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Charles J. Sherr, M.D., Ph.D., to receive the Prize for Scientific Excellence in Medicine by the American-Italian Cancer Foundation.
St. Jude Children’s Research Hospital scientist named to honorary society.
Charles Sherr, M.D., Ph.D., of St. Jude Children’s Research Hospital, is honored by the AACR Academy for his scientific contributions to advancing understanding and treatment of cancer.
Charles Sherr, MD, PhD, co-chair of Genetics and Tumor Cell Biology at St. Jude Children’s Research Hospital and a Howard Hughes Medical Institute Investigator, has been awarded the distinction of American Association for the Advancement of Science (AAAS) Fellow. AAAS is the world’s largest general scientific society.
St. Jude investigators provide strong evidence for why the targeted therapy drug imatinib (Gleevec™) is often unable to prevent relapse of a particularly aggressive form of acute lymphoblastic leukemia (ALL).
St. Jude researchers prepare to knock out a rare form of leukemia.
Loss of Arf gene in acute lymphoblastic leukemia makes some forms of this cancer resistant to treatment with imatinib; but blocking JAK kinases can restore the sensitivity of cells to this drug.
Charles J. Sherr, M.D., Ph.D., of St. Jude Children's Research Hospital, has been elected to the Institute of Medicine (IOM), a prestigious branch of the National Academy of Sciences.
Charles Sherr, M.D., Ph.D., a member of the Genetics & Tumor Cell Biology Department at St. Jude and a Howard Hughes Medical Institute investigator, is one of two scientists world wide to receive the prestigious Landon-AACR Prize for Cancer Research.
Researchers discovered that the Arf gene was once moderately effective in slowing down cellular reproduction until it linked up with a more efficient set of genes to create a powerful anti-cancer response. Arf have evolved to slow the cell's metabolism and growth by limiting production of ribosomes, which guide production of all other cellular proteins.