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It is virtually impossible to contract a disease from donating blood. Only sterile, disposable equipment is used throughout the donation process. You cannot get AIDS or another infectious disease by donating blood or blood products.
There are potential short-term side effects, however. These effects depend on the type of product being donated, your body's tolerance to the procedure, your overall health and your previous experiences with donations. Side effects can be minimized by being well-hydrated prior to donation, eating a well balanced meal before and after donation, and getting plenty of sleep the night before.
Common side effects may include dizziness, tingling in the lips and nose and chills. All of these side effects should pass shortly after donation.