Doralina Anghelescu, MDDepartment of Anesthesiology
Research interests: pain management, anesthesia risks, palliative care
Gregory T. Armstrong, MD, MSCEDepartment of Epidemiology & Cancer Control
Research interests: pediatric neuro-oncology and cancer survivorship
Richard A. Ashmun, PhDDepartment of Tumor Cell Biology
Research interests: applications of flow cytometry and cell separation
Armita Bahrami, MDDepartment of Pathology
Research interests: Pediatric bone and soft tissue tumors
Sharyn D. Baker, PharmD, PhDDepartment of Pharmaceutical Sciences
Research interests: clinical pharmacology of tyrosine kinase inhibitors
Suzanne J. Baker, PhDDepartment of Developmental Neurobiology
Research interests: PTEN and key signaling pathways in brain tumors
Don Bashford, PhDDepartment of Structural Biology
Research interests: Computational molecular biophysics
Hartmut Berns, PhDDirector, Transgenic/Gene Knockout Shared Resource
Mark Bix, PhDDepartment of Immunology
Research interests: cytokine gene regulation in T-cell differentiation
Frederick A. Boop, MDDepartment of Surgery
Research interests: brain tumor clinical trials; functional neuro-imaging in children; advanced surgical techniques in children
James M. Boyett, PhDDepartment of Biostatistics
Research interests: statistical design and analysis of clinical trials
Rachel C. Brennan, MDDepartment of Oncology
Research interests: retinoblastoma therapy and late effects; translating preclinical research into clinical trials; Phase I clinical trials; complications of chemotherapy
Paul K. Brindle, PhDDepartment of Biochemistry
Research interests: gene regulation by transcriptional coactivators
Tara M. Brinkman, PhDDepartment of Epidemiology & Cancer Control
Research interests: Psychosocial outcomes of childhood cancer
Alberto Broniscer, MDDepartment of Oncology
Research interests: biology and treatment of high-grade gliomas
Wassim Chemaitilly, MDDepartment of Pediatric Medicine
Research interests: late effects observed in childhood cancer survivors
Taosheng Chen, PhD, PMP®Department of Chemical Biology & Therapeutics
Research interests: small-molecule transcription factor drug discovery
Cheng Cheng, PhDDepartment of Biostatistics
Research interests: statistical methods in cancer genomics and genetics
P. Joan Chesney, MDClinical Education & Training Office
John K. Choi, MD, PhDDepartment of Pathology
Research interest: To understand the mechanisms by which the transcription factor E2A regulate normal and leukemic precursor B cell proliferations
Robert R. Clark, MS, FACHEAdministration, Government Relations
Heather Conklin, PhDDepartment of Psychology
Research interests: cognitive outcomes of childhood cancer treatment
Cheryl Cox, PhDDepartment of Epidemiology & Cancer Control
Research interests: health promotion, early/late effects of treatment
Alessandra d'Azzo, PhDDepartment of Genetics
Research interests: intracellular degradation in development and disease
Mari H. Dallas, MDDepartment of Bone Marrow Transplantation & Cellular Therapy
Stem cell and T-cell development; Cord blood transplant; Infections and immune reconstitution after bone marrow transplant
Andrew M. Davidoff, MDDepartment of Surgery
Research interests: angiogenesis inhibition for cancer therapy
James R. Downing, MDSt. Jude Deputy Director, St. Jude Scientific Director, Department of Pathology
Research interests: the molecular pathology of acute leukemia
Michael A. Dyer, PhDDepartment of Developmental Neurobiology
Research interests: retinal development and retinoblastoma
David W. Ellison, MD, PhD, MRCP, FRCPCHDepartment of Pathology
Research interests: pathologic/molecular classification of CNS tumors
Eric J. Enemark, PhDDepartment of Structural Biology
Research interests: Molecular mechanisms of DNA replication
William E. Evans, PharmDSt. Jude Director, Department of Pharmaceutical Sciences
Research interests: pharmacogenomics of antileukemic agents in children
Sara M. Federico, MDDepartment of Oncology
Research interests: biology and clinical investigation of pediatric soft tissue sarcomas; translational research and novel drug development for pediatric solid malignancies
Sharon FraseCell & Tissue Imaging Center
Kevin W. Freeman, PhDDepartment of Oncology
Research interest: genetic interactions that give rise to neuroblastoma; preclinical models of neuroblastoma
Victoria Centonze Frohlich, PhDCell & Tissue Imaging Center
Naoaki Fujii, PhDDepartment of Chemical Biology & Therapeutics
Research interests: medicinal chemistry, chemical biology, PDZ domain
Wayne L. Furman, MDDepartment of Oncology
Research interests: new drug development, neuroblastoma, liver tumors
Amar Gajjar, MDDepartment of Oncology
Research interests: novel treatments for children with brain tumors
Richard J. Gilbertson, MD, PhDDepartment of Developmental Neurobiology
Research interests: the cellular and molecular origins of brain tumors
Daniel M. Green, MDDepartment of Epidemiology and Cancer Control
Research interests: Late effects of treatment for childhood cancer, particularly fertility and pregnancy outcome, and late effects of treatment for Wilms tumor.
