Children with anxious personalities are more likely to experience symptoms of post-traumatic stress than childhood cancer survivors, St. Jude researchers report.

St. Jude Children’s Research Hospital and the University of Florida Proton Therapy Institute have formed a collaboration to provide proton therapy for St. Jude patients. The announcement follows the approval of the first clinical study to evaluate the use of proton therapy for rare brain cancers in children younger than 3 years old.

Arthur Nienhuis, M.D., of St. Jude Children’s Research Hospital, is the recipient of the 2009 Mentor Award from the American Society of Hematology (ASH).

The heart of the 13th Annual St. Jude Cancer Survivors Conference was sandwiched between an opening night of karaoke and a Saturday afternoon carnival with 138 childhood cancer survivors accompanied by 320 family members taking part this year.

Four years after Brenda Schulman, PhD, Structural Biology and Genetics and Tumor Cell Biology, set out to explore the universe within the APC, her team recently sent back its first dispatch from the frontier.

Patients with the genetic foundation to marshal an efficient, rapid response to the H5N1 influenza virus are more likely than others to survive the bird flu, according to a team led by St. Jude investigators.

A team led by St. Jude researchers recently identified a gene pivotal for immune system balance. Ultimately, the discovery may aid efforts to tame allergies and asthma.

St. Jude took another step in the shift from paper to electronic health records August 19 when chemotherapy orders from the Solid Tumor Clinic stopped coming in by fax and began arriving in the pharmacy electronically.

Researchers have uncovered the first cases in which HIV almost certainly was transmitted from mothers or other caregivers to children through pre-chewed food.

The most comprehensive analysis yet of the genome of childhood acute myeloid leukemia (AML) found only a few mistakes in the genetic blueprint, suggesting the cancer arises from just a handful of missteps, according to new findings from St. Jude Children’s Research Hospital.

The molecular machinery that helps brain cells migrate to their correct place in the developing brain has been identified by St. Jude scientists. The finding offers new insight into the forces that drive brain organization in developing fetuses and children during their first years.

The most comprehensive study yet of long-term survivors of childhood central nervous system (CNS) tumors details risks some survivors face decades after their diagnosis, prompting a renewed call for improved follow-up care.

Childhood acute lymphoblastic leukemia (ALL) can be successfully treated using a carefully personalized chemotherapy regimen without cranial radiation, investigators at St. Jude Children's Research Hospital have found. Such radiation of the brain was once a standard ALL treatment to prevent recurrence of the leukemia in the central nervous system (CNS).

Researchers comparing the fetal development of the eye of the owl monkey with that of the capuchin monkey have found that only a minor difference in the timing of cell proliferation can explain the multiple anatomical differences in the two kinds of eyes.

In a new study of adults who survived cancer as children, St. Jude researchers have found that many survivors lead sedentary lifestyles and are more likely to be less physically active than their siblings.

Every cell in the body arises from the process of cell division—an intricate molecular process in which a cell precisely copies its gene-containing chromosomes and segregates them into identical parcels that migrate into the two new daughter cells. Malfunction of this segregation machinery can have profound consequences.

As the world watches the developing story of the influenza A (H1N1) outbreak, St. Jude Children’s Research Hospital is working collaboratively with other research centers to help develop an effective vaccine.

Cells isolated from the eye that many scientists believed were retinal stem cells are, in fact, normal adult cells, investigators at St. Jude have found. If retinal stem cells could be obtained, they might provide the basis for treatments to restore sight to millions of people with blindness caused by retinal degeneration.

St. Jude researchers have discovered a key factor of fatal influenza virus infection that suggests a possible new way to treat the disease and to greatly reduce the death toll of a potential worldwide pandemic like the 1918 Spanish flu.

Oncologists frequently use combinations of chemotherapy drugs as a knockout punch against tumors. The strategy has proven successful because it aims to jam the machinery of cancer cells in ways that are synergistic—fighting cancers more effectively than the individual drugs could alone.

White blood cells called neutrophils and macrophages are the first responders of the immune system. They serve as the first line of defense against invading microbes—identifying them, engulfing them and eliminating them.

For the first time, St. Jude researchers have identified a subtype of acute T-lymphoblastic leukemia (T-ALL) that is resistant to standard chemotherapy. They are planning to use this new insight to diagnose the disease in children with the subtype and to use bone marrow transplants to more effectively treat the disease.

Even though women treated for childhood cancers with chest radiation suffer a high risk of breast cancer, they are far less likely to begin recommended early mammogram screening than they should, researchers found.

St. Jude researchers have discovered a chain of biochemical events that compromise the liver’s capacity to adequately clear many prescription drugs from the bodies of fetuses, young children and patients with liver cancer and other hepatic disorders.

When newly created proteins emerge from the cell’s protein-making machinery, they appear as useless, spaghetti-like strands. Only after these strands fold into their intricate, final globular shapes can proteins begin their work as enzymes and other essential cellular components.