Yan: Complete List of Publications



Zhou HY, Zhang W, Yan B.* Use Cyclohexylisocyanide and Methyl 2-Isocyanoacetate as Convertible Isocyanides for Microwave-Assisted Fluorous Synthesis of 1,4-Benzodiazepine-2,5-DioneLibrary. J Comb Chem 2009 (in press).

Mu QX, Broughton DL, Yan B.* Endosomal leakage and Nuclear Translocation of Multiwalled Carbon Nanotubes: Developing a Model for Cell Uptake. Nano Letters 2009 (in press).

Liu AF, Zhou HY, Su GX, Zhang W, Yan B.* Microwave-Assisted Fluorous Synthesis of 1,4-Benzodiazepine-2,5-Dione Library. J Comb Chem 11(6), 1083-1093, 2009.

Zhai SM, Yang L, Cui QZC, Sun Y, Dou QP*, Yan B.* Tumor Cellular Proteasome Inhibition and Growth Suppression by 8-Hydroxylquinoline and Clioquinol Requires Their Capabilities to Bind Copper and Transport Copper into Cells. J Biological Inorganic Chemistry Web Publication Date: Oct. 7, 2009.

Milacic V, Jiao PF, Zhang B, Yan B*, Dou QP.* Novel 8-Hydroxylquinoline Analogs Induce Copper-Dependent Proteasome Inhibition and Cell Death in Human Breat Cancer Cells. International Journal of Oncology 2009 (in press).

Zhang B, Yan B.*Analytical Strategies for Characterizing Nanoparticle's Surface Chemistry. Analytical and Bioanalytical Chemistry. Web Publication Date: Aug 1, 2009.

Luo M*, Yan B.*A Simple Synthesis of Octaphenylcyclotetra(Siloxane). Tetrahedron Letters 50(37), 5208-5209, 2009.

Mu QX, Du GQ, Chen TS, Zhang B, Yan B.* Suppression of Human Bone Mophorgenetic Protein (BMP) Signaling by Carboxylated Single-Walled Carbon Nanotubes. ACS Nano 3(5), 1139-1144, 2009.

Zhang B, Xing YH, Zhou HY, Li ZW, Mu QX, Yan B.* Functionalized Carbon Nanotubes Specifically Bind to Chymotrypsin Catalytic Site and Regulate its Enzymatic Function. Nano Letters 9(6), 2280-2284, 2009.

Zhang Q, Feng W, Zhou HY, Yan B.* Advances in Preclinical Small Molecules for the Treatment of Non-Small Cell Lung Cancer. Expert Opinion on Therapeutic Patents 19(6), 731-751, 2009.

Qu G, Bai Y, Zhang Y, Jia Q, Zhang W, Yan B*. The effect of multiwalled carbon nanotube agglomeration on their accumulation in and damage to organs in mice. Carbon 47, 2060-2069, 2009.

Mu Q, Li Z, Li X, Mishra SR, Zhang B, Si Z, Yang L, Jiang W, Yan B*. Characterization of Protein Clusters of Diverse Magnetic Nanoparticles and Their Dynamic Interactions with Human Cells. J Phys Chem C 113 (14), 5390–5395, 2009.

Ma XF, Shi RR, Zhang B, Yan B.* Kinetics of Resin-Supported Mitsunobu Esterification and Etherification Reactions. J Comb Chem 11 (3) 438-445, 2009.

Du FF, Zhou HY, Chen LX, Zhang B, Yan B*. Structure Elucidation of Nanoparticle-Bound Organic Molecules By 1H NMR. Trends in Analytical Chemistry 28(1), 88-95, 2009.

Zhou HY, Du FF, Li X, Zhang B, Li W, Yan B*. Characterization of Organic Molecules Attached to Gold Nanoparticle Surface Using High Resolution Magic Angle Spinning 1H NMR. J Phys Chem C 112 (49) 19360-19366, 2008.

