AT1026 (P1026): (IMPAACT 1026S) Pharmacokinetic Properties of Antiretroviral Drugs During Pregnancy


Infectious Diseases : HIV Infection


Studies have shown that women and men differ in how their bodies metabolize certain drugs. Pregnancy may have an additional effect on drug metabolism for women. Pregnant women experience unique physiological changes that may result in clinically significant changes in drug pharmacokinetics (the way the body uses the drug) and pharmacodynamics (how the drug acts on the body).

This study will evaluate the pharmacokinetics and pharmacodynamics of currently prescribed antiretroviral drugs and interacting combinations of these drugs in pregnant HIV-infected women.



For the current eligibility status of this clinical study, referring physicians must contact St. Jude Children's Research Hospital at 1-866-2ST-JUDE (1-866-278-5833).


Katherine Knapp, MD
St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN  38105  USA
Voice:   1-866-2ST-JUDE  (1-866-278-5833)
FAX:     901-521-9005

Referring or consulting physicians only:
For all other inquiries about St. Jude Children's Research Hospital studies:

The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.