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Finding Cures. Saving Children.
Robert G. Webster, PhD
Member, St. Jude Faculty
Rose Marie Thomas Chair
Departments
Infectious Diseases
Education
PhD - Australian National University, Canberra
Research Interests
- The emergence and control of influenza viruses
- Viral immunology
Dr. Webster’s interests include the structure and function of influenza virus proteins and the development of new vaccines and antivirals; the importance of influenza viruses in wild birds as a major reservoir of influenza viruses and their role in the evolution of new pandemic strains for humans and lower animals. His curriculum vitae contains over 400 original articles and reviews on influenza viruses. He has mentored many individuals who have been successful in contributing to our knowledge of influenza as an emerging pathogen.
Selected Publications
Recent citations from more than 500 publications:
Salomon R, Webster RG. The influenza virus enigma. Cell. Feb 6;136(3):402-10, 2009.
Aldridge JR Jr, Moseley CE, Boltz DA, Negovetich NJ, Reynolds C, Franks J, Brown SA, Doherty PC, Webster RG, Thomas PG. TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc Natl Acad Sci U S A Mar 31;106(13):5306-11, 2009.
Yen HL, Guan Y, Peiris M, Webster RG. H5N1 in Asia, in “Monographs in Virology Volume 27-Avian Influenza”, edited by Klenk HD, Matrosovich MN, Stech J, Karger, 2008.
Govorkova EA, Ilyushina NA, Boltz D, Douglas A, Yilmaz N, Webster RG. Efficacy of oseltamivir therapy in ferrets inoculated with different clades of H5N1 influenza virus. Antimicrob Agents Chemother 51:1414-1424, 2007.
Boltz DA, Bouangngeun B, Sinthasak S, Phommachanh P, Rolston S, Chen HK, Guan Y, Peiris JSM, Smith GJD, Webster RG. H5N1 influenza viruses in Lao People’s Democratic Republic. Emerg Infect Dis 12:1593-1595, 2006.
Webster RG, Govorkova EA. H5N1 influenza-continuing evolution and spread. N Engl J Med 355:2174-2177, 2006.
Lipatov AS, Hoffmann E, Salomon R, Yen HL, Webster RG. Cross-protectiveness and immunogenicity of influenza A/Duck/Singapore/3/97 (H5) vaccines against infection with A/Vietnam/1203/04 (H5N1) virus in ferrets. J Infect Dis 194:1040-1043, 2006.
Govorkova EA, Webby RJ, Humberd J, Seiler JP, Webster RG. Immunization with reverse-genetics-produced H5N1 influenza vaccine protects ferrets against homologous and heterologous challenge. J Infect Dis 194:159-167, 2006.
Obenauer JC, Denson J, Mehta PK, Su X, Mukatira S, Finkelstein DB, Xu X, Wang J, Ma J, Fan Y, Rakestraw KM, Webster RG, Hoffmann E, Krauss S, Zheng J, Zhang Z, Naeve CW. Large-scale sequence analysis of avian influenza isolates. Science 17:1576-1580, 2006.
Webster RG, Peiris M, Chen H, Guan Y. H5N1 outbreaks and enzootic influenza. Emerg Infect Dis 12:3-8, 2006.
Salomon R, Franks J, Govorkova EA, Ilyushina NA, Yen HL, Hulse-Post DJ, Humberd J, Trichet M, Rehg JE, Webby RJ, Webster RG, Hoffmann E. The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04. J Exp Med 20:689-697, 2006.
Russel CJ, Webster RG. The genesis of a pandemic influenza virus. Cell 122:368-371, 2005.
Last update: May 2009