Douglas R. Green, PhDDepartment of Immunology
Research interests: apoptosis, autophage and mitochondria
Suzanne A. Gronemeyer, PhDAcademic Programs
Gerard Grosveld, PhDDepartment of Genetics
Research interests: the role of chromosome translocations in cancer
Tanja A. Gruber, MD, PhDDepartment of Oncology
Research interests: molecular pathology of infantile leukemia
R. Kiplin Guy, PhDDepartment of Chemical Biology & Therapeutics
Research interests: chemical biology and orphan disease drug discovery
Young-Goo Han, PhDDepartment of Developmental Neurobiology
Research interests: Primary cilia in brain development and tumorigenesis
Julie H. Harreld, MDDepartment of Radiological Sciences
Research interests: Development of novel MR contrast mechanisms and their application to the study of pediatric brain tumors and CNS treatment sequelae
Mark E. Hatley, MD, PhDDepartment of Oncology
Research interests: Cellular and molecular origins of rhabdomyosarcoma
Kathleen J. Helton, MDDepartment of Radiological Sciences
Research interests: cerebral perfusion and white matter connectivity
Linda M. Hendershot, PhDDepartment of Tumor Cell Biology
Research interests: ER quality control in development and disease
Scott C. Howard, MD, MSDepartment of Oncology
Research interests: leukemia and lymphoma, international outreach
Melissa M. Hudson, MDDepartment of Oncology
Research interests: health outcomes after childhood cancer
James N. Ihle, PhDDepartment of Biochemistry
Research interests: cytokine binding, signaling and cellular responses
Hiroto Inaba, MD, PhDDepartment of Oncology
Research Interests: novel therapies for leukemia/lymphoma, especially acute myeloid leukemia and lymphoblastic lymphoma
Pamela James, BS, MSDirector, CPDMO
Sima Jeha, MDDepartment of Oncology
Research interests: childhood leukemias, developmental therapeutics
Jesse J. Jenkins, III, MDDepartment of Pathology
Research interests: childhood tumor diagnosis by molecular techniques
Thirumala-Devi Kanneganti, PhDDepartment of Immunology
Research interests: mechanisms of host defense and inflammation
Sue C. Kaste, DODepartment of Radiological Sciences
Research interests: skeletal toxicities in childhood cancer survivors
Robert A. Kaufman, MDDepartment of Radiological Sciences
Research interests: Dose reduction in CT studies in infants and children with cancer: strategies, risks and benefits
Robert C. Klesges, PhDDepartment of Epidemiology and Cancer Control
Research interests: cancer prevention and control in adults & children
Paul Klimo Jr., MDDepartment of Oncology
Research interests: vascular disorders and brain tumors
James L. Klosky, PhDDepartment of Psychology
Research interests: men's and women's health in cancer survivorship
Matthew J. Krasin, MDDepartment of Radiological Sciences
Research interests: developing local therapy strategies for sarcomas
Richard Kriwacki, PhDDepartment of Structural Biology
Research interests: structural basis of tumor suppressor function
Kevin R. Krull, PhDDepartment of Epidemiology and Cancer Control
Research interests: The neurocognitive outcomes and late effects of childhood cancer, as well as using biologic and psychosocial moderators/mediators of these effects to design interventions for deficits in attention, memory, and executive functions
Larry E. Kun, MDDepartment of Radiological Sciences
Research interests: improving diagnosis and therapy of brain tumors
Mondira Kundu, MD, PhDDepartment of Pathology
Research Interests: Mechanisms involved in mitochondrial clearance and links to hematopoietic malignancies
Joseph H. Laver, MDDepartment of Pediatric Medicine
Research interests: Pediatric stem cell transplantation and non-Hodgkin lymphoma
