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Howard: Complete List of Publications



Paley MS, Meehan EJ, Rosenberger FE, Howard SC, Harris JM. Synthesis and characterization of a novel betaine dye: 2,4-dimethyl-6-(2,4,6-triphenyl-N- pyridinio)phenolate. J Organic Chem 1989; 54:3432.

Paley MS, McGi1l RA, Howard SC, Wallace SE, Harris JM. Solvatochromism. A new method for polymer characterization. Macromolecules 1990; 23(21):4557-4564.

Herman M, Glass T, Howard SC. Case Records of LeBonheur Children's Medical Center: A seventeen month old female with abdominal distension and portal vein gas. Pediatric Emergency Care 1997; 13(3):237-242.

Willner IR, Uhl MD, Howard SC, Williams EQ, Riely CA, Waters B. Serious hepatitis A: an analysis of patients hospitalized during an urban epidemic in the United States. Ann Intern Med 1998; 128(2):111-114.

Howard SC, Gajjar A, Ribeiro RC, Rivera GK, Rubnitz J, Sandlund JT, Harrison PL, de Armendi A, Dahl GV, Pui C-H. Safety of lumbar puncture for children with acute lymphoblastic leukemia and thrombocytopenia. JAMA 2000; 284(17):2222-2224.

McCarville B, Hoffer FA, Howard SC, Goloubeva O, Kauffman W. Hepatic veno-occlusive disease in children undergoing bone-marrow transplantation: usefulness of sonographic findings. Pediatr Radiol 2001; 31:102-105.

Howard SC, Gajjar AJ, Cheng C, Kritchevsky SB, Somes GW, Harrison PL, Ribeiro RC, Rivera GK, Rubnitz JE, Sandlund JT, Armendi AJ de, Razzouk BI, Pui C-H. Traumatic lumbar puncture in pediatric patients with acute lymphoblastic leukemia. JAMA 2002; 288:2001-2007.

Crews K, Wimmer P, Howard SC, Razzouk B. Pharmacokinetics of 2-CDA in a pediatric patient undergoing hemofiltration and hemodialysis for acute renal failure. J Pediatr Hematol Oncol 2002; 24:677-680.

Howard SC, Pui C-H. Endocrinopathy in children with acute lymphoblastic leukemia. Blood Reviews 2002; 16:225-243.

Howard SC, Armendi AJ, Pui C-H. Racial difference in rates of traumatic lumbar puncture (letter). JAMA 2003; 289:548-549.

Howard SC, Kaplan SD, Razzouk BI, Sandlund JT, Ribeiro RC, Gajjar AJ, Skoch JP, Roy III S, Hudson M, Pui C-H. Urolithiasis in pediatric patients with acute lymphoblastic leukemia. Leukemia 2003; 17:541-546.

Pui C-H, Sandlund JT, Pei D, Rivera GK, Howard SC, Ribeiro RC, Rubnitz JE, Razzouk BI, Hudson M, Cheng C, Raimondi SC, Behm FG, Downing J, Relling MV, Evans WE. Recent improvements in therapy for acute lymphoblastic leukemia extend to black children. JAMA 2003; 290:2001-2007.

Metzger M, Howard SC, Fu LC, Peña A, Stefan R, Hancock ML, Zhang Z, Pui C-H, Wilimas J, Ribeiro RC.  Improving the outcome of childhood acute lymphoblastic leukemia in countries with limited resources: insights from Honduras. Lancet 2003; 362:706-708.

Howard SC, Naidu PE, Hu XJ, Jeng MR, Rodriguez-Galindo C, Rieman MD, Wang WC. The natural history of moderate aplastic anemia in children. Pediatr Blood Cancer 2004; 43:545-551.

Howard SC, Pedrosa M, Lins M, Pedrosa A, Pui CH, Ribeiro RC, Pedrosa F. Establishment of a pediatric oncology program and outcomes of childhood acute lymphoblastic leukemia in a resource-poor area. JAMA 2004; 291:2471-2475.

Pui CH, Sandlund JT, Pei D, Campana D, Rivera GK, Ribeiro RC, Rubnitz JE, Razzouk BI, Howard SC, Hudson MM, Cheng C, Kun LE, Raimondi SC, Behm FG, Downing JR, Relling MV, Evans WE. Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St. Jude Children's Research Hospital. Blood 2004; 104:2690-2696.

