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Research
For information on these and other studies, referring physicians may e-mail protocolinfo@stjude.org or call our toll free physician referral line, 1-888-226-4343. If you are not a physician, please e-mail info@stjude.org for information on St. Jude studies.
T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus NK Cell Transplantation in Patients with Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant
For: Relapsed or refractory hematologic malignancies
A Pilot Feasibility Study of Gene Transfer for X-linked Severe Combined Immunodeficiency in Newly Diagnosed Infants Using a Self-Inactivating Lentiviral Vector to Transduce Autologous CD34+ Hematopoietic Cells
For: X-linked Severe Combined Immunodeficiency (SCID-X1)
Umbilical Cord Blood Transplantation In Patients With Hematologic Malignancies Using A Myeloablative Preparative Regimen
For: High risk hematologic malignancies
Non St. Jude Protocols
Randomised Study Of First Time Immune Tolerance Induction In Patients With Severe Type A Haemophilia With Inhibitor At High Risk Of Failure: Comparison Of Induction Of Immune Tolerance With FVIII Concentrates With Or Without Von Willebrand Factor
For: Type A haemophilia
Sparing Conversion to Abnormal TCD Elevation (SCATE) - a Phase III clinical trial to compare standard care (observation) with alternative therapy (hydroxyurea) for reducing the risk of converting to an abnormal TCD velocity in children with sickle cell anemia and conditional pre-treatment TCD velocities
For: Sickle cell anemia
TCD with Transfusions Changing to Hydroxyurea (TWiTCH): A Phase III randomized clinical trial to compare standard therapy (erythrocyte transfusions) with alternative therapy (hydroxyurea) for the maintenance of lowered TCD velocities in pediatric subjects with sickle cell anemia and abnormal pre-treatment TCD velocities
For: Sickle cell disease
