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Finding Cures. Saving Children.
Brain Tumor Protocols / Clinical Studies
For more information on any of the protocols listed below, please contact:
Amar Gajjar, MD
Director of Neuro-Oncology
Tabatha Doyle, RN
Coordinator, Brain Tumor Program
Contact us anytime, 24 hours a day, 7 days a week.
Phase I Study of the Combination of Vandetanib and Dasatinib Administered During and After Radiation Therapy in Children with Diffuse Intrinsic Pontine Glioma
For: Diffuse intrinsic pontine glioma
A Phase I/II Trial of a New Tyrosine Kinase Inhibitor (Tarceva; Erlotinib Hydrochloride; OSI-774) during and after Radiotherapy in the Treatment of Patients with Newly Diagnosed High-Grade Glioma and Unfavorable Low-Grade Glioma
For: Intracranial high-grade glioma and unfavorable low-grade glioma
Treatment of Patients with Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor (PNET), or Atypical Teratoid Rhabdoid Tumor (ATRT)
For: Medulloblastoma, supratentorial primitive neuroectodermal tumor (PNET), atypical teratoid rhabdoid tumor (ATRT), ependymoblastoma, pineoblastoma, central nervous system (CNS) neuroblastoma
Risk-Adapted Therapy for Children Less Than 3 Years of Age with Embryonal Brain Tumors, High-Grade Glioma, Choroid Plexus Carcinoma or Ependymoma
For: Embryonal brain tumors, choroid plexus carcinoma or ependymoma
Non St. Jude Protocols
A Phase II Study of Conformal Radiotherapy in Patients with Low-Grade Gliomas (ACNS0221)
For: Central Nervous System Tumors
Phase III Radiotherapy Alone vs. Chemotherapy Followed by Response-based Radiotherapy for Newly Diagnosed Primary CNS Germinoma (ACNS0232)
For: Germinoma
Cilengitide (EMD 121974) (IND# 59073) in Recurrent or Progressive and Refractory Childhood High-Grade Glioma
For: Gliomas
A Phase I Pharmacokinetic Optimal Dosing Study of Intraventricular Topotecan for Children with Neoplastic Meningitis
For: Neoplastic meningitis
A Phase I Clinical Trial of AZD2171 In Children With Recurrent or Progressive Central Nervous Systems (CNS) Tumors
For: Recurrent or Progressive Central Nervous System (CNS) Tumors
Phase II study of Bevacizumab plus Irinotecan (Camptosar) in Children with Recurrent, Progressive, or Refractory Malignant Gliomas, Diffuse/Intrinsic Brain Stem Gliomas, Medulloblastomas, Ependymomas and Low Grade Gliomas
For: Gliomas
Phase I and Pharmacokinetic Study of Enzastaurin (LV317615) in Children and Adolescents with Refractory Primary CNS Tumors
For: Brain tumors
A Phase 1 study of MK-0752 in Pediatric Patients with Recurrent or Refractory CNS Malignancies
For: Brain tumors
A Phase I Pharmacokinetic and Safety Study in Children with Recurrent or Refractory Medulloblastoma to Identify a Pharmacokinetic Based Dose for GDC-0449
For: Brain tumors