El Saleeby CM, Howard SC, Hayden R, McCullers JA. Association between tea ingestion and invasive Bacillus cereus infection in children with cancer: a case control study. CID 39:1536-1539; 2004.

Hijiya N, Metzger ML, Pounds S, Schmidt JE, Razzouk BI, Rubnitz JE, Howard SC, Nunez CA, Pui C-H, Ribeiro RC. Severe cardiopulmonary complications consistent with systemic inflammatory response syndrome caused by leukemia cell lysis in childhood acute myelomonocytic or monocytic leukemia. Pediatr Blood Cancer 2004; 43:1-7.

Tamburro RF, Gordon PL, D’Apolito JP, Howard SC. Unsafe and violent behavior in commercials aired during televised major sporting events. Pediatrics 2004; 114(6):e694-698.

Hudson MM, Krasin M, Link MP, Donaldson SS, Billups C, Merchant TE, Kun L, Billet AL, Kaste S, Tarbell NJ, Howard S, Friedmann AM, Hurwitz CA, Young JA, Marcus KC, Rai S, Cowan T, Weinstein HJ. Risk-adapted combined modality therapy with VAMP/COP and response-based, involved-field radiation for unfavorable pediatric Hodgkin’s disease. J Clin Oncol 2004; 22:4541-4550.

Hijiya N, Onciu M, Howard SC, Zhang Z, Cheng C, Sandlund JT, Kyzer EP, Behm FG, Pui C-H. Utility of automated counting to determine absolute neutrophil counts and absolute phagocyte counts for pediatric cancer treatment protocols. Cancer 2004; 101:2681-2686.

Relling MV, Yang W, Das S, Cook EH, Rosner GL, Neel M, Howard S, Ribeiro R, Sandlund JT, Pui C-H, Kaste SC. Pharmacogenetic risk factors for osteonecrosis of the hip among children with leukemia. J Clin Oncol 2004; 22:3930-3936.

Howard SC, Wilimas JA. Delays in diagnosis and treatment of childhood cancer: Where in the world are they important? Pediatr Blood Cancer 2005; 44:1-2.

Kaste SC, Howard SC, McCarville EB, Krasin MJ, Kogos PG, Hudson MM. 18F-FDG-avid sites mimicking active disease in pediatric Hodgkin’s. Pediatric Radiology 2005; 35:141-154.

Sandlund JT, Howard SC, Hijiya N, Pui C-H, Shenep JL, Adderson EE. Myositis complicating Viridans streptococcal sepsis in childhood leukemia. Pediatr Blood Cancer 2005; 44:1-3.

Howard SC, Campana D, Coustan-Smith E, Antillon F, Bonilla M, Fu L, Pui, C-H., Ribeiro RC, Wilimas JA, Lorenzana R. Development of a regional flow cytometry center for diagnosis of childhood leukemia in Central America. Leukemia 2005; 19:323-325.

Antillon F, Baez FL, Barr R, Barrantes Zamorra JC, Fu Carrasco L, Moreno B, Bonilla MM, Tognoni G, Valsecchi MG, Howard S, Ribeiro RC, Masera G. AMOR: A proposed cooperative effort to improve outcomes of childhood cancer in Central America. Pediatr Blood Cancer 2005; 45(2):107-10.

Howard SC, Ribeiro RC, Pui C-H. Strategies to improve outcomes of children with cancer in low-income countries. Eur J Cancer 2005; 41(11):1584-1587.

Krasin MJ, Rai SN, Kun LE, Merchant TE, Metzger ML, Howard SC, Hudson MM Patterns of treatment failure in pediatric and young adult patients with Hodgkin's disease: local disease control with combined-modality therapy. J Clin Oncol 2005; 23(33):8406-13.

Rech A, de Carvalho GP, Meneses CF, Hankins J, Howard S, Brunetto AL. The influence of traumatic lumbar puncture and timing of intrathecal therapy on outcome of pediatric acute lymphoblastic leukemia. Pediatr Hematol Oncol 2005; 22(6):483-488.

