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Finding Cures. Saving Children.
Clinical Protocol Scientific Review and Monitoring Committee
The Clinical Protocol Scientific Review and Monitoring Committee (CPSRMC) is responsible for scientific review of clinical protocols, including:
- Scientific rationale
- Study design
- Appropriateness of biostatistical endpoints
It monitors the progress of all institutional protocols to ensure:
- That they adhere to the initial study design
- That planned patient accrual is occurring
- That planned stopping criteria are followed
- That any observed toxicities are consistent with those expected
The CPSRMC has the authority to suspend or close protocols that fail to meet these requirements.