Yu YM, Zhang Q, Mu QX, Zhang B, Yan B*. Exploring the Immunotoxicity of Carbon Nanotubes. Nanoscale Research Letters 3, 271-277, 2008.

Lemoff A, Yan B*. Dual Detection Approach to a More Accurate Measure of Relative Purity in High-Throughput Characterization of Compound Collections. J Comb Chem 10(5), 746-751, 2008.

Qi M, Zhou H, Ma X, Zhang B, Jefferies C, Yan B*. Feasibility of a Self-Calibrated LC/MS/UV Method to Determine the Absolute Amount of Compounds in Their Storage and Screening Lifecycle. J Comb Chem 10 (2), 162-165, 2008.

Zhou H, Mu Q, Gao N, Liu A, Xing Y, Gao S, Zhang Q, Qu G, Chen Y, Liu G, Zhang B, Yan B*. A Nano-Combinatorial Library Strategy for the Discovery of Nanotubes with Reduced Protein-Binding, Cytotoxicity, and Immune Response. Nano Lett 8(3), 859-865, 2008. 

Zhou H, Wu S, Zhai S, Liu A, Sun Y, Li R, Zhang Y, Ekins S, Swaan PW, Fang B, Zhang B, Yan B*. Design, Synthesis, Cytoselective Toxicity, Structure-Activity Relationships, and Pharmacophore of Thiazolidinone Derivatives Targeting Drug-Resistant Lung Cancer Cells. J Med Chem 51, 1242-1251, 2008.

Mu Q, Liu W, Xing Y, Zhou H, Li Z, Zhang Y, Ji L, Wang F, Si Z, Zhang B, Yan B*. Protein Binding by Functionalized Multiwalled Carbon Nanotubes Is Governed by the Surface Chemistry of Both Parties and the Nanotube Diameter. J Phys Chem C 112(9), 3300-3307, 2008.

Zhang B, Li X, Yan B*. Advances in HPLC detector-towards universal detection. Anal Bioanal Chem 390(1), 299-301, 2008.

Zhou H, Liu A, Li X, Ma X, Feng W, Zhang W, Yan B*. Microwave-Assisted Fluorous Synthesis of 2-Aryl-Substituted 4-Thiazolidinone and 4-Thiazinanone Libraries. J Comb Chem 10(2), 303-312, 2008.

Yu Z, Wang F, Milacic V, Li X, Cui QC, Zhang B, Yan B*, Dou QP.* Evaluation of copper-dependent proteasome-inhibitory And apoptosis-inducing activities of novel Pyrrolidine dithiocarbamate analogues. Int J Mol Med 20: 919-925, 2007.

Xu P, Qiu JH, Zhang YN, Chen J, Wang PG, Yan B, Song J, Xi Ri M, Deng ZX, Ma CQ. Efficient whole-cell biocatalytic synthesis of N-acetyl-D-neuraminic acid. Advanced Synthesis & Catalysis 349(10), 1614-1618, 2007.

Yan B, Shi R, Zhang B, Kshirsagar T. A Kinetic Study of Product Cleavage Reactions from the Solid Phase by a Biocompatible and Removable Cleaving Reagent, HCl. J Combi Chem 9(4), 684-689, 2007.

Shi R, Wang F, Yan B. Site-Site Isolation and Site-Site Interaction - Two Sides Of the Same Coin. Int J Pept Res & Therapeutics 13(1-2), 213-219, 2007.

Chen D, Cui QC, Yang H, Barrea RA, Sarkar FH, Sheng S, Yan B, Reddy GPV, Dou QP. Cliquinol, a Therapeutic Agent for Alzheimer’s Disease, Has Proteasome-inhibitory, Apoptosis-inducing and Anti-tumor Activities in Human Prostate Cancer Cells and Xenografts. Cancer Res 67(4):1636-44, 2007.