Hijiya N, Liu W, Sandlund JT, Jeha S, Razzouk BI, Ribeiro RC, Rubnitz JE, Howard SC, Kyzer EP, Redd DS, Cheng C, Rivera GK, Hudson MM, Relling MV, Pui C-H. Overt testicular disease at diagnosis of childhood acute lymphoblastic leukemia: Lack of therapeutic role of local irradiation. Leukemia 2005; 19(8):1399-403.

Pui C-H, Pei D, Sandlund JT, Campana D, Ribeiro RC, Razzouk BI, Rubnitz JE, Howard SC, Hijiya N, Jeha S, Cheng C, Downing JR, Evans WE, Relling MV, Hudson M. Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia. J Clin Oncol 2005; 23(31):7936-41.

Sanders RP, Maddirala SD, Geiger TL, Pounds S, Sandlund JT, Ribeiro RC, Pui C-H, Howard SC. Premedication with acetaminophen or diphenhydramine for transfusion with leucoreduced blood products in children. Br J Haematol 2005; 130(5):781-787.

Quintana Y, Howard S, Norland M, Patel A, O'Brien R, Ribeiro R. Pond4Kids - a multi-site online Pediatric Oncology Research Database for collaborative protocol research. AMIA Annu Symp Proc. 2005; 1090.

Metzger ML, Howard SC, Hudson MM, Gow KW, Li C-S, Krasin MJ, Merchant T, Kun L, Shelso J,  Pui C-H, Shochat SJ, McCarville MB. Natural history of thyroid nodules in survivors of pediatric Hodgkin lymphoma. Pediatr Blood Cancer 2006; 46(3):314-319.

Reddick WE, Shan ZY, Glass JO, Helton S, Xiong X, Wu S, Bonner MJ, Howard SC, Christensen R, Khan RB, Pui C-H, Mulhern RK. Smaller white matter volumes are associated with larger deficits in attention and learning among long-term survivors of acute lymphoblastic leukemia. Cancer 2006; 106(4):941-9.

Bachir H, Mot S, Metzger ML, Howard SC, Kaste S, Krasin MP, Hudson MM. Itraconazole-enhanced chemotherapy toxicity in a patient with Hodgkin lymphoma. J Pediatr Hematol Oncol 2006; 28(1):33-35.

Hendrick JM, Kaste SC, Tamburro RF, Hoffer FA, Onciu M, Sandlund JT, Ribeiro RC, Chandler JC, Howard SC. Abdominal compartment syndrome in a newly diagnosed patient with Burkitt lymphoma. Pediatr Radiol 2006; 36(3):254-257.

Karimova EJ, Rai SN, Ingle D, Ralph AC, Deng X, Neel MD, Howard SC, Pui CH, Kaste SC. MRI of knee osteonecrosis in children with leukemia and lymphoma: part 2, clinical and imaging patterns. AJR Am J Roentgenol 2006; 186(2):477-82.

Metzger ML, Hudson MM, Somes GW, Shorr RI, Li C-S, Krasin MJ, Shelso J, Pui C-H, Howard SC. White race as a risk factor for hypothyroidism after treatment for pediatric Hodgkin's lymphoma. J Clin Oncol 2006; 24:1516-1521.

Howard SC, Pui C-H. Pitfalls in predicting tumor lysis syndrome. Leuk Lymph 2006 47(5):782-785.

DiSessa TG, Howard SC, Salim MA. Congenital right ventricular diverticulum associated with a ventricular septal defect: a rare echocardiographic finding. Echocardiography 2006; 23(9):787-9.

Caniza M, Clara W, Maron G, Navarro-Marin JE, Rivera R, Howard SC, Camp J, Barfield RC. Establishment of ethical oversight of human research in El Salvador: lessons learned. Lancet Oncol 2006; 7(12):1027-1033

Franklin J, Pluetschow A, Paus M, Specht L, Anselmo A-P, Aviles A, Biti G, Bogatyreva T, Bonadonna G, Brillant C, Cavalieri E, Diehl V, Eghbali H, Fermé C, Henry-Amar M, Hoppe R, Howard S, Meyer R, Niedzwiecki D, Pavlovsky S, Radford J, Raemaekers J, Ryder D, Schiller P, Shakhtarina S, Valagussa P, Wilimas J, Yahalom J. Second malignancy risk associated with treatment for Hodgkin lymphoma: meta-analysis of the randomised trials. Ann Oncol 2006; 17(12):1749-1760.

