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Finding Cures. Saving Children.
Diseases Treated by Stem Cell Transplant
Many malignant and non-malignant disorders can be treated with hematopoietic stem cell transplant. High-dose chemotherapy and subsequent autologous hematopoietic stem cell transplant is typically used for patients with high-risk solid tumors, lymphomas, and acute myeloid leukemia. Stem cell collection for these patients is ideally performed when bone marrow has minimal or no involvement by malignancy.
Diseases treated by autologous stem cell transplant include:
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acute myeloid leukemia (AML)
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brain tumors
- Ewing sarcoma
- germ cell tumors
- Hodgkin lymphoma
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neuroblastoma
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non-Hodgkin lymphoma (NHL)
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retinoblastoma
- rhabdomyosarcoma
- Wilms tumor
Allogeneic hematopoietic stem cell transplant has been successful as a treatment for various malignant and non-malignant disorders.
Malignant disorders treated by this method include:
- acute lymphoblastic leukemia (ALL)
- acute myeloid leukemia (AML)
- juvenile myelomonocytic leukemia (JMML)
- myelodysplastic syndrome (MDS)
- non-Hodgkin lymphoma (NHL)
- high-risk solid tumors, under certain circumstances.
Non-malignant disorders treated with this method include:
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bone marrow failure syndromes
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chronic granulomatous disease
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Fanconi anemia
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metabolic storage disorders
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osteogenesis imperfecta
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osteopetrosis
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severe aplastic anemia
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severe combined immunodeficiency syndrome (SCID)
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sickle cell anemia
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thalassemia
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Wiskott-Aldrich syndrome
