taylor, MD, PhD

Department of Cell & Molecular Biology
Research interests: To understand the roles of catabolic pathways

Michael R. Taylor, PhD

Department of Chemical Biology & Therapeutics
Research interests: using zebrafish to study the development, maintenance, and function of the blood-brain barrier; model pediatric brain tumors; perform high-throughput small molecule screens

Brandon Triplett, MD

Department of Bone Marrow Transplant & Cellular Therapy
Research interests: Hematopoietic cell transplant for high risk leukemia; Use of alternative donors in patients lacking a fully matched sibling donor; Immune reconstitution following hematopoietic cell transplant

Dana Wallace, MS

Administration, Comprehensive Cancer Center

Stephen White, DPhil

Department of Structural Biology
Research interests: structural analysis of catalysis and DNA repair

Matthew W. Wilson, MD

Department of Surgery
Research interests: surgical ophthalmology

Karen D. Wright, MD

Department of Oncology
Research interests: Ependymoma, atypical teratoid rhabdoid tumors, infant brain tumors

Jianrong (John) Wu, PhD

Department of Biostatistics
Research interests: design and analysis of preclinical and clinical trials

Jun J. Yang, PhD

Department of Pharmaceutical Sciences
Research interests: the genomics of hematologic tumors, with particular interests in genomic characterization of inter-patient variability in anti-leukemia drug response and disease susceptibility

Stanislav S. Zakharenko, MD, PhD

Department of Developmental Neurobiology
Research interests: synaptic and neuronal mechanisms of schizophrenia

Gerard P. Zambetti, PhD

Department of Biochemistry
Research interests: p53 function in tumor suppression and tumorigenesis

Jinghui Zhang, PhD

Department of Computational Biology
Research interest: computational methods for cancer genomics

Jie Zheng, PhD

Department of Structural Biology
Research interests: protein NMR and structure-based drug discovery

Liqin Zhu, PhD

Department of Developmental Neurobiology
Research interests: stem cells in normal and malignant development

Jian Zuo, PhD

Department of Developmental Neurobiology
Research interests: hair cell function and regeneration in mice