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    Fabio Demontis, PhD

    Fabio Demontis, PhD

    Assistant Member, St. Jude Faculty


    Developmental Neurobiology


    Developmental Biology

    Contact Information

    Fabio Demontis, PhD
    Developmental Neurobiology
    MS 324, Room D2038C
    St. Jude Children's Research Hospital
    262 Danny Thomas Place
    Memphis, TN 38105-3678
    Phone: (901) 595-5444
    FAX: (901) 595-7641


    Laurea (MSc) - Medical School, University of Milano, Italy
    PhD - Max Planck Institute for Cell Biology and Genetics, Dresden, Germany
    Postdoctoral studies - Harvard Medical School/HHMI, Boston, Massachusetts

    Honors & Awards

    Research Interests

    Selected Publications

    Patel VK, Demontis F. GDF11/Myostatin and aging. Aging May;6(5):351-352, 2014.

    Demontis F, Patel VK, Swindell WR, Perrimon N. Intertissue control of the nucleolus via a myokine-dependent longevity pathway. Cell Reports June 12;7(5):1481-1494, 2014.

    Piccirillo R, Demontis F, Perrimon N, Goldberg AL. Mechanisms of muscle growth and atrophy in mammals and Drosophila. Developmental Dynamics June;7(5):1-14, 2014.

    Hunt LC, Demontis F. Whole-mount immunostaining of Drosophila skeletal muscle. Nature Protocols Dec;8(12):2496-501, 2013.

    Demontis F, Piccirillo R, Goldberg AL, Perrimon N. The influence of skeletal muscle on systemic aging and lifespan. Aging Cell Dec;12(6):943-9, 2013.

    Demontis F, Piccirillo R, Goldberg AL, Perrimon N. Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models. Disease Modelels & Mechanisms Nov;6(6):1339-52, 2013.

    Katewa SD, Demontis F, Kolipinski M, Hubbard A, Gill MS, Perrimon N, Melov S, Kapahi P. Intra-myocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Cell Metabolism Jul 3;16(1):97-103, 2012.

    Demontis F, Perrimon N. FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell Nov 24;143(5):813-25, 2010.

    Demontis F, Perrimon N. Integration of InR/FOXO signaling and dMyc activity during muscle growth regulates body size. Development Mar;136(6):983-93, 2009.

    Last updated: June 2014