Hijiya N, Panetta JC, Zhou Y, Kyzer EP, Howard SC, Jeha S, Razzouk BI, Ribeiro RC, Rubnitz JE, Hudson MM, Sandlund JT, Pui C-H, Relling MV. Body mass index does not influence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemia. Blood 2006; 108(13):3997-4002.

Jeha S, Behm F, Pei D, Sandlund JT, Ribeiro RC, Razzouk BI, Rubnitz JE, Hijiya N, Howard SC, Cheng C, Pui C-H. Prognostic significance of CD20 expression in childhood B-cell precursor acute lymphoblastic leukemia. Blood 2006; 108(10):3302-3304.

Geiger TL, Howard SC. Acetaminophen and diphenhydramine premedication for allergic and febrile non-hemolytic transfusion reactions: Good prophylaxis or bad practice? Transfusion Med Rev 2007; 21(2):1-12.

Howard SC, Marinoni M, Castillo L, Bonilla M, Tognoni G, Antillon F, Valsecchi MG, Pui C-H, Ribeiro RC, Sala A, Barr RD, Masera G, MISPHO Consortium. Improving outcomes for children with cancer in low income countries in Latin America: A report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO) – PART 1. Pediatr Blood Cancer 2007; 48:364-369.

Howard SC, Ortiz R, Baez F, Cabanas R, Barrantes JC, Fu L, Pena A, Samudio A, Vizcaino M, Rodriguez-Galindo C, Masera G, Barr RD, MISPHO Consortium. Protocol-based treatment for children with cancer in low income countries in Latin America: A report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO) - PART 2. Pediatr Blood Cancer 2007; 48:486-490.

Howard SC, Wilimas JA, Flores A, Pacheco C, de Reyes G, Machin S, Svarch E, Navarrete M, Nieves R, Rodriguez H, Masera G, MISPHO Consortium. Treatment for children with severe aplastic anemia and sickle cell disease in low income countries in Latin America. A report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO): PART III. Pediatr Blood Cancer 2007; 48(5):598-599.

Ayoub L, Fú L, Peña A, Sierra JM, Dominguez PC, Pui C-H, Quintana Y, Rodriguez A, Barr RD, Ribeiro RC, Metzger ML, Wilimas JA, Howard SC. Implementation of a data management program for pediatric cancer units in low-income countries: Tegucigalpa, Honduras. Pediatr Blood Cancer 2007; 49:23-27.

Sanders RB, Geiger TL, Heddle N, Pui C-H, Howard SC. A revised classification scheme for acute transfusion reactions. Transfusion 2007; 47(4):621-628.

Leander C, Fu LC, Peña A, Howard SC, Rodriguez-Galindo C, Wilimas JA, Ribeiro RC, Haik B. Impact of an education program on late diagnosis of retinoblastoma in Honduras. Pediatr Blood Cancer 2007; 49:817-819.

Bachir H, Hudson MM, Kaste SC, Howard SC, Krasin M, Metzger ML. Pericardial involvement at diagnosis in pediatric Hodgkin lymphoma patients. Pediatr Blood Cancer 2007; 49(5):598-599.

Karimova EJ, Rai SN, Howard SC, Neel M, Britton L, Pui CH, Kaste SC.. Femoral head osteonecrosis in pediatric and young adult patients with leukemia or lymphoma. J Clin Oncol 2007; 25(12):1525-1531.

Hsu S, Metzger ML, Hudson MM, Pedrosa F, Lins M, Barros C, Maciel K, Pui C-H, Ribeiro RC, Howard SC. Comparison of treatment outcomes of childhood Hodgkin lymphoma in two US centers and a center in Recife, Brazil. Pediatr Blood Cancer 2007; 49(2):139-144.

Conklin HM, Khan RB, Reddick WE, Helton S, Brown R, Howard SC, Bonner M, Christensen R, Wu S, Xiong X, Mulhern RK. Acute neurocognitive response to methylphenidate among survivors of childhood cancer: a randomized, double-blind, cross-over trial. J Pediatr Psychol 2007; 32(9):1127-1139.