Richard E. Lee, PhDDepartment of Oncology
Research interests: Development of new chemotherapeutic agents
Wing H. Leung, MD, PhDDepartment of Bone Marrow Transplantation & Cellular Therapy
Research interests: NK cell and stem cell transplantation, late effects
Belinda N. Mandrell, PhD, RNDivision of Nursing Research
Research interests: Mechanisms of cancer related symptoms
Mary E. (Beth) McCarville, MDDepartment of Radiological Sciences
Research interests: solid tumor imaging and contrast-enhanced sonography
Shannon McKinney-Freeman, PhDDepartment of Hematology
Research interests: directed differentiation of pluripotent stem cells and hematopoietic stem cell specification
Peter J. McKinnon, PhDDepartment of Genetics
Research interests: DNA damage responses in the nervous system
Thomas E. Merchant, DO, PhDDepartment of Radiological Sciences
Research interests: radiation-related CNS effects
Monika Metzger, MDDepartment of Oncology
Research interests: Hodgkin and non-Hodgkin lymphomas, leukemias, IOP
Tanja Mittag, PhDDepartment of Structural Biology
Research interest: structure/function relationship of dynamic and disordered protein complexes in signal transduction
James I. Morgan, PhDDepartment of Developmental Neurobiology
Research interests: control of neuronal death and differentiation
Charles G. Mullighan, MBBS(Hons), MSc, MDDepartment of Pathology
Research interests: genomic profiling of acute leukemia
Daniel A. Mulrooney, MD, MSDepartment of Oncology
Research interests: cardiovascular outcomes of cancer therapy
Peter J. Murray, PhDDepartment of Infectious Diseases
Research interests: control of inflammatory responses
Clayton W. Naeve, PhDChief Information Officer, Information Sciences
Research interests: bioinformatics, high-throughput biotechnologies
Fariba Navid, MDDepartment of Oncology
Research interests: treatment of pediatric sarcomas and melanoma
Geoffrey Neale, PhDHartwell Center for Bioinformatics & Biotechnology
Kirsten K. Ness, PT, PhDDepartment of Epidemiology & Cancer Control
Research interests: functional limitations among cancer survivors
Arthur W. Nienhuis, MDDepartment of Hematology
Research interests: genetic therapy of hematological diseases
Leta K. Nutt, PhDDepartment of Biochemistry
Research interests: metabolic regulation of apoptosis; calcium homeostasis during apoptosis; metabolic regulation of ER stress
Stacey K. Ogden, PhDDepartment of Biochemistry
Research Interest: mechanisms of Hedgehog signal transduction in development and disease
Robert J. Ogg, PhDDepartment of Radiological Sciences
Research interests: brain function of survivors of childhood diseases
Rohit P. Ojha, DrPHDepartment of Epidemiology & Cancer Control
Research interests: Prediction of outcomes and late-effects among cancer survivors
Guillermo Oliver, PhDDepartment of Genetics
Research interests: development of the CNS and lymphatic vasculature
Arzu Onar-Thomas, PhDDepartment of Biostatistics
Research interests: Ph I-II designs, bioinformatics, survival analy
Joseph T. Opferman, PhDDepartment of Biochemistry
Research interests: regulation of cell death during hematopoiesis
Brent A. Orr, MD, PhDDepartment of Pathology
Research interests: molecular classification of tumors of the nervous system
Atmaram S. Pai Panandiker, MDDepartment of Radiological Sciences
Research interests: Generation of novel therapies in the context of molecular targeted and other multidisciplinary trials
Alberto Pappo, MDDepartment of Oncology
Research Interests: Development of novel therapies for pediatric solid tumors with special interest in: pediatric melanoma; soft tissue sarcomas; pediatric gastrointestinal stromal tumors