Yan B, Zhao J, Leopold K, Zhang B, Jiang G. The Structure Dependent Response of Chemiluminescence Nitrogen Detector (CLND) for Organic Compounds with Adjacent Nitrogen Atoms Connected by a Single Bond. Anal Chem 79 (2) 718-726, 2007.

Daniel KG, Chen D, Yan B, Dou QP. Copper-binding compounds as proteasome inhibitors and apoptosis inducers in human cancer. Front Biosci 12:135-44, 2007.

Zhai S, Liu W, Yan B. Recent patents on treatment of severe acute respiratory syndrome (SARS). Recent Patents on Anti-Infective Drug Discovery 2(1), 1-10, 2007.

Chen L, Choo J, Yan B. The microfabricated electrokinetic pump: a potential promising drug delivery technique. Expert Opin Drug Deliv 4(2):119-129, 2007.

Landis-Piwowar KR, Milacic V, Chen D, Yang H, Zhao ZY, Chan TH, Yan B, Dou QP. Discovering novel anticancer drugs and chemo-sensitizers by using the proteasome as a potential target. Drug Resistance Update 9, 263-273, 2006.

Wu S, Guo W, Teraishi F, Pang J, Kaluarachchi K, Zhang L, Davis J, Dong F, Yan B, Fang B. Anticancer activity of 5-benzylidene-2-phenyllimino-1,3-thiazolidin-4-one (BPT) analogs. Med Chem 2(6):597-605, 2006.

Cheng X, Yan B, Gao L, Tang H, Fan Y, Anderson SN, Affleck R, Burns D. Compound transfer efficiency from polystyrene surfaces-application to microarrayed compound screening. J Biomolecular Screening 10(4), 293-303, 2005.

Yan B, Czarnik AW. Series Editors. Critical Review in Combinatorial Chemistry Volume 2. Armen M. Boldi, Editor, Combinatorial Synthesis of Natural Product Based Libraries by Taylor and Francis, 2005.

Yan B, Czarnik AW. Series Editors Critical Review in Combinatorial Chemistry Volume 1. Radislav A. Potyrailo,  Wilhelm Maier. Editors, Combinatorial and High-Throughput Discovery and Optimization of Catalysts and Materials by Taylor and Francis, 2005.

Irving M, Krueger CA, Wade JV, Hodges JC, Leopold K, Chan C, Shaqair S, Shornikov A, Stock M, Collins N, Yan B. High-Throughput Purification of Combinatorial Libraries II: Automated Separation of Single Diastereomers from a 1920-Member 4-Amidopyrrolidinone Library. J Combi Chem 6, 478-486, 2004.

Yan B, Collins N, Wheatley J, Irving M, Leopold K, Chan C, Shornikov A, Fang L, Lee A, Stock M, Zhao J. High-Throughput Purification of Combinatorial Libraries I: A High-Throughput Purification System Using an Accelerated Retention Window Approach. J Combi Chem 6, 255-261, 2004.

Fang L, Zhao J, Yan B. High throughput parallel LC/UV/MS analysis of combinatorial libraries in Methods in Enzymology Volume 369, Pages 3-21. Combinatorial Chemistry, Part B. Edited by: Guillermo A. Morales and Barry A. Bunin, 2003.

Yan B, Tang Q. Comparison of kinetics of organic reactions carried out on resin beads of different diameters. Industrial and Eng Chem Res 42 (24) 5964-5967, 2003.

Yan B. Editor. Chemical Analysis – A Series of Monographs on Analytical Chemistry and Its Applications Volume 163 “Analytical and purification methods in Combinatorial Chemistry” by John Wiley and Sons, Inc. 2003.

Yan B, Fang L, Irving M, Zhang S, Boldi AM, Woolard F, Johnson CR, Kshirsagar T, Figliozzi GM, Krueger CA, Collins N. Quality Control in Combinatorial Chemistry: Determination of the Quantity, Purity, and Quantitative Purity of Compounds in Combinatorial Libraries. J Combi Chem 5(5), 547-559, 2003.