Inaba H, Jenkins JJ, McCarville MB, Morrison RR, Howard SC, Pui C-H, Ribeiro RC. Pulmonary alveolar proteinosis in pediatric leukemia. Pediatr Blood Cancer 2007; 51(1):66-70.

Howard SC, Metzger ML, Wilimas JA, Quintana Y, Pui C-H, Robison LL, Ribeiro RC. Childhood cancer epidemiology in low-income countries. Cancer 2008; 112:461-472.

Pui C-H., Howard SC. The challenges of central nervous system disease in pediatric leukemia. Lancet Oncology 2008; 9:257-268.

Marchese VG, Connolly BH, Able C, Booten AR, Bowen P, Porter BM, Rai SN, Hancock ML, Pui C-H, Howard S, Neel MD, Kaste SC. Relationships among severity of osteonecrosis, pain, range of motion, and functional mobility in children, adolescents, and young adults with acute lymphoblastic leukemia. Phys Therapy 2008; 88(3):341-350.

Rubnitz JE, Howard SC, Willis J, Pui C-H, Pounds S, Hayden RT. Baseline mannose binding lectin levels may not predict infection among children with leukemia. Pediatr Blood Cancer 2008; 50(4):866-868.

Martin MB, Li C-S, Rowland CC, Howard SC, Kaste SC. Correlation of bone age, dental age, and chronological age in survivors of childhood acute lymphoblastic leukemia. Int J Paediatr Dentistry 2008; 18:217-223.

Roberson JR, Raju S, Shelso J, Pui C-H, Howard SC. Diabetic ketoacidosis during therapy for childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 2008; 50(6):1207-1212.

Metzger ML, Castellino S, Hudson MM, Rai S, Kaste S, Krasin MJ, Kun L, Pui C-H, Howard SC. Effect of race on the outcome of pediatric patients with Hodgkin lymphoma. JCO 2008; 26(8):1282-1288.

Tamburro RF, Barfield RC, Shaffer ML, Rajasekaran S, Woodard P, Morrison RR, Howard SC, Fiser RT, Schmidt JC, Sillos EM. Changes in outcomes (1996-2004) for pediatric oncology and hematopoietic stem cell transplant patients requiring invasive mechanical ventilation. Pediatr Crit Care Med 2008; 9(3):270-277.

Hines-Thomas M, Kaste SC, Hudson MM, Howard SC, Liu WA, Wu J, Kun LE, Shulkin BL, Krasin MJ, Metzger ML. Comparison of gallium and PET scans at diagnosis and follow-up of pediatric patients with Hodgkin lymphoma. Pediatr Blood Cancer 2008; 51:198-203.

Ribeiro RC, Steliarova-Foucher E, Magrath I, Lemerle J, Eden T, Forget C, Mortara I, Tabah-Fish I, Divino JJ, Miklavec T, Howard SC, Cavalli F. A descriptive study of the baseline status of pediatric oncology in 10 low- or mid-income countries receiving “My Child Matters” support. Lancet Oncol 2008; 9(8):721-729.

Quintana Y, O’Brien R, Patel A, Becksfort J, Shuler A, Nambayan A, Ogdon D, Chantada G, Howard SC, Ribeiro RC. Cure4Kids: Research challenges in the design of a website for global education and collaboration. Information Design Journal 2008; 16(3):243-249.

Howard SC, Pui C-H, Ribeiro RC. Components of cure: treatment of acute lymphoblastic leukemia in Indonesia and other low-income countries. Pediatr Blood Cancer 2008; 51(6):719-721.

Kellie SJ, Howard SC. Global child health priorities: what role for pediatric oncologists? Eur J Cancer 2008; 44(16):2388-96.

Jasper BW, Conklin HM, Lawford J, Morris EB, Howard SC, Wu S, Xiong X, Shelso J, Khan RB. Growth effects of methylphenidate among childhood cancer survivors: a 12-month case-matched open-label study. Pediatr Blood Cancer 2009; 52(1):39-43.

Roberson JR, Shelso J, Zhou Y, Inaba H, Metzger ML, Ribeiro RC, Sandlund JT, Jeha S, Pui C-H, Howard SC. Clinical consequences of hyperglycemia during remission induction for pediatric acute lymphoblastic leukemia. Leukaemia 2009; 23(2):245-50.

