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Research
Assistant Member, St. Jude Faculty
Radiological Sciences
Radiation Oncology
Atmaram Pai Panandiker, MD
Radiological Sciences
MS 220, Room I-3124
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Email: atmaram.pai-panandiker@stjude.org
Phone: (901) 595-3226
FAX: (901) 595-3113
BA - The University of Texas at Austin
MD - The University of Texas School of Medicine at San Antonio (2002)
As a clinician-scientist, I am interested in research related to radiobiology and radiation parameters for treatment planning and delivery. With the intent to incorporate radio-sensitization experiments and anti-angiogenic/vasculogenic therapy into developmental clinical studies for selected solid tumors, I collaborate with basic and translational researchers at St. Jude and nationally. I study mechanisms to enhance radiosensitivity of these tumors using novel adjuvant and neo-adjuvant therapeutic agents.
Special Interests
Klimo P, Pai Panandiker AS, Thompson CJ, Boop FA, Qaddoumi I, Gajjar A, Armstrong GT, Ellison DW, Kun LE, Ogg RJ, Sanford RA. Management and outcome of pediatric focal low-grade brainstem tumors in pediatric patients: the St. Jude experience. J Neurosurg Pediatr. January 4, 2013.
DeWire MD, Beltran C, Boop FA, Helton KJ, Ellison DW, McKinnon PJ, Gajjar A, Pai Panandiker AS. Radiation therapy and adjuvant chemotherapy in a patient with a malignant glioneuronal tumor and underlying ataxia telangiectasia: a case report and review of the literature. J Clin Oncol. 31(1):e12-4, 2013.
Pai Panandiker AS, Beltran C, Billups CA, McGregor LM, Furman WL, Davidoff AM. Intensity modulated radiation therapy provides excellent local control in high-risk abdominal neuroblastoma. Pediatr Blood Cancer September 28, 2012.
Zhang B, Pai Panandiker A, Yan B. A nano-combinatorial approach to developing cancer diagnostics: nano-combinatorial diagnostics discovery. Nanomedicine (Lond) 7(7):937-40, 2012.
Qaddoumi I, Sane M, Li S, Kocak M, Pai-Panandiker A, Harreld J, Klimo P, Wright K, Broniscer A, Gajjar A. Diagnostic utility and correlation of tumor markers in the serum and cerebrospinal fluid of children with intracranial germ cell tumors. Childs Nerv Syst. 28(7):1017-24, 2012.
Pai Panandiker AS, Sharma S, Naik MH, Wu S, Hua CH, Beltran C, Krasin MJ, Merchant TE. Novel assessment of renal motion in children as measured via 4-dimensional computed tomography. Int J Radiat Oncol Biol Phys. 82(5):1771-6, 2012.
Pai Panandiker AS, Merchant, TE, Beltran C, Wu S, Sharma S, Boop FA, Jenkins JJ, Helton KJ, Wright KD, Broniscer A, Kun LE, Gajjar A. Sequencing of local therapy affects the pattern of treatment failure and survival in children with atypical teratoid rhabdoid tumors of the central nervous system. Int J Radiat Oncol Biol Phys. 82(5):1756-63, 2012.
Qaddoumi I, Carey SS, Conklin H, Jenkins J, Sabin N, Boop F, Pai-Panandiker A, Baker J, Wright K, Broniscer A, Gajjar A. Characterization, treatment and outcome of intracranial neoplasms in the first 120 days of life. J Child Neurol. 6(8):988-94, 2011.
Li X, Zhou H, Yang L, Du G, Pai-Panandiker AS, Huang X, Yan B. Enhancement of cell recognition in vitro by dual-ligand cancer targeting gold nanoparticles. Biomaterials 32(10):2540-5, 2011.
Broniscer A, Baker JN, Tagen M, Onar-Thomas A, Gilbertson RJ, Davidoff AM, Pai Panandiker AS, Leung W, Chin TK, Stewart CF, Kocak M, Rowland C, Merchant TE, Kaste SC, Gajjar A. Phase I study of vandetanib during and after radiotherapy in children with diffuse intrinsic pontine glioma. J Clin Oncol 28(31):4762-8, 2010.
Beltran C, Pai Panandiker AS, Krasin MJ, Merchant TE. Daily image-guided localization for neuroblastoma. J Appl Clin Med Phys 11(4):3388, 2010.
Robbins JR, Krasin MJ, Pai Panandiker AS, Watkins A, Wu J, Santana VM, Furman WL, Davidoff AM, McGregor LM. Radiation therapy as part of local control for metastatic neuroblastoma: the St. Jude Children’s Research Hospital experience. J Pediatr Surg 45(4):678-86, 2010.
Tendulkar RD, Pai Panandiker AS, Wu S, Kun LE, Broniscer A, Sanford RA, Merchant TE. Irradiation of pediatric high-grade spinal cord tumors. Int J Radiat Oncol Biol Phys 78(5):1451-6, 2010.
Pai Panandiker AS, McGregor L, Krasin MJ, Wu S, Xiong X, Merchant TE. Loco-regional tumor progression after radiation therapy influences overall survival in pediatric patients with neuroblastoma. Int J Radiat Oncol Biol Phys 76(4):1161-5, 2010.
Pai Panandiker A, Ning H, Likhacheva A, Ullman K, Arora B, Ondos J, Karimpour S, Packer R, Miller R, Citrin D. Craniospinal irradiation with spinal IMRT to improve target homogeneity. Int J Radiat Oncol Biol Phys 68(5):1402-9, 2007.
Shen DW, Su A, Liang XJ, Pai Panandiker A, Gottesman MM. Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells. Br J Cancer 91(2):270-6, 2004.
Chauhan SS, Liang XJ, Su AW, Pai Panandiker A, Shen DW, Hanover JA, Gottesman MM. Reduced endocytosis and altered lysosome function in cisplatin-resistant cell lines. Br J Cancer 88(8):1327-34, 2003.
Last update: January 2013