Fang L, Demee M, Cournoyer J, Sierra T, Young C, Yan B. Parallel high-throughput accurate mass measurement using a nine-channel multiplexed electrospray LC/UV/TOFMS system. Rapid Commun Mass Spectr 17, 1425-1432, 2003.

Yan B. Monitoring and Optimizing Organic Reactions Carried Out on Solid Support. Chapter in book Polymeric Materials in Organic Synthesis and Catalysis. Buchmeiser, M. R. Ed. Wiley-VCH, 2003.

Yan B, Fang L, Irving M, Zhao J, Liu D, Figliozzi G, Woolard F, Krueger C. Analytical Methods for Optimization and Quality Control of Combinatorial Synthesis, chapter in Methods in Molecular Biology, Volume 201: Combinatorial Library Methods and Protocols, English, Lisa B. Ed. By Humana Press, 2002.

Fang L, Demee M, Sierra T, Zhao J, Tokushige D, Yan B. Optimization of an Eight-Channel Multiplexed Electrospray Time-of-Flight Mass Spectrometry (MUX-LCT) System for Combinatorial Library Analysis. Rapid Commun Mass Spectr 16, 1440-1447, 2002.

Yan B. Single bead analysis in combinatorial chemistry. Current Opinion in Chemical Biology 6, 328-332, 2002.

Fang L, Demee M, Sierra T, Kshirsagar T, Celebi A, Yan B. Kinetic Study of Amine Cleavage Reactions of Various Resin-Bound Thiophenol Esters from Marshall Linker. J Combi Chem 4, 362-368, 2002.

Cournoyer JJ, Kshirsagar T, Fantauzzi PP, Figliozzi GM, Makdessian T, Yan B. A Color Test for the Detection of Resin-Bound Aldehyde in Solid-Phase Combinatorial Synthesis. J Combi Chem 4, 120-124, 2002.

Irving MM, Kshirsagar T, Figliozzi GM, Yan B. Repeated Use of Solid Supports in Combinatorial Synthesis – The Case of Marshall Resin Recycling. J Combi Chem 3, 407-409, 2001.

Fang L, Pan J, Yan B. High-throughput determination of identity, purity and quantity of combinatorial library members using LC/MS/UV/ELSD. Bioeng Biotech (Combi Chem) 71, 162-171, 2001.

Yan B, Czarnik A. Editors Optimization of solid-phase combinatorial synthesis by Marcel Dekker, New York, 2001.

Irving M, Cournoyer J, Li R, Santos C, Yan B. Qualitative and Quantitative Analyses of Resin-Bound Organic Compounds. Combinatorial Chemistry and High-Throughput Screening 4, 353-362, 2001.

Yan B, Yan H. Combination of Single Bead FTIR and Chemometrics in Combinatorial Chemistry: Application of Multivariate Calibration Method in the Monitoring of Solid Phase Organic Synthesis. J Combi Chem 3, 78-84, 2001.

Yan B, Nguyen N, Liu L, Holland G, Raju B. Kinetic Comparison of Trifluoroacetic Acid Cleavage Reactions of Resin-Bound Carbamates, Ureas, Secondary Amides, and Sulfonamides from Benzyl-, Benzhydryl-, and Indole-Based Linkers. J Comb Chem 2(1) 66-74, 2000.

Gremlich HU, Yan B. Editors. Biological FTIR and Raman Spectroscopy by Marcel Dekker, New York, 2000.

Yan B. Analytical methods for combinatorial chemistry – a practical approach. In Combinatorial Chemistry – A Practical Approach by Oxford University Press, Edited by Hicham Fenniri, 2000.

Yan B. Vibrational spectroscopy for optimization of solid-phase organic synthesis. In Solid-Phase Organic Synthesis by John Wiley, Edited by Kevin Burgess, 1999.

