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After identifying a protein that blocks death of high-risk acute lymphoblastic leukemia (ALL) cells, scientists use two-drug combination therapy to offer hope to children and adults with the disease. (Dr. Joseph Opferman)
St. Jude Children’s Research Hospital discovers a role for a protein in research that has implications for treatment of cancer and heart disease. (Dr. Joseph Opferman)
St. Jude Children’s Research Hospital discovery that a protein vital for cell survival and immune balance has another form with a different function could yield additional cancer treatment strategy. (Dr. Joseph Opferman)
For some, space may be the final frontier. But strange new worlds can also be found on a molecular level.
White blood cells called neutrophils and macrophages are the first responders of the immune system. They serve as the first line of defense against invading microbes—identifying them, engulfing them and eliminating them.
Joseph Opferman has been named a Pew Scholar in the Biomedical Sciences. The prestigious competitive awards provide flexible support to the scholars as they establish their laboratories and continue research in their areas of focus.
The series of steps by which stem cells give rise to all of the body's red and white blood cells and platelets has been discovered to depend on a single protein.