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A new study indicates that hydroxyurea, a drug proven to help prevent the excruciating pain crises of sickle cell disease in adults, is a potential treatment for infants with the genetic disorder.
PTEN, a tumor-suppressor gene that when mutated leads to brain tumors and other cancers, causes neurons in the brain to grow larger, not multiply, a recent study shows.
Growing Up With HIV/AIDS: Issues in Prevention and Quality of Life seeks to improve the quality, appropriateness and effectiveness of health care and community support for the growing numbers of adolescents and children infected and affected by HIV/AIDS.
A St. Jude immunologist describes that understanding intricate chemical warfare between host cells and invaders could lead to development of a new category of drugs that help cells resist infection.
The discovery of the abnormal fusion of two gene segments will help scientists readily diagnose a rare form of childhood cancer and may help lead to a cure.
Hydroxyurea is a chemotherapy drug that has been used for more than 30 years to treat certain types of cancer.
Children whose treatment for acute lymphoblastic leukemia (ALL) causes them to stop growing can safely regain height with growth hormone (GH) shots, according to scientists.
Scientists studying links between genetic mutations and breast cancer have confirmed a protein's role in halting replication of abnormal DNA at cell-cycle checkpoints.
An ongoing study at St. Jude Children's Research Hospital indicates that a new treatment protocol could increase survival rates for some pediatric brain cancers to 80 percent for high-risk and 90 percent for standard-risk.
Male mice lacking two genes important for the control of the cell cycle will be infertile, a study published today shows. Females are not affected by this genetic deficiency.
Survivors of childhood acute lymphoblastic leukemia (ALL) are at a greater risk for developing osteoporosis, or reduced bone density, according research from St. Jude Children's Research Hospital.
The genetic basis for why some people do not express, or produce, CYP3A5, a specific protein that helps the body metabolize one half of all drugs, including many anti-cancer drugs and organ rejection drugs, has been identified by researchers ...
The first medical conference to focus on the emerging field of stem cells for tissue transplant will be held in New Orleans March 22 - 24.
The long-term effects of the hepatitis C virus (HCV) in former childhood cancer patients are the focus of current studies at St. Jude Children's Research Hospital.
Transplantation of bone marrow mesenchymal cells has the potential to correct inherited disorders of bone, cartilage and muscle, according to a study by researchers at St. Jude Children's Research Hospital, published in the March issue of Blood.
Completion of the human genome project will influence the general framework for anticancer drug development but not fundamentally alter it any time soon predict two cancer specialists in a commentary in the March issue of Nature Medicine.
St. Jude Children's Research Hospital, in collaboration with GlaxoSmithKline and the National Institutes of Health (NIH), was awarded a $2.4 million grant for the development of a new drug active against multi-drug resistent tuberculosis.