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Finding Cures. Saving Children.
Solid Tumor Protocols / Clinical Studies
For information on these and other studies, referring physicians may e-mail protocolinfo@stjude.org or call toll free physician referral line, 1-888-226-4343. If you are not a physician, please e-mail info@stjude.org for information on St. Jude studies.
Phase I Study of Bevacizumab and Sorafenib Combined with Low Dose Cyclophosphamide in Patients with Refractory Solid Tumors and Leukemia
For: Recurrent or refractory solid tumors and leukemias
International Pediatric Adrenocortical Tumor Registry Data Collection
For: adrenocortical carcinoma
Phase II Study Incorporating Pegylated Interferon In The Treatment For Children With High-Risk Melanoma
For: Melanoma
A Phase I Trial of the Combination of Oxaliplatin and Etoposide in Recurrent or Refractory Pediatric Solid Tumors and Lymphomas
For: Recurrent or refractory solid tumors or lymphomas
A Dose Finding Study (Phase I) of the Combination of ZD1839 (Iressa®) and Irinotecan (CamptosarTM) Given Orally in Children with Refractory Solid Tumors (AstraZeneca Protocol IRUSIRES0181)
For: Refractory solid tumors including glioblastoma, rhabdomyosarcoma, neuroblastoma, and osteosarcoma
Protocol for the Study and Treatment of Patients with Intraocular Retinoblastoma
For: Retinoblastoma
Image Guided Radiotherapy for the Treatment of Musculoskeletal Tumors: A Phase II Prospective Evaluation of Radiation-related Treatment Effects
For: Ewing sarcoma; rhabdomyosarcoma; primitive neuroectodermal tumors (PNET) of the musculoskeletal system; soft tissue sarcomas; other bone sarcomas; chordoma
A Phase I Trial of the Humanized Anti-GD2 Antibody (HU14.18K322A) in Children and Adolescents with Neuroblastoma or Melanoma
For: Neuroblastoma or melanoma
Allogeneic Bone Marrow Transplantation for Children with Solid Malignancies
For: Solid tumors, Lymphoma
Non St. Jude Protocols
A Phase II Study of Trabectedin in Children with Recurrent Rhabdomyosarcoma, Ewing Sarcoma, or Non-Rhabdomyosarcoma Soft Tissue Sarcomas
For: Rhabdomyosarcoma, Ewing sarcoma, non-rhabdomyosarcoma soft tissue sarcomas
A Phase I Study of the Raf Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib (Bay 43-9006, NSC#724772, IND#69896) in Children with Refractory Solid Tumors or Refractory Leukemias (ADVL0413)
For: All Leukemias, Solid Tumors
A Phase I Study of Sunitinib (SU11248), an Oral Multi-Targeted Tyrosine Kinase Inhibitor, in Children with Refractory Solid Tumors (ADVL612)
For: Solid tumors
A Phase I Study of VEGF Trap (NSC# 724770, IND# 100137) in Children with Refractory Solid Tumors
For: All Solid Tumors, CNS Malignancies
Perinatal Neuroblastoma: Expectant Observation - A Children's Oncology Group Pilot Study
For: Neuroblastoma
A Phase III Study of Reduced Therapy in the Treatment of Children with Low and Intermediate Risk Extracranial Germ Cell Tumors (AGCT0132)
For: Germ cell tumor
Treatment of Recurrent or Resistant Pediatric Malignant Germ Cell Tumors with Paclitaxel, Ifosfamide and Carboplatin
For: Germ Cell Tumor
A Study to Determine the Activity of SCH 717454 in Subjects with Osteosarcoma or Ewing’s Sarcoma that has Relapsed after Standard Systemic Therapy (SCH Protocol: PO4720) (US IND BB-100343)
For: Solid tumors, osteosarcoma, Ewing sarcoma
A Phase I Pharmacokinetic Optimal Dosing Study of Intraventricular Topotecan for Children with Neoplastic Meningitis
For: Neoplastic meningitis
Treatment of Childhood Nasopharyngeal Carcinoma with Neoadjuvant Chemotherapy and Concomitant Chemoradiotherapy
For: Nasopharyngeal carcinoma
Treatment of Adrenocortical Tumors with Surgery plus Lymph Node Dissection and Multiagent Chemotherapy
For: Adrenocortical tumors
Treatment for Very Low, Low and Standard Risk Favorable Histology Wilms Tumor
For: Wilms Tumor
A Phase II Study of Sulindac and Tamoxifen in Patients with Desmoid Tumors that are Recurrent or Not Amenable to Standard Therapy (ARST0321)
For: Desmoid Tumor (also known as fibromatosis)
Vincristine, Dactinomycin, and Lower Doses of Cyclophosphamide with or without Radiation Therapy for Patients with Newly Diagnosed Low-Risk Embryonal/Botryoid/Spindle Cell Rhabdomyosarcoma
For: Rhabdomyosarcoma (embryonal/botryoid/spindle cell subtypes)
Risk-Based Treatment for Pediatric Non-Rhabdomyosarcoma Soft Tissue Sarcomas
For: Non-rhabdomyosarcoma soft tissue sarcomas
Randomized Study of Vincristine, Dactinomycin and Cyclophosphamide (VAC) versus VAC Alternating with Vincristine and Irinotecan (VI) for Patients with Intermediate-Risk Rhabdomyosarcoma (RMS)
For: Rhabdomyosarcoma