Yan B, Gremlich H-U. The Role of FTIR Methods in the Rehearsal Phase of Combinatorial Chemistry. J Chromatography B 725, 91-102, 1999.

Yan B, Liu L, Astor CA, Tang Q. Determination of the Absolute Amount of Resin-Bound Hydroxyl or Carboxyl Groups for the Optimization of Solid-Phase Combinatorial and Parallel Organic Synthesis. Anal Chem 71(20) 4564-4571, 1999.

Yan B. Analytical methods in combinatorial chemistry by CRC Press (now Taylor & Francis), 1999.

Yan B, Martin PC, Lee J. Single Bead Fluorescence Microspectroscopy: Detection of Self-Quenching in Fluorescence-Labeled Resin Beads. J Combin Chem 1, 78-81, 1999.

Yan B, Gremlich H-U, Moss S, Coppola GM, Sun Q, Liu L. A comparison of various FTIR and FT raman methods: applications in the reaction optimization stage of combinatorial chemistry. J Combi Chem 1, 46-54, 1999.

Jackson JC, Vinluan CC, Dragland CJ, Sundararajan V, Yan B, Gounarides JS, Nirmala NR, Topiol S, Ramage P, Blume JE, Aicher TD, Bell PA, Mann WR. Heterologously expressed inner lipoyl domain of dihydrolipoyl acetyltransferase inhibits ATP-dependent inactivation of pyruvate dehydrogenase complex: Identification of important amino acid residues. Biochem J 334, 703-711, 1998.

Yan B. Monitoring the progress and the yield of solid-phase organic reactions directly on resin supports. Acct Chem Res 31, 621-630, 1998.

Yan B, Jewell Jr CF, Myers SW. Quantitatively monitoring of solid-phase organic synthesis by combustion elemental analysis. Tetrahedron 54, 11755-11766, 1998.

Li W, Yan B. Effects of Polymer Supports on the Kinetics of Solid-Phase Organic Reactions: A Comparison of Polystyrene- and TentaGel-Based Resins. J Org Chem 63, 4092-4097, 1998.

Sun Q, Yan B. Single bead IR monitoring a novel benzimidazole synthesis. Bioorg Med Chem Lett 8, 361-364, 1998.

Yan B, Sun Q. Crucial factors regulating site-interactions in resin supports determined by single bead IR. J Org Chem 63, 55-58, 1998.

Yan B. Properties of solid supports and their effects on solid-phase organic synthesis. Combinatorial Chemistry and High-Throughput Screening 1, 215-229, 1998.

Shapiro M, Lin M,  Yan B. Analytical Tools for Combinatorial Chemistry in (ACS Book) Combinatorial Chemistry: A Short Course, S. H. DeWitt and A. W. Czarnik, Editors, 1997.

Yan B, Li W. Rapid fluorescence determination of the absolute amount of aldehyde and ketone groups on resin supports. J Org Chem 62, 9354-9357, 1997.

Li W, Yan B. A direct comparison of the mixing efficiency in solid-phase organic synthesis by single bead IR and fluorescence spectroscopy. Tetrahedron Lett 38, 6485-6488, 1997.

Marti R, Yan B, Jarosinski M. Solid phase synthesis via 5-oxazolidinones. Ring opening reactions with amines and reaction monitoring by single bead FTIR microspectroscopy. J Org Chem 62, 5615-5618, 1997.

Lin SL, Yan B. Three dimentional model of sensory rhodopsin I reveals important restraints between the protein and the chromophore. Protein Engineering 10, 197-206, 1997.

Yan B, Spudich EN, Sheves M, Spudich JL. Complexation of the signal transducing protein HtrI to sensory rhodopsin I and its effect on thermodynamics of signaling state deactivation. J Phys Chem 101, 109-113, 1997.

Yan B, Gstach H. Monitoring of solid-phase heterocyclic chemistry by Single bead IR. Tetrahedron Lett 37, 8325-8328, 1996.

