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Solid Tumor : Wilms tumor
Phase III study for Stage III/IV Wilms tumor with favorable histology. This means that the cancer cells look almost like normal cells in the kidney when looked under a microscope by a pathologist, but there is residual tumor in the abdomen or metastases (spread) to other sites in the body. There are two treatment questions on this study. For patients with tumor that has spread only to the lungs, we will evaluate how the tumors responded to chemotherapy after 6 weeks. If the lung tumors have resolved, the patient will not receive lung radiation. If the lung tumors have not resolved or if the cancer has spread to other sites, the patient will receive more intensified therapy including lung radiation.
The second treatment question is to determine if patients with specific genetic changes in their tumor have an improved outcome (better survival) when treated with more intensive chemotherapy. Treatment on this study for all participants will last about 6-8 months.
For the current eligibility status of this clinical study, referring physicians must contact St. Jude Children's Research Hospital at 1-866-2ST-JUDE (1-866-278-5833).
Rachel Brennan, MD
St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105 USA
Voice: 1-888-226-4343 or 901-595-4055
Referring or consulting physicians only: firstname.lastname@example.org
For all other inquiries about St. Jude Children's Research Hospital studies: email@example.com
The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.