Janet F. Partridge, PhDDepartment of Biochemistry
Research interests: chromosome segregation, heterochromatin assembly
Zoltán Patay, MD, PhDDepartment of Radiological Sciences
Research interests: multimodality tumor tissue characterization by MRI
Junmin Peng, PhDDepartment of Structural Biology
Research interests: Proteomics to ubiquitin biology and human disease
Sean Phipps, PhDDepartment of Psychology
Research interests: coping and adjustment in children with cancer
Asha B. Pillai, MDDepartment of Bone Marrow Transplantation & Cellular Therapy
Research interests: immunoregulatory cell networks; prevention of graft-versus-host disease (GVHD); immune mechanisms of separation of GVT from GVHD
Philip M. Potter, PhDDepartment of Chemical Biology & Therapeutics
Research interests: anticancer drug hydrolysis by carboxylesterases
Stan Pounds, PhDDepartment of Biostatistics
Research interests: develop statistical methods for genomics studies
Ching-Hon Pui, MDDepartment of Oncology
Research interests: biology and treatment of childhood leukemia
Ibrahim Qaddoumi, MD, MSDepartment of Oncology
Research interests: low grade gliomas as unique diseases; advancing study of pediatric brain tumors in developing countries through international collaboration, twinning, and telemedicine
Richard Rahija, DVM, PhDAnimal Resource Center
Bhaskar N. Rao, MDDepartment of Surgery
Research interests: surgical management of sarcomas and rare tumors
Wilburn E. Reddick, PhDDepartment of Radiological Sciences
Research interests: white matter injury and neurocognitive functioning
Mary V. Relling, PharmDDepartment of Pharmaceutical Sciences
Research interests: pharmacokinetics and genetics of leukemia therapy
Raul C. Ribeiro, MDDepartment of Oncology
Research interests: international outreach, hematological malignancies
Giles W. Robinson, MDDepartment of Oncology
Research interests: Origin and genomics of medulloblastoma, translational studies
Leslie L. Robison, PhDDepartment of Epidemiology & Cancer Control
Research interests: pediatric cancer epidemiology and outcomes
Charles O. Rock, PhDDepartment of Infectious Diseases
Research interests: membrane phospholipid metabolism
Martine F. Roussel, PhDDepartment of Tumor Cell Biology
Research interests: genes and microRNAs in brain tumors
Jeffrey E. Rubnitz, MD, PhDDepartment of Oncology
Research interests: treatment of acute myeloid leukemia
Noah D. Sabin, MD, JDDepartment of Radiological Sciences
Research interests: the imaging of brain tumors and neuroimaging of long-term survivors of childhood cancer
John T. Sandlund, MDDepartment of Oncology
Research interests: clinical and biologic investigation of NHL and ALL
John A. Sandoval, MDDepartment of Surgery
Research interests: Pediatric surgical oncology
Victor M. Santana, MDDepartment of Oncology
Research interests: novel therapeutics, neuroblastoma, research ethics
Erin G. Schuetz, PhDDepartment of Pharmaceutical Sciences
Research interests: mechanisms of human variation in drug response
John D. Schuetz, PhDDepartment of Pharmaceutical Sciences
Research interests: regulation and function of ABC transporters
Brenda Schulman, PhDDepartment of Structural Biology
Research interests: cellular regulation by ubiquitin-like proteins
Anang A. Shelat, PhDDepartment of Chemical Biology & Therapeutics
Research interests: Multi-scale modeling of biological and chemical data
Charles J. Sherr, MD, PhDDepartment of Tumor Cell Biology
Research interests: tumor suppressor-dependent signaling networks
David R. Shook, MDDepartment of Bone Marrow Transplantation and Cellular Therapy
Research interests: Transplantation for solid tumors; cellular therapy
Barry L. Shulkin, MDDepartment of Radiological Sciences
