Robert Webster, PhD

Robert G. Webster, PhD

Member, St. Jude Faculty
Rose Marie Thomas Chair

Departments

Infectious Diseases


Education

MSc - Otago University, New Zealand
PhD - Australian National University, Canberra
DSc - Otago University, New Zealand


Honors


Research Interests

Dr. Webster’s interests include the structure and function of influenza virus proteins and the development of new vaccines and antivirals; the importance of influenza viruses in wild birds as a major reservoir of influenza viruses and their role in the evolution of new pandemic strains for humans and lower animals. His curriculum vitae contains over 600 original articles and reviews on influenza viruses. He has mentored many individuals who have been successful in contributing to our knowledge of influenza as an emerging pathogen.


Selected Publications

Selected from more than 650 publications:

Webster RG. Mammalian-transmissible H5N1 influenza: the dilemma of dual-use research. MBio 3, 2012.

Pascua PN, Song MS, Lee JH, Baek YH, Kwon HI, Park SJ, Choi EH, Lim GJ, Lee OJ, Kim SW, Kim CJ, Sung MH, Kim MH, Yoon SW, Govorkova EA, Webby RJ, Webster RG, Choi YK. Virulence and transmissibility of H1N2 influenza virus in ferrets imply the continuing threat of triple-reassortant swine viruses. Proc Natl Acad Sci U S A 109:15900-5, 2012.

Krauss S, Webster RG. Predicting the next influenza virus. Science 337:644, 2012.

Negovetich NJ, Feeroz MM, Jones-Engel L, Walker D, Alam SM, Hasan K, Seiler P, Ferguson A, Friedman K, Barman S, Franks J, Turner J, Krauss S, Webby RJ, Webster RG. Live bird markets of Bangladesh: H9N2 viruses and the near absence of highly pathogenic H5N1 influenza. PLoS One 6:e19311, 2011.

Yen HL, Liang CH, Wu CY, Forrest HL, Ferguson A, Choy KT, Jones J, Wong DD, Cheung PP, Hsu CH, Li OT, Yuen KM, Chan RW, Poon LL, Chan MC, Nicholls JM, Krauss S, Wong CH, Guan Y, Webster RG, Webby RJ, Peiris M. Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets. Proc Natl Acad Sci U S A 108:14264-9, 2011.

Kayali G, El-Shesheny R, Kutkat MA, Kandeil AM, Mostafa A, Ducatez MF, McKenzie PP, Govorkova EA, Nasraa MH, Webster RG, Webby RJ, Ali MA. Continuing threat of influenza (H5N1) virus circulation in Egypt. Emerg Infect Dis 17:2306-8, 2011.

Vijaykrishna D, Smith GJ, Pybus OG, Zhu H, Bhatt S, Poon LL, Riley S, Bahl J, Ma SK, Cheung CL, Perera RA, Chen H, Shortridge KF, Webby RJ, Webster RG, Guan Y, Peiris JS. Long-term evolution and transmission dynamics of swine influenza A virus. Nature 473:519-22, 2011.

Kim JK, Kayali G, Walker D, Forrest HL, Ellebedy AH, Griffin YS, Rubrum A, Bahgat MM, Kutkat MA, Ali MA, Aldridge JR, Negovetich NJ, Krauss S, Webby RJ, Webster RG. Puzzling inefficiency of H5N1 influenza vaccines in Egyptian poultry. Proc Natl Acad Sci U S A 107:11044-9, 2010.

Barber MR, Aldridge JR Jr, Webster RG, Magor KE.Association of RIG-I with innate immunity of ducks to influenza. Proc Natl Acad Sci U S A 107:5913-8, 2010.

Aldridge JR Jr, Moseley CE, Boltz DA, Negovetich NJ, Reynolds C, Franks J, Brown SA, Doherty PC, Webster RG, Thomas PG. TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc Natl Acad Sci U S A Mar 31;106(13):5306-11, 2009.

Salomon R, Webster RG. The influenza virus enigma. Cell Feb 6;136(3):402-10, 2009.

Pereira HG, Tumova B, Webster RG. Antigenic relationship between influenza A viruses of human and avian origins. Nature 215:982 983, 1967.

Fazekas de St Groth S, Webster RG. Disquisitions on original antigenic sin. I. Evidence in man. J Exp Med 124:331 345, 1966.

Fazekas de St Groth S, Webster RG, Datyner A. (Discovery of Coomassie Blue Stain). Two new staining procedures for quantitative estimation of proteins on electrophoresis strips. Biochim Biophys Acta 71:377 391, 1963.

Last update: February 2013