Hunger SP, Sung L, Howard SC. Treatment strategies and regimens of graduated intensity for childhood acute lymphoblastic leukemia in low-income countries: a proposal. Pediatr Blood Cancer 2009; 52:559-565.

Gupta S, Bonilla M, Fuentes SL, Caniza M, Howard SC, Barr R, Greenberg ML, Ribeiro R, Sung L. Incidence and predictors of treatment related mortality in pediatric acute leukemia in El Salvador. Br J Cancer 2009; 100:1026-1031.

Pui C-H, Campana D, Pei D, Bowman WP, Sandlund JT, Kaste SC, Ribeiro RC, Rubnitz JE, Raimondi SC, Onciu M, Coustan-Smith E, Kun LE, Jeha S, Cheng C, Howard SC, Simmons V, Bayles Amy, Metzger ML, Boyett JM, Leung W, Downing JR, Evans WE, Relling MV. Treatment of childhood acute lymphoblastic leukemia without prophylactic cranial irradiation. NEJM 2009; 360:2730-2741.

Conklin HM, Lawford J, Jasper BW, Morris EB, Howard SC, Ogg SW, Wu S, Xiong X, Khan RB. Side effects of methylphenidate in survivors of childhood cancer: a randomized placebo-controlled trial. Pediatrics 2009; 124:226-33.

Baskin JL, Pui C-H, Reiss U, Wilimas JA, Metzger ML, Ribeiro RC, Howard SC. Management of central venous catheter occlusions and related complications. Lancet 2009; 374:159-169.

Jeha S, Pei D, Raimondi SC, Onciu M, Campana D, Cheng C, Sandlund JT, Ribeiro RC, Rubnitz JE, Howard SC, Downing JR, Evans WE, Relling MV, Pui C-H. Increased risk for CNS relapse in pre-B cell leukemia with the t(1;19)/TCF3-PBX1. Leukemia 2009; 23:1406-9. PMID: 19282835

Bhojwani D, Howard SC, Pui C-H. High risk childhood acute lymphoblastic leukemia. Clinical Myeloma and Leukemia 2009. Clin Lymphoma Myeloma. 2009; 9:S222-S230. PMID: 19778845

Spraker HL, Spyridis G, Pui C-H, Howard SC. Conservative management of pancreatic pseudocysts in children with acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2009; 31(12):957-959. PMID 19956023

Crews KR, Zhou Y, Pauley J, Howard SC, Jeha S, Relling MV, Pui C-H. Effect of allopurinol versus urate oxidase on methotrexate pharmacokinetics in children with newly diagnosed acute lymphoblastic leukemia. Cancer 2010; 116(1):227-232. PMID: 19834958

Pui CH, Pei D, Campana D, Bowman WP, Sandlund JT, Kaste SC, Ribeiro RC, Rubnitz JE, Coustan-Smith E, Jeha S, Cheng C, Metzger ML, Bhojwani D, Inaba H, Raimondi SC, Onciu M, Howard SC, Leung W, Downing JR, Evans WE, Relling MV. Improved prognosis for older adolescents with acute lymphoblastic leukemia. J Clin Oncol 29(4):386-391, 2011.

Pui C-H, Pei D, Sandlund JT, Ribeiro RC, Rubnitz JE, Raimondi SC, Onciu M, Campana D, Kun LE, Jeha S, Cheng C, Howard SC, Metzger ML, Bhojwani D, Downing JR, Evans WE, Relling MV. Long-term results of St. Jude Total Therapy studies 11, 12, 13A, 13B and 14 for childhood acute lymphoblastic leukemia. Leukemia 2010; 24(2):371-382. PMID: 20010620

Conklin HM, Khan RB, Reddick WE, Ashford J, Ogg S, Howard SC, Morris EB, Brown R, Bonner M, Christensen R, Wu S, Xiong X, Mulhern RM. Long-term efficacy of methylphenidate in enhancing attention regulation, social skills and academic abilities of childhood cancer survivors. JCO 2010; 28(29):4465-72.

