Non-Therapeutic Protocol
MTRPAL: Motor Proficiency and Physical Activity in Adult Survivors of Childhood ALL
Type of Protocol/Clinical Study
Supportive Studies: Long Term Effects
Description
Childhood ALL (acute lymphoblastic leukemia) survivors are at increased risk for early mortality, second malignancies, obesity and heart disease, often unavoidable because of either the effects of the cancer or the treatment required for cure. Long-term outcomes are also influenced by lifestyle choices, and may be exacerbated in ALL survivors whose physical disabilities prevent participation in regular physical activity.
The study will compare percent body fat, muscle strength, ankle joint flexibility, feeling in arms and legs, and ability to exercise in a group of adult ALL survivors to a group of healthy volunteers from the community.
Objective
To provide comprehensive and objective information on impairments of musculoskeletal health, sensory function, and fitness among a large group of childhood ALL survivors, and to define high risk groups by assessing treatment factors that contribute to impaired function.
Eligibility
ALL Survivors
- Survivor of childhood ALL who was treated at St. Jude Children's Research Hospital between 1980 and 1999
- At least ten years from diagnosis of ALL
- At least 18 years of age at the time of the scheduled evaluation
Comparison Group
- Sibling, parent, relative or friend of a current or former St. Jude patient
- At least 18 years of age at the time of the scheduled evaluation
Exclusion Criteria
- Down Syndrome or congenital cognitive, musculoskeletal or cardiopulmonary impairments that interfere with motor function
- Currently pregnant or lactating
- Undergoing active treatment for cancer
Principal Investigator
Kirsten Ness, PT, PhD
The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.