2008 News Release Archive

 
12/29/2008
St. Jude ranked No. 1 pediatric oncology hospital

Parents magazine has named St. Jude Children’s Research Hospital as the No. 1 pediatric cancer care hospital in the country.

 
 
12/17/2008
Molecular marker identifies normal stem cells as intestinal tumor source (news release)

St. Jude scientists show for the first time that normal stem cells can act as the source of tumors in mature solid tissues.

 
 
12/03/2008
Gene therapy corrects sickle cell disease in laboratory study (news release)

New St. Jude treatment alleviates long-term anemia and organ damage in mice and paves the way for human applications.

 
 
12/01/2008
Reprogrammable cell type depends on a single gene to keep its identity (news release)

St. Jude study shows the Prox1 gene is a two-way switch that, if turned off, causes lymphatic endothelial cells to be reprogrammed so that they lose their identity and become more like blood endothelial cells.

 
 
12/01/2008
St. Jude identifies genomic causes of a certain type of leukemia relapse (news release)

Scientists at St. Jude Children’s Research Hospital have identified distinctive genetic changes in the cancer cells of children with acute lymphoblastic leukemia (ALL) that cause relapse.

 
 
11/19/2008
New insight into the controls on a go-to enzyme (news release)

Scientists at St. Jude have gained new insights into regulation of one of the body’s enzyme workhorses called calpains. As the cell’s molecular overachievers, calpains function in many cellular processes, including the movement of cells in tissues, the death of damaged cells, insulin secretion, and brain cell and muscle function.

 
 
11/03/2008
Parasites that live inside cells use loophole to thwart immune system

St. Jude Children's Research Hospital scientists have discovered a mechanism by which intracellular pathogens can shut down one of the body’s key chemical weapons against them: nitric oxide.

 
 
10/13/2008
Nobel Laureate Peter Doherty, PhD, elected to Institute of Medicine

Peter Doherty, PhD, of St. Jude Children’s Research Hospital, has been elected to the Institute of Medicine (IOM), a prestigious branch of the National Academy of Sciences.

 
 
09/19/2008
St. Jude study gives new insights into how cells accessorize their proteins (news release)

Researchers have determined how an enzyme that stitches all-important molecular adjustments onto proteins contorts itself to regulate its own function.

 
 
09/17/2008
St. Jude study finds treatment with new drug might make tumor cells more sensitive to therapy (news release)

Study shows treatment with a newly discovered drug could be useful in sensitizing tumor cells to therapeutic irradiation and potentially some chemotherapies.

 
 
08/11/2008
New insight into most common forebrain malformation (news release)

St. Jude scientists have identified one of the molecular mechanisms underlying the genetic brain malformation called holoprosencephaly (HPE). The findings not only yield insights into the most common developmental malformation of the anterior brain and face in newborns, but also help in understanding the intricate process by which the brain forms in the developing fetus.

 
 
07/07/2008
St. Jude study reveals a new function for an old enzyme in fatal childhood disease (news release)

A ubiquitous housekeeping enzyme has been found to play a major role in keeping the bone marrow environment healthy so it can nurture hematopoietic stem cells.

 
 
07/07/2008
St. Jude study reveals a new function for an old enzyme in fatal childhood disease (news release)

A ubiquitous housekeeping enzyme has been found to play a major role in keeping the bone marrow environment healthy so it can nurture hematopoietic stem cells.

 
 
05/29/2008
St. Jude finds young age may give survival advantage to children with certain brain tumors (news release)

The improved survival of children under 3 years old with diffuse pontine glioma compared to older children suggests that the biological properties of this cancer may be distinct in young patients.

 
 
05/12/2008
St. Jude study shows how T cell’s machinery dials down autoimmunity (news release)

Immune cells adjust their function like a radio dial, not an on/off light switch; a discovery that hints at how autoimmune disease may develop late in life.

 
 
05/09/2008
St. Jude receives NCI Comprehensive Cancer Center designation

St. Jude Children’s Research Hospital recently received the prestigious recognition of being designated as a National Cancer Institute (NCI) Comprehensive Cancer Center. The designation makes St. Jude the first and only cancer center solely focused on pediatric cancer to receive this distinction.

 
 
05/07/2008
St. Jude finds “dancing” hair cells are key to humans’ acute hearing (news release)

A new study shows how sounds are amplified in the inner ear, a finding that could explain how hearing loss can result from genetic mutation or overdose of drugs.

 
 
04/14/2008
St. Jude discovery offers new avenues to understanding an aggressive form of leukemia (news release)

Finding that a combination of genetic mutations can cause an aggressive form of acute lymphoblastic leukemia could lead to new cancer-fighting therapies.

 
 
03/24/2008
St. Jude study offers new hope for children with kidney tumors deemed inoperable (news release)

Physicians at St. Jude Children's Research Hospital have demonstrated that children with bilateral Wilms tumor, a cancer of the kidneys, can retain normal function in both kidneys by undergoing a procedure called bilateral nephron-sparing surgery, even when preoperative scans suggest that the tumors are inoperable.

 
 
03/20/2008
Molecular science could further improve leukemia survival, say St. Jude researchers (news release)

The dramatic increase that has occurred in the cure rate for children with acute lymphoblastic leukemia (ALL) will be difficult to replicate in older patients without considerable additional research.

 
 
03/14/2008
St. Jude finds signaling system that halts the growth of a childhood brain cancer (news release)

Researchers discover that proteins BMP2, BMP4 and BMP7 inhibit the growth of medulloblastoma tumors, while inducing malignant cells to develop into normal neurons, a finding that may lead to better treatments for the cancer.

 
 
02/29/2008
St. Jude researchers find key step in programmed cell death (news release)

The discovery provides insight into how certain proteins, including Hax1, work and how they control the process of apoptosis.

 
 
02/04/2008
St. Jude finds risk factors for severe RSV infection in immunocompromised children (news release)

Children receiving treatment for cancer who are under2 years and those with very low levels of immune system cells called lymphocytes are at higher risk for severe respiratory syncytial virus related disease.

 
 
01/16/2008
St. Jude defines eye cancer gene’s role in retinal development (news release)

Study provides the foundation for improving understanding of N-myc gene’s role in the eyes’ growth during fetal development when retinoblastoma forms.

 
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