Metzger ML, Hudson MM, Krasin MJ, Kaste SC, Kun LE, Sandlund JT, Howard SC. Initial response to salvage therapy determines prognosis in relapsed pediatric Hodgkin lymphoma patients. Cancer 2010; 116(18):4376-84.

Hines-Thomas M, Howard SC, Hudson MM, Krasin MJ, Kaste SC, Metzger ML. Utility of bone marrow biopsy at diagnosis in pediatric Hodgkin lymphoma. Haematologica 2010; 95(10):1691-6.

Kawedia JD, Kaste SC, Pei D, Panetta JC, Cai X, Cheng C, Neale G, Howard SC, Evans WE, Pui CH, Relling MV. Pharmacokinetic, pharmacodynamic, and pharmacogenetic determinants of osteonecrosis in children with acute lymphoblastic leukemia. Blood 117(8):2340-2347, 2011.

Quintana Y, Patel AN, Naidu PE, Howard SC, Antillon FA, Ribeiro RC. POND4Kids: a web-based pediatric cancer database for hospital-based cancer registration and clinical collaboration. Stud Health Technol Inform 164:227-231, 2011.

Gupta S, Antillon FA, Bonilla M, Fu L, Howard SC, Ribeiro RC, Sung LL. Treatment-related mortality in children with acute lymphoblastic leukemia in Central America. Cancer 117(20):4788-4795, 2011.

Sandlund JT, Pui CH, Mahmoud H, Zhou Y, Lowe E, Kaste S, Kun LE, Krasin MJ, Onciu M, Behm FG, Ribeiro RC, Razzouk BI, Howard SC, Metzger ML, Hale GA, Rencher R, Graham K, Hudson MM. Efficacy of high-dose methotrexate, ifosfamide, etoposide and dexamethasone salvage therapy for recurrent or refractory childhood malignant lymphoma. Ann Oncol 22(2):468-471, 2011.

Brennan RC, Helton KJ, Pei D, Cheng C, Inaba H, Metzger ML, Howard SC, Rubnitz JE, Ribeiro RC, Sandlund JT, Jeha S, Pui CH, Bhojwani D. Spinal epidural lipomatosis in children with hematologic malignancies. Ann Hematol 90(9):1067-1074, 2011.

Howard SC, Jones DP, Pui CH. The tumor lysis syndrome. N Engl J Med 364(19):1844-1854, 2011.

Howard SC, Jones DP, Pui CH. The tumor lysis syndrome - reply to letter. N Engl J Med 365(6):573-574, 2011.

Inaba H, Bhojwani D, Pauley JL, Pei D, Cheng C, Metzger ML, Howard SC, Rubnitz JE, Sandlund JT, Ribeiro RC, Leung W, Campana D, Pui CH, Jeha S. Combination chemotherapy with clofarabine, cyclophosphamide, and etoposide in children with refractory or relapsed haematological malignancies. Br J Haematol August 25, 2011.

Bhojwani D, Pei D, Sandlund JT, Jeha S, Ribeiro RC, Rubnitz JE, Raimondi SC, Shurtleff S, Onciu M, Cheng C, Coustan-Smith E, Bowman WP, Howard SC, Metzger ML, Inaba H, Leung W, Evans WE, Campana D, Relling MV, Pui CH. ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy. August 26, 2011.

Carr S, Allison KJ, Van De Velde LA, Zhang K, English EY, Iverson A, Daw NC, Howard SC, Navid F, Rodriguez-Galindo C, Yang J, Adderson EE, McCullers JA, Flynn PM. Safety and immunogenicity of live attenuated and inactivated influenza vaccines in children with cancer. J Inf Dis 204(10):1475-1482, 2011.

Denburg AE, Joffe S, Gupta S, Howard SC, Ribeiro RC, Antillon FA, Vasquez R, Sung LL. Pediatric oncology research in low income countries: ethical concepts and challenges. Pediatr Blood Cancer (58)4:492-7, 2012.

Gupta S, Bonilla M, Valverde P, Fu LG, Howard SC, Ribeiro RC, Sung L. Treatment-related mortality in children with acute myeloid leukaemia in Central America: incidence, timing and predictors. Eur J Cancer 48(9):1363-9, 2012.