Yan B, Sun Q, Wareing JR, Jewell CF. Real-time Monitoring of the Catalytic Oxidation of Alcohols on Resin Supports by Single Bead FTIR Microspectroscopy. J Org Chem 61, 8765-8770, 1996.

Yan B, Kumaravel G. Probing solid-phase reactions by monitoring the IR bands of compounds on a single "flattened" resin bead. Tetrahedron 52, 843-848, 1996.

Yan B, Fell JB, Kumaravel G. Progression of organic reactions on resin supports monitored by single bead FTIR microspectroscopy. J Org Chem 61, 7467-7472, 1996.

Yan B, Spudich JL, Mazur P, Vunnam S, Derguini F, Nakanishi K. Spectral tuning in bacteriorhodopsin in the absence of counterion and coplanarization effects. J Biol Chem 270, 29668-29670, 1995.

Yan B, Kumaravel G, Anjaria H, Wu A, Petter RC, Jewell CF, Wareing J. Infrared spectrum of a single resin bead for real-time monitoring of solid-phase reactions. J Org Chem 60, 5736-5738, 1995.

Yan B, Mann WR, Bell P. Substrate-induced conformational changes in carnitine acetyltransferase. Biochim Biophys Acta 1253, 175-180, 1995.

Yan B, Xie A, Nienhaus GU, Katsuta Y, Spudich JL. Steric constraints in the retinal binding pocket of sensory rhodopsin I. Biochemistry 32, 10224-10232, 1993.

Yan B, Cline S, Doolittle WF, Spudich JL. Transformation of a BOP-HOP-SOP-I-SOP-II- Halobacterium halobium mutant to BOP+: effects of bacteriorhodopsin photoactivation on cellular proton fluxes and swimming behavior. Photochem Photobiol 56, 553-561, 1992.

Takahashi T, Yan B, Spudich JL. Sensitivity increase in the photophobic response of Halobacterium halobium reconstituted with retinal analogs: a novel interpretation for the fluence-response relationship and a kinetic modeling. Photochem Photobiol 56, 1119-1128, 1992.

Ratto GM, Robinson DW, B Yan, McNaughton PA. Development of the light response in neonatal mammalian rods. Nature 351, 654-657, 1991.

Yan B, Nakanishi K, Spudich JL. Mechanism of activation of sensory rhodopsin I: evidence for a steric trigger. Proc Natl Acad Sci USA 88, 9412-9416, 1991.

Yan B, Spudich JL. Evidence that the repellent receptor form of sensory rhodopsin I is an attractant signaling state. Photochem Photobiol 54, 1023-1026, 1991.

Yan B, Takahashi T, Johnson R, Spudich JL. Identification of signaling states of a sensory receptor by modulation of lifetimes of stimulus-induced conformations: the case of sensory rhodopsin II. Biochemistry 30, 10686-10692, 1991.

Yan B, Takahashi T, McCain DA, Rao VJ, Nakanishi K, Spudich JL. Effects of modifications of the retinal b-ionone ring on archaebacterial sensory rhodopsin I. Biophys J 57, 477-483, 1990.

Yan B, Takahashi T, Johnson R, Derguini F, Nakanishi K, Spudich JL. All-trans/13-cis isomerization of retinal is required for phototaxis signaling by sensory rhodopsins in halobacterium halobium. Biophys J 57, 807-814, 1990.

Takahashi T, Yan B, Mazur P, Derguini F, Nakanishi K, Spudich JL. Color regulation in the archaebacterial phototaxis receptor phoborhodopsin (sensory rhodopsin II). Biochemistry 29, 8467-8474, 1990.

Takahashi T, Yan B, Rao B, Nakanishi K, Spudich JL. Retinal analogs reconstitutions of bacterial sensory rhodopsin I. Biophys J 55, 383, 1989.


 


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