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Associated Hematology Studies : Sickle cell disease
This is a BABY HUG II study follow-up to learn about the long-term effects of the drug hydroxyurea (HU). The BABY HUG study found that treatment with HU in very young children with sickle cell anemia did not prevent organ damage in the primary endpoints of the spleen and kidneys, but did prevent painful crises, dactylitis, acute chest syndrome and hospitalizations.
The purpose of HUG3 is to study the long-term safety and efficacy of HU treatment in children. Follow-up of the BABY HUG cohort will provide important information about whether HU treatment should be given to infants and the best age to begin treatment.
Participant was enrolled in the HUG2 study for at least 24 months.
Participant received a stem cell transplant.
Winfred Wang, MD
The above information is intended to provide only a basic description about a research protocol that may be currently active at St. Jude. The details made available here may not be the most up-to-date information on protocols used by St. Jude. To receive full details about a protocol and its status and or use at St. Jude, a physician must contact St. Jude directly.