Baskin JL, Reiss U, Wilimas JA, Metzger ML, Ribeiro RC, Pui C-H, Howard SC. Thrombolytic therapy for central venous catheter occlusion. Haematologica 2012; 97(5):641-650. PMID:22180420

Metzger ML, Weinstein HJ, Hudson MM, Billett AL, Larson EC, Friedmann A, Howard SC, Donaldson SS, Krasin MJ, Kun LE, Marcus KJ, Yock TI, Tarbell N, Billups CA, Wu J, Link MP. Results of a prospective clinical trial of VAMP with or without radiation based on early response for children with very low risk Hodgkin lymphoma. JAMA 2012; 307(24):2609-2616. PMID:22735430

Christensen AM, Pauley JL, Molinelli AR, Panetta JC, Ward DA, Stewart CF, Hoffman JM, Howard SC, Pui C-H, Pappo AS, Relling MV, Crews KR. Resumption of high-dose methotrexate after acute kidney injury and glucarpidase use in pediatric oncology patients. Cancer 2012;118(17):4321-30. PMID: 22252903

Lins MM, Amorim M, Vilela P, Viana M, Ribeiro RC, Pedrosa A, Lucena-Silva N, Howard SC, Pedrosa F. Risk factors for delayed diagnosis of childhood leukemia in Pernambuco, Brazil. Delayed Diagnosis of Leukemia and Association With Morbid-Mortality in Children in Pernambuco, Brazil. J Pediatr Hematol Oncol 2012;34:e271-6 PMID: 22935656

Hicks JK, Crews KR, Hoffman JM, Kornegay NM, Wilkinson MR, Lorier R, Stoddard A, Yang W, Smith C, Fernandez CA, Cross SJ, Haidar C, Baker DK, Howard SC, Evans WE, Broeckel U, Relling MV. A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record. Clin Pharmacol Ther 2012 Nov; 92(5):563-6 PMID:22990750

McCullers JA, Williams BF, Wu S, Smeltzer MT, Williams BF, Hayden R, Howard SC, Pui C-H, Hughes WT. Health care-associated infections at a children’s cancer hospital, 1983-2008. J Ped Infect Dis Soc, 2012; 1(1): 26-34

Inaba H, Surprise HC Pounds S, Cao X, Howard SC, Ringwald-Smith K, Buaboonnam J, Dahl G, Bowman WP, Taub JW, Campana D, Pui C-H, Ribeiro RC, Rubnitz JE. Effect of body mass index on the outcome of children with acute myeloid leukemia. Cancer 2012 118(23):5989-96. PMID:22648558

Gavidia R, Fuentes SL, Vasquez R, Bonilla M, Ethier MC, Diorio C, Caniza M, Howard SC, Sung L. Low socioeconomic status is associated with prolonged times to assessment and treatment, sepsis and infectious death in pediatric fever in El Salvador. PLoS One 2012; 7(8):e43639. Epub 2012 August 22. PMID:22928008

Day SW, McKeon LM, Garcia J, Wilimas JA, Carty RM, de Alarcon P, Antillon F, Howard SC. Use of joint commission international standards to evaluate and improve pediatric oncology nursing care in Guatemala. Pediatr Blood Cancer 2012; Epub doi: 10.1002/pbc.24318. PMID:23015363

Marjerrison S, Antillon F, Fu L, Martinez R, Vasquez R, Bonilla M, Howard SC, Sung L. Outcome of children treated for relapsed acute lymphoblastic leukemia in Central America. Cancer 2012 Epub Nov 16. doi: 10.1002/cncr.27846. PMID: 23165914

Bhakta N, Martiniuk AL, Gupta S, Howard SC. The cost-effectiveness of treating paediatric cancer in low-income and middle-income countries: a case-study approach using acute lymphocytic leukaemia in Brazil and Burkitt lymphoma in Malawi. Arch Dis Child epub 10.1136/archdischild-2011-301419. PMID: 23201550.

Baskin JL, Lezcano E, Kim BS, Figueredo D, Lassaletta A, Perez-Martinez A, Madero L, Caniza MA, Howard SC, Samudio A, Finlay JL. Management of children with brain tumors in Paraguay. Neuro Oncol 2012 epub 11/29/12. PMID: 23197688