Research interests: PET CT imaging and evaluation of pediatric tumors
Ronald L. Smith, MHAVice President for Scientific Operations
Scott E. Snyder, PhDDepartments of Radiological Sciences and Chemical Biology & Therapeutics
Research interests: design of radioactive drugs for medical imaging
David J. Solecki, PhDDepartment of Developmental Neurobiology
Research interests: cell polarity in neuron precursor differentiation
Brian P. Sorrentino, MDDepartment of Hematology
Research interests: gene therapy and hematopoietic stem cell biology
Alex Sparreboom, PhDDepartment of Pharmaceutical Sciences
Research interests: drug intake carriers in kidney and liver
Sheri L. Spunt, MDDepartment of Oncology
Research interests: soft tissue sarcomas of childhood
Ashok Srinivasan, MDDepartment of Bone Marrow Transplant & Cellular Therapy
Research interests: infections in the immune-compromised host
Deo Kumar Srivastava, PhDDepartment of Biostatistics
Research interests: clinical trials, robust methods, survival analysis
Clinton F. Stewart, PharmDDepartment of Pharmaceutical Sciences
Research interests: pharmacology of anticancer drugs in children
J. Paul Taylor, MD, PhDDepartment of Developmental Neurobiology
Research interests: To understand the roles of catabolic pathways
Michael R. Taylor, PhDDepartment of Chemical Biology & Therapeutics
Research interests: using zebrafish to study the development, maintenance, and function of the blood-brain barrier; model pediatric brain tumors; perform high-throughput small molecule screens
Brandon Triplett, MDDepartment of Bone Marrow Transplant & Cellular Therapy
Research interests: Hematopoietic cell transplant for high risk leukemia; Use of alternative donors in patients lacking a fully matched sibling donor; Immune reconstitution following hematopoietic cell transplant
Vida L. Tyc, PhDDepartment of Psychology
Research interests: health behavior trials, tobacco control
Dario A. A. Vignali, PhDDepartment of Immunology
Research interests: regulatory T cells and T-cell signaling
Dana Wallace, MSAdministration, Comprehensive Cancer Center
Thomas R. Webb, PhDDepartment of Chemical Biology & Therapeutics
Research interests: Synthetic organic chemistry–based drug discovery
Cynthia Wetmore, MD, PhDDepartment of Oncology
Research interests: Developmental therapeutics, Phase I/II studies in neuro-oncology
Stephen White, DPhilDepartment of Structural Biology
Research interests: structural analysis of catalysis and DNA repair
Matthew W. Wilson, MDDepartment of Surgery
Research interests: surgical ophthalmology
Karen D. Wright, MDDepartment of Oncology
Research interests: Ependymoma, atypical teratoid rhabdoid tumors, infant brain tumors
Jianrong (John) Wu, PhDDepartment of Biostatistics
Research interests: design and analysis of preclinical and clinical trials
Jun J. Yang, PhDDepartment of Pharmaceutical Sciences
Research interests: the genomics of hematologic tumors, with particular interests in genomic characterization of inter-patient variability in anti-leukemia drug response and disease susceptibility
Stanislav S. Zakharenko, MD, PhDDepartment of Developmental Neurobiology
Research interests: synaptic and neuronal mechanisms of schizophrenia
Gerard P. Zambetti, PhDDepartment of Biochemistry
Research interests: p53 function in tumor suppression and tumorigenesis
Jinghui Zhang, PhDDepartment of Computational Biology
Research interest: computational methods for cancer genomics
Jie Zheng, PhDDepartment of Structural Biology
Research interests: protein NMR and structure-based drug discovery
Jian Zuo, PhDDepartment of Developmental Neurobiology
Research interests: hair cell function and regeneration in mice