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Research
Research led by St. Jude Children’s Research Hospital investigators will likely impact how acute lymphoblastic leukemia is treated in young adults and shows older adolescent age does not dictate worse outcomes against the most common childhood cancer
International effort led by St. Jude Children’s Research Hospital scientists is expected to fuel development of targeted therapies and aid the search for unique combinations of cells and mutations that lead to other cancers
St. Jude Children’s Research Hospital investigators discuss results of research into managing iron overload associated with stroke prevention in young sickle cell patients and the search for genetic predictors of stroke risk
Vector-gene combination developed at St. Jude Children’s Research Hospital and UCL is central to latest clinical trial of gene therapy as a possible tool to provide long-term relief from disabling bleeds
The Intensive Care Unit (ICU) at St. Jude Children’s Research Hospital has been recognized for the second consecutive year with the Beacon Award for Critical Care Excellence given by the American Association of Critical-Care Nurses (AACN).
St. Jude Children’s Research Hospital scientists report new details about mechanisms regulating a crucial step in brain development, offering insight into the origins of epilepsy, mental retardation and possibly brain tumor metastasis.
In time for this year’s Great American Smokeout, St. Jude Children’s Research Hospital expands its smoking cessation efforts by offering free counseling and nicotine replacement therapy to survivors of childhood or adult-onset cancer
St. Jude Children’s Research Hospital has been named the recipient of the 2010 Omar N. Bradley Spirit of Independence Award, presented by the Independence Bowl Foundation.
At St. Jude Children’s Research Hospital a veteran investigator who oversees services and support essential to translating laboratory discoveries into better outcomes for patients is being honored for helping to train the next generation of research associates.
Investigators at the forefront of international efforts to decode the human genome and translate the findings into tools to better understand, find, treat and prevent cancer are scheduled to be at St. Jude Children’s Research Hospital for the Sixth Annual Biomedical Research Symposium Friday, October 1.
A new study led by St. Jude Children’s Research Hospital scientists signals hope for treatment of a neurodegenerative disease and a new model for understanding the mechanism at work in other more common neurodegenerative disorders.
Results help build a foundation for the next generation of therapies using cell-replacement strategies to restore vision lost to the retinal degeneration associated with glaucoma, diabetic retinopathy and age-related macular degeneration.
St. Jude Children’s Research Hospital scientists uncover a novel pathway for regulating T lymphocytes that play very different roles in inflammation. The mechanism offers a promising target for new drugs against autoimmune disorders.
Trial led by St. Jude Children’s Research Hospital investigators finds medication restores sustained attention of many young survivors; work begins on new strategies to help survivors cope with this common challenge.
St. Jude Children’s Research Hospital scientists discovered a new mechanism cells use to maximize production of a key protein following DNA damage and demonstrated the potential of small molecules to regulate the process and protect healthy tissue.
With its new expansion of the Pharmacogenomics Research Network (PGRN), the National Institutes of Health (NIH) awarded St. Jude Children’s Research Hospital a prestigious grant to focus on anticancer agent research in children. The five-year, $8.6 million grant is titled “PAAR4Kids—Pharmacogenomics of Anticancer Agents Research in Children.”
While September is Childhood Cancer Awareness Month nationwide, at St. Jude Children’s Research Hospital, the fight against this disease is a year-round mission.
Scientists have long recognized that cancers may look the same under the microscope, but carry different mutations, respond differently to treatment and result in vastly different outcomes for patients.
St. Jude Children's Research Hospital is ranked as one of the top institutions in the annual “Best Places to Work in Academia” list by The Scientist magazine. This is the fifth consecutive year St. Jude made the publication’s top 10 list of institutions in the United States. The hospital ranks second in the country behind Princeton University.
Acclaimed virologist Robert Webster, Ph.D., of St. Jude Children’s Research Hospital, presented the 2010 Leeuwenhoek prize lecture today, a prestigious recognition awarded by the Royal Society in London.
Childhood cancer survivors diagnosed later with non-melanoma skin cancer may be at increased risk for having a malignant tumor within 15 years, according to research led by St. Jude Children’s Research Hospital investigators.
Researchers from St. Jude Children’s Research Hospital and the Pediatric Brain Tumor Consortium (PBTC) presented today at the American Society of Clinical Oncology the findings of a pediatric brain tumor study using an experimental drug that targets the underlying genetic makeup of the tumor.
St. Jude Children's Research Hospital has been named the nation's top children's cancer hospital in the 2010-11 Best Children's Hospital rankings published in U.S. News & World Report. St. Jude received the best overall score summarizing quality of care.
An international team led by St. Jude Children’s Research Hospital investigators today released data detailing the effectiveness of nearly 310,000 chemicals against a malaria parasite that remains one of the world’s leading killers of young children.
The most comprehensive analysis yet of the genetic imbalances at the heart of childhood brain tumors known as high-grade gliomas (HGGs) identified a cancer gene that is unusually active in some tumors and is now the focus of a St. Jude Children’s Research Hospital clinical trial.
Social worker Judy Hicks of St. Jude Children's Research Hospital has been named the 2010 Social Worker of the Year by the Association of Pediatric Oncology Social Workers (APOSW).
More individualized therapy and better supportive care helped push the survival for children with acute myeloid leukemia (AML) to 71 percent three years after diagnosis, according to new research led by St. Jude Children’s Research Hospital investigators and reported in the medical journal The Lancet Oncology.
New evidence shows immunization against “swine flu” in 1976 might provide individuals with some protection against the 2009 pandemic H1N1 influenza virus, according to new research from St. Jude investigators.
St. Jude Children’s Research Hospital investigators have identified childhood cancer survivors who are at increased risk for deteriorating lung health, in part due to the lifesaving bone marrow transplants they underwent years earlier.
As physicians nationwide are acknowledged for their talent, sacrifice and courage on National Doctors’ Day, St. Jude Children’s Research Hospital honors its more than 230 staff and consulting physicians who strive to fulfill the hospital’s mission each day.
Investigators believe they have identified the founding member of a chemical family they hope will lead to a new class of cancer drugs, the first designed specifically against a childhood tumor, according to research led by St. Jude Children’s Research Hospital scientists.
St. Jude Children’s Research Hospital has partnered with the University of Tennessee Health Science Center (UTHSC) to appoint six distinguished physicians to St. Jude chairs in subspecialty areas that have been identified as key to continuing the advancement of treatment and research at St. Jude.
Ching-Hon Pui, MD, of St. Jude Children's Research Hospital, is being honored with the Clinical Excellence Award at the fifth annual National Physician of the Year Awards, organized by Castle Connolly Medical Ltd.
Scientists report a protein made by a gene already associated with a handful of human inflammatory immune diseases plays a pivotal role in protecting the intestinal tract from colitis.
A multicenter trial led by St. Jude Children’s Research Hospital investigators may change neutropenia treatment for all childhood cancer patients.
St. Jude Children’s Research Hospital and Washington University School of Medicine in St. Louis, today announced an unprecedented effort to identify the genetic changes that give rise to some of the world’s deadliest childhood cancers. The team has joined forces to decode the genomes of more than 600 childhood cancer patients who have contributed tumor samples for this historic effort.
New research suggests a family of widely used cholesterol-lowering drugs might help protect individuals from serious illness following bacterial infection, including the pneumococcal infections that pose a deadly threat to those with sickle